中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [7]
合肥物质科学研究院 [1]
采集方式
OAI收割 [8]
内容类型
期刊论文 [7]
会议论文 [1]
发表日期
2022 [1]
2021 [1]
2020 [1]
2019 [1]
2017 [1]
2011 [3]
更多
学科主题
筛选
浏览/检索结果:
共8条,第1-8条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Learning with uncertainty to accelerate the discovery of histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitors
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 14
作者:
Wang, Dong
;
Wu, Zhenxing
;
Shen, Chao
;
Bao, Lingjie
;
Luo, Hao
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2023/04/10
uncertainty estimation
graph neural network
KDM1A
LSD1 inhibitors
upper confidence bound method
virtual screening
Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2021, 页码: 8
作者:
Sun, Yin
;
Li, Na
;
Su, Mingbo
;
Wang, Xiaowen
;
Zhao, Dongmei
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Divalent tranylcypromine
LSD1 inhibitor
MV4-11 antiproliferative activity
CD86 mRNA expression
Linker
Selectivity
Biological roles of LSD1 beyond its demethylase activity
期刊论文
OAI收割
CELLULAR AND MOLECULAR LIFE SCIENCES, 2020
作者:
Gu, Feiying
;
Lin, Yuxin
;
Wang, Zhun
;
Wu, Xiaoxin
;
Ye, Zhenyue
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/11/26
LSD1
Demethylase
Ubiquitylation
FBXW7
Non-catalytic
Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 844-847
作者:
Wang, Xiaowen
;
Su, Mingbo
;
Li, You
;
Liu, Tongchao
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
LSD1 inhibitor
Tranylcypromine
Menin-MLL1 protei n-protein interaction inhibitor
MV4-11 antiproliferative activity
Structure activity relationship
Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 101-112
作者:
Ji, Yue-Yang
;
Lin, Sen-Dong
;
Wang, Yu-Jie
;
Su, Ming-Bo
;
Zhang, Wei
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Tranylcypromine
LSD1
Stereoselective cyclopropanation
Chiral synthesis
MAO-A
MAO-B
Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells
期刊论文
OAI收割
CELL RESEARCH, 2011, 卷号: 21, 期号: 10, 页码: 1424-1435
作者:
Wang, Quan
;
Xu, Xinxiu
;
Li, Jun
;
Liu, Jing
;
Gu, Haifeng
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
lithium
induced pluripotent stem cells
iPS
GSK3 beta
Nanog
LSD1
histone demethylase
赖氨酸特异性去甲基化酶1催化反应机制的理论研究
会议论文
OAI收割
作者:
孔祥谦
;
欧阳斯盛
;
梁中洁
;
叶飞
;
陈丽敏
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
分子动力学模拟
QM/MM
LSD1
lithiumanantipsychoticdruggreatlyenhancesthegenerationofinducedpluripotentstemcells
期刊论文
OAI收割
cellresearch, 2011, 卷号: 21, 期号: 10, 页码: 1424
作者:
Wang Quan
;
Xu Xinxiu
;
Li Jun
;
Liu Jing
;
Gu Haifeng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
MOUSE FIBROBLASTS
SOMATIC-CELLS
EXPRESSION
COMPLEX
NANOG
OCT4
INHIBITOR
PATHWAY
LINES
P53
lithium
induced pluripotent stem cells
iPS
GSK3 beta
Nanog
LSD1
histone demethylase