机构

• 上海药物研究所 [10]
• 昆明动物研究所 [3]
• 大连化学物理研究所 [2]
• 上海营养与健康研究所 [2]
• 合肥物质科学研究院 [2]
• 昆明植物研究所 [1]
• 更多

采集方式

• OAI收割 [21]
• iSwitch采集 [1]

内容类型

• 期刊论文 [20]
• 会议论文 [1]
• 学位论文 [1]

发表日期

• 2021 [3]
• 2020 [2]
• 2019 [6]
• 2018 [3]
• 2017 [3]
• 2015 [1]
• 更多

学科主题

• Biochemist... [1]
• Environmen... [1]
• Nutrition ... [1]
• Public, En... [1]
• Toxicology [1]

筛选

浏览/检索结果: 共22条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文  OAI收割 PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664 作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin   |  收藏  |  浏览/下载：55/0  |  提交时间：2021/12/01 IDH1-R132H inhibitors  synthesis  biological activity  docking  3-(indol-3-yl)-4-(pyrazolo-[3  4-c]pyridazin-3-yl)-maleimides   Isocitrate Dehydrogenase 2 Inhibitors for the Treatment of Hematologic Malignancies: Advances and Future Opportunities 期刊论文  OAI收割 MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21 作者:  Huang, Feng;  Tian, Tian;  Wu, Yizhe;  Che, Jinxin;  Yang, Haiyan   |  收藏  |  浏览/下载：30/0  |  提交时间：2021/06/15 Isocitrate dehydrogenase 2  IDH2  mutant  inhibitors  structure-activity relationship  blood cance   Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells 期刊论文  OAI收割 ONCOIMMUNOLOGY, 2021, 卷号: 10, 期号: 1, 页码: 13 作者:  Fan, Dandan;  Yue, Qi;  Chen, Jian;  Wang, Cong;  Yu, Ruilin   |  收藏  |  浏览/下载：46/0  |  提交时间：2021/08/17 Wnt/beta-catenin  IDH1-wildtype glioblastoma  Microglia  Phenotypic polarization   Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11 作者:  Wang, Yuwei;  Tang, Shuai;  Lai, Huanling;  Jin, Ruyi;  Long, Xu   |  收藏  |  浏览/下载：66/0  |  提交时间：2020/12/24 IDH1  gliomas  molecular docking  virtual screening  docking-based virtual screening   Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 5 作者:  Hu, Chujiao;  Zuo, Yu;  Liu, Jingqiu;  Xu, Heng;  Liao, Weike   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 Licochalcone A  Mutant IDH1  Selective inhibitor   Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants 期刊论文  OAI收割 CANCER SCIENCE, 2019, 页码: 9 作者:  Gao, Mingzhao;  Zhu, Hongmei;  Fu, Li;  Li, Yun;  Bao, Xubin   |  收藏  |  浏览/下载：42/0  |  提交时间：2020/07/01 AG-221  IDH2  leukemia  R140Q  R172K   Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236 作者:  Duan, Zhe;  Liu, Jingqiu;  Niu, Liping;  Wang, Jun;  Feng, Mingqian   |  收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01 IDH1 mutation  High-throughput screening  Pan-inhibitor  2-HG  Gliomas   Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation 期刊论文  OAI收割 JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 960-969 作者:  Xu, Guowang;  Zhou, Lina;  Wang, Zhichao;  Hu, Chunxiu;  Zhang, Chaoqi   |  收藏  |  浏览/下载：89/0  |  提交时间：2019/06/20 glioma  IDH1  metabolomics  lipidomics  metabolic reprogramming   Integrated metabolomics and lipidomics analyses reveal metabolic reprogramming in human glioma with idh1 mutation 期刊论文  iSwitch采集 Journal of proteome research, 2019, 卷号: 18, 期号: 3, 页码: 960-969 作者:  Zhou, Lina 收藏  |  浏览/下载：109/0  |  提交时间：2019/05/08 Glioma  Idh1  Metabolomics  Lipidomics  Metabolic reprogramming   Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 4, 页码: 589-603 作者:  Liu, Xiaoqi;  Hu, Yuanyuan;  Gao, Anhui;  Xu, Meng   |  收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 3-Aryl-4-indolyl-maleimides  IDH1/R132H inhibitors  Tumor 2-HG  Synthesis