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浏览/检索结果: 共847条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16 作者:  Zeng, Gongruixue;  Xu, Gaoya;  Gao, Lixin;  Zheng, Xiaoli;  Chi, Xinglong   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/04/01 Proteasome inhibitors  Macrocycle  Stability  Anti-cancer activities   Discovery of novel biaryl urea derivatives against IL-1/3 release with low toxicity based on NEK7 inhibitor 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 12 作者:  Wang, Leibo;  Zhu, Kehan;  Tian, Ziyang;  Wang, Haoyu;  Jia, Yulei   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/01/14 NLRP3 inflammasome  NEK7  NLRP3-NEK7  Inhibitors   Design, synthesis and activity evaluation of novel quinazolinone compounds as TRPC5 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 155, 页码: 20 作者:  Bai, Longhui;  Xiang, Yu;  Shen, Meiling;  Han, Yujun;  Li, Penghua   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/04/01 TRPC5  Inhibitors  Structural modifications and optimizing  Synthesis  Quinazolinone compounds  Activity evaluation   Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21 作者:  Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/12/25 Synthetic lethal  MSI tumors  WRN inhibitors  Triazolo-pyrimidine derivatives   Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22 作者:  Guma, Samuel Desta;  Zhou, Zhaoyin;  Song, Kang;  Yang, Feipu;  Suo, Jin   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/12/11 SARS-CoV-2  3CL pro inhibitors  Peptidomimetics  Spiropyrrolidine derivatives   Machine learning models and computational simulation techniques for prediction of anti-corrosion properties of novel benzimidazole derivatives 期刊论文  OAI收割 MATERIALS TODAY COMMUNICATIONS, 2024, 卷号: 41, 页码: 23 作者:  Ekeocha, Christopher Ikechukwu;  Uzochukwu, Ikechukwu Nelson;  Etim, Ini-Ibehe Nabuk;  Onyeachu, Benedict Ikenna;  Oguzie, Emeka Emmanuel   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/12/20 Corrosion inhibitors  DFT  MD simulation  predictive model  machine learning   Discovery of Alkyl Conjugated Diene Diacids as Novel ACLY Inhibitors 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 11, 页码: 3476-3489 作者:  Cheng, Tingting;  Song, Gaolei;  Cheng, Long;  Wang, Fan;  Sun, Xinyu   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/02/28 metabolic diseases  ATP-citrate lyase (ACLY)  lipogenesis  ACLY inhibitors  dienyldicarboxylic acid   Haperforatones A-M, thirteen undescribed limonoids from Harrisonia perforata with anti-inflammatory activity 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 151, 页码: 14 作者:  Wang, Qing;  Wu, Zhitao;  Li, Chenyue;  Qin, Guoqing;  Hu, Xianggang   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/09/26 Harrisonia perforata  UPLC-Q-TOF-MS  Mass Defect Filtering  Limonoids  NO inhibitors  Molecular docking  Anti-inflammatory   TRIP13-a potential drug target in cancer pharmacotherapy 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 151, 页码: 11 作者:  Bunu, Samuel Jacob;  Cai, Haiyan;  Wu, Leyun;  Zhang, Hui;  Zhou, Zhaoyin   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/09/26 AAA plus ATPase  TRIP13  Cancer  Drug target  Small-molecule inhibitors   Design, Synthesis, and Biological Evaluation of HDAC Inhibitors Containing Natural Product-Inspired N-Linked 2-Acetylpyrrole Cap 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 19, 页码: 26 作者:  Zhang, Han;  Shen, Qianqian;  Hu, Zhu;  Wu, Pei-Qian;  Chen, Yi   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/11/26 HDAC inhibitors  anti-cancer activity  natural products  pyrrole derivatives  molecular docking  molecular dynamics simulation