中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [8]
昆明植物研究所 [1]
中国科学院大学 [1]
采集方式
OAI收割 [9]
iSwitch采集 [1]
内容类型
期刊论文 [10]
发表日期
2022 [1]
2021 [1]
2016 [1]
2015 [1]
2013 [1]
2012 [1]
更多
学科主题
筛选
浏览/检索结果:
共10条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
题名升序
题名降序
作者升序
作者降序
发表日期升序
发表日期降序
Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555
作者:
Li, Ennian
;
Wang, Kai
;
Zhang, Bei
;
Guo, Siqi
;
Xiao, Senhao
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/08/16
DNMT1 inhibitor
A549 cell lines
HCT116 cell lines
antitumor activity
pharmacokinetic
Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway
期刊论文
OAI收割
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
作者:
Yang,Hao-Jie
;
Li,Ya-Nan
;
Yan,Chen
;
Yang,Jue
;
Zeng,Yan-Rong
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2022/04/02
Dysoxylum gotadhora
Rocaglaol derivatives
HCT116
Cytotoxic activity
MAPK pathway
FLAVAGLINES
Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1014, 页码: 17-23
作者:
Gao, Dan
;
Wang, Yini
;
Xie, Weiyi
;
Yang, Ti
;
Jiang, Yuyang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Metabolomics
UPLC/Q-TOF MS
Flexibilide
HCT-116 cells
Action mechanism
Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 4, 页码: 517-527
作者:
Ma, Yi-ming
;
Han, Wei
;
Li, Jia
;
Hu, Li-hong
;
Zhou, Yu-bo
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
physalin B
Physalis angulata L
HCT116 colon cancer cells
autophagy
reactive oxygen species
p38 mitogen-activated protein kinases
microtubule-associated proteins
apoptosis
ubiquitins
N-acetyl-L-cysteine
Synthesis and in vitro cytotoxic evaluation of novel -(3,4,5-trimethoxyphenyl)pyridin-2()-one derivatives
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2013, 卷号: 17, 期号: 3, 页码: 435-444
作者:
Chen, Taijie
;
Luo, Yu
;
Sheng, Li
;
Li, Jia
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Pyridin-2(1H)-one
Combretastatin A-4
Chan-Lam coupling reaction
Buchwald-Hartwig coupling reaction
HCT-116
Cytotoxicity
Cell cycle
Characterization of dihydroartemisinin-resistant colon carcinoma HCT116/R cell line
期刊论文
OAI收割
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2012, 卷号: 360, 期号: 1-2, 页码: 329-337
作者:
Lu, Jin-Jian
;
Chen, Si-Meng
;
Ding, Jian
;
Meng, Ling-Hua
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Dihydroartemisinin
Resistant
Proteomics
Anti-tumor
HCT116
Design, synthesis and biological evaluation of substituted 11H-benzo[a] carbazole-5-carboxamides as novel antitumor agents
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 12, 页码: 5878-5884
作者:
Wang, Yu-Qin
;
Li, Xiao-Hua
;
He, Qian
;
Chen, Yi
;
Xie, Yu-Yuan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
11H-benzo[a]carbazole
Anticancer
Synthesis
A549
HCT-116
In vivo
A new staurosporine analog from Actinomycetes Streptomyces sp (172614)
期刊论文
OAI收割
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2011, 卷号: 13, 期号: 8, 页码: 765-769
作者:
Li, Xiao-Bin
;
Tang, Jin-Shan
;
Gao, Hao
;
Ding, Rong
;
Li, Jia
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Streptomyces sp.
staurosporine analog
cytotoxicity
HCT 116
The p53 pathway is synergized by p38 mapk signaling to mediate 11,11 '-dideoxyverticillin-induced g(2)/m arrest
期刊论文
iSwitch采集
Febs letters, 2005, 卷号: 579, 期号: 17, 页码: 3683-3690
作者:
Chen, Y
;
Miao, ZH
;
Zhao, WM
;
Ding, J
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/05/10
11,11 '-dideoxyverticillin
G(2)/m arrest
P53
P38 mapk
Chk2
Anti-tumor
Hct-116 cell
The p53 pathway is synergized by p38 MAPK signaling to mediate 11,11 '-dideoxyverticillin-induced G(2)/M arrest
期刊论文
OAI收割
FEBS LETTERS, 2005, 卷号: 579, 期号: 17, 页码: 3683-3690
作者:
Chen, Y
;
Miao, ZH
;
Zhao, WM
;
Ding, J
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
11,11 '-dideoxyverticillin
G(2)/M arrest
p53
p38 MAPK
Chk2
anti-tumor
HCT-116 cell