机构

• 上海药物研究所 [11]
• 金属研究所 [6]
• 上海神经科学研究所 [2]
• 西北高原生物研究所 [2]
• 昆明植物研究所 [2]
• 中国科学院大学 [2]
• 更多

采集方式

• OAI收割 [29]
• iSwitch采集 [2]

内容类型

• 期刊论文 [31]

发表日期

• 2019 [1]
• 2017 [2]
• 2016 [3]
• 2014 [1]
• 2013 [1]
• 2012 [1]
• 更多

学科主题

• Oncology [3]
• Biochemist... [2]
• Chemistry [2]
• Pharmacolo... [2]
• Life Scien... [1]
• 药学 [1]
• 更多

筛选

浏览/检索结果: 共31条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 EGFR-specific CAR-T cells trigger cell lysis in EGFR-positive TNBC 期刊论文  OAI收割 Aging-Us, 2019, 卷号: 11, 期号: 23, 页码: 11054-11072 作者:  Y.Liu;  Y.H.Zhou;  K.H.Huang;  Y.Li;  X.J.Fang   |  收藏  |  浏览/下载：61/0  |  提交时间：2020/08/24 triple-negative breast cancer,human epidermal growth factor receptor,chimeric antigen receptor engineered T cells,negative breast-cancer,growth-factor receptor,therapy,amplification,inhibition,expression,challenges,mutations,her2,Cell Biology,Geriatrics & Gerontology   Anti-proliferation activity of terpenoids isolated from Euphorbia kansui in human cancer cells and their structure-activity relationship 期刊论文  OAI收割 CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 10, 页码: 766-774 作者:  Hou Jin-Jun;  Shen Yao;  Yang Zhou;  Fang Lin;  Cai Lu-Ying   |  收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 Terpenoids  Anti-proliferation activity  Human cancer cells  Structure-activity relationship   New ursane-type triterpenoids from Clerodendranthus spicatus 期刊论文  OAI收割 FITOTERAPIA, 2017, 卷号: 119, 页码: 69-74 作者:  Luo, Yong;  Cheng, Li-Zhi;  Luo, Qi;  Yan, Yong-Ming;  Wang, Shu-Mei 收藏  |  浏览/下载：22/0  |  提交时间：2017/07/31 Clerodendranthus spicatus  Ursane-type triterpenoids  Human cancer cells  Kidney fibroblast cells   Nuclear-targeting TAT-PEG-Asp(8)-doxorubicin polymeric nanoassembly to overcome drug-resistant colon cancer 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 8, 页码: 1110-1120 作者:  Pan, Zhen-zhen;  Wang, Hui-yuan;  Zhang, Meng;  Lin, Ting-ting;  Zhang, Wen-yuan   |  收藏  |  浏览/下载：48/0  |  提交时间：2019/01/08 doxorubicin  multidrug resistance  cell-penetrating peptide  poly(aspartic acid)  intranuclear delivery  nanoparticles  human colon cancer HCT8/ADR cells   Bufalin derivative BF211 inhibits proteasome activity in human lung cancer cells in vitro by inhibiting beta 1 subunit expression and disrupting proteasome assembly 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 7, 页码: 908-918 作者:  Sun, Peng;  Feng, Li-xing;  Zhang, Dong-mei;  Liu, Miao;  Liu, Wang   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 bufalin  ChanSu  cardiac steroids  proteasome beta 1 subunit  proteasome assembly  A549 human lung cancer cells  proteomics   Nuclear-targeting TAT-PEG-Asp_8-doxorubicin polymeric nanoassembly to overcome drug-resistant colon cancer 期刊论文  OAI收割 Acta Pharmacologica Sinica, 2016, 卷号: 37, 期号: 8, 页码: 1110 作者:  Pan Zhenzhen;  Wang Huiyuan;  Zhang Meng;  Lin Tingting;  Zhang Wenyuan   |  收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 MESOPOROUS SILICA NANOPARTICLES  CELL PENETRATING PEPTIDES  MULTIDRUG-RESISTANCE  P-GLYCOPROTEIN  PLGA NANOPARTICLES  COLORECTAL-CANCER  BREAST-CANCER  DELIVERY  CHEMOTHERAPY  INHIBITION  doxorubicin  multidrug resistance  cell-penetrating peptide  poly(aspartic acid)  intranuclear delivery  nanoparticles  human colon cancer HCT8/ADR cells   Cellulose-graft-poly(L-lactic acid) nanoparticles for efficient delivery of anti-cancer drugs 期刊论文  OAI收割 JOURNAL OF MATERIALS CHEMISTRY B, 2014, 卷号: 2, 期号: 39, 页码: 6749-6757 作者:  Dai, Lin;  Yang, Tingyuan;  He, Jing;  Deng, Lihong;  Liu, Jing 收藏  |  浏览/下载：29/0  |  提交时间：2014/12/01 BETULINIC ACID  MACROMOLECULAR THERAPEUTICS  CARBON NANOTUBES  HUMAN-MELANOMA  CELLULOSE  CANCER  CYTOTOXICITY  CELLS  CARBOXYMETHYLCELLULOSE  DEGRADATION   Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割 PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299 作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua 收藏  |  浏览/下载：47/0  |  提交时间：2015/05/14 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.   Glycoproteome Quantification of Human Lung Cancer Cells Exposed to Amorphous Silica Nanoparticles 期刊论文  OAI收割 acta chimica sinica, 2012, 卷号: 70, 期号: 19, 页码: 2059-2065 作者:  Hu Zhengyan;  Sun Zhen;  Zhang Yi;  Wu Ren'an;  Zou Hanfa 收藏  |  浏览/下载：31/0  |  提交时间：2015/11/13 silica NPs  hydrazide chemistry  quantitative glycoproteomics  cell membrane proteins  human lung cancer cells   Cytotoxic activities of some selected medicinal plants of the genus Euphorbia 期刊论文  OAI收割 JOURNAL OF MEDICINAL PLANTS RESEARCH, 2011, 卷号: 5, 期号: 31, 页码: 6766-6769 作者:  Wang, Xiao-yang;  Liu, Li-ping;  Zhu, Rui-xin;  Kang, Ting-guo;  Tong, Ling-jiang   |  收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 Cytotoxic activity  Euphorbia  human cancer cells