中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
近代物理研究所 [5]
地理科学与资源研究所 [4]
大连化学物理研究所 [4]
上海营养与健康研究所 [2]
沈阳应用生态研究所 [2]
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OAI收割 [32]
iSwitch采集 [1]
内容类型
期刊论文 [32]
中文期刊论文 [1]
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2024 [3]
2023 [1]
2020 [3]
2019 [2]
2018 [4]
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Biochemist... [1]
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浏览/检索结果:
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Discovery of PRMT3 Degrader for the Treatment of Acute Leukemia
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 8
作者:
Zou, Wanyi
;
Li, Mengna
;
Wan, Shili
;
Ma, Jingkun
;
Lian, Linan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/09/26
acute leukemia
MDM2
oxidative phosphorylation
PRMT3
PROTAC
An overview of PROTACs targeting MDM2 as a novel approach for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 8
作者:
Li, Huiwen
;
Cai, Xinhui
;
Yang, Xiaoyu
;
Zhang, Xuan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/09/26
MDM2
PROTAC
p53
MDMX
Targeted protein degradation
Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 270, 页码: 16
作者:
Lin, Zhitong
;
Liu, Chen
;
Yan, Ziqin
;
Cheng, Jing
;
Wang, Xiancheng
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/06/27
MDM2
p53
p21
Imidazolidinone
Apoptosis
High-Speed Optical Mode Switch in Lithium Niobate on Insulator
期刊论文
OAI收割
ACS PHOTONICS, 2023, 页码: 7
作者:
Jiang, Yongheng
;
Han, Xu
;
Li, Yiyang
;
Xiao, Huifu
;
Huang, Haijin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/07/12
Optical mode switch
Lithium niobate on insulator (LNOI)
Silicon nitride
Mode-division-multiplexing (MDM)
Heavy ion radiation-induced DNA damage mediates apoptosis via the Rp127a-Rp15-MDM2-p53/E2F1 signaling pathway in mouse spermatogonia
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 201, 页码: 12
作者:
Li, Hongyan
;
Zhang, Hong
;
Huang, Guomin
;
Dou, Zhihui
;
Xie, Yi
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/01/12
Ionizing radiation
Reproductive toxicology
Ribosomal stress
MDM2-p53 loop
Apoptosis
Targeting MDMX for Cancer Therapy: Rationale, Strategies, and Challenges
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Yu, De-Hua
;
Xu, Zhi-Yuan
;
Mo, Shaowei
;
Yuan, Li
;
Cheng, Xiang-Dong
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/10/26
MDMX
MDM2
p53
oncogene
tumor suppressor
inhibitors
The MDM2/MDMX/p53 axis in the adaptive stress response
期刊论文
OAI收割
TRANSLATIONAL CANCER RESEARCH, 2020, 卷号: 9, 期号: 3, 页码: 1993-1997
作者:
Wang, Bing
;
Rasmussen-Ivey, Cody
;
Little, John B.
;
Yuan, Zhi-Min
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/01/18
The MDM2/MDMX/p53 axis
mild stress
adaptive stress response
cell fate
MiR-1205 functions as a tumor suppressor by disconnecting the synergy between KRAS and MDM4/E2F1 in non-small cell lung cancer
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2019, 卷号: 9, 期号: 2, 页码: 312-+
作者:
Yan, Hong
;
Chen, Xiaoying
;
Li, Yu
;
Fan, Lei
;
Tai, Yusi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
KRAS
E2F1
MDM4
microRNA
oncogene activation
inactivator of tumor suppressor genes
Prolyl hydroxylase 3 stabilizes the p53 tumor suppressor by inhibiting the p53-MDM2 interaction in a hydroxylase-independent manner
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 25, 页码: 9949-9958
作者:
Xu, Yiming
;
Gao, Qiang
;
Xue, Yaqian
;
Li, Xiuxiu
;
Qin, Yanqing
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/09
p53
protein stability
mouse double minute 2 homolog (MDM2)
cancer stem cells
colon cancer
prolyl hydroxylase 3
How to Measure Urban Land Use Intensity? A Perspective of Multi-Objective Decision in Wuhan Urban Agglomeration, China
期刊论文
OAI收割
SUSTAINABILITY, 2018, 卷号: 10, 期号: 11, 页码: 15
作者:
Yang, Jun
;
Jin, Gui
;
Huang, Xianjin
;
Chen, Kun
;
Meng, Hao
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/05/23
urban land
factor substitution theory
optimal intensity
MDM
multi-objective decision
Wuhan urban agglomeration