中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [79]
大连化学物理研究所 [22]
海洋研究所 [14]
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期刊论文 [201]
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Advances in Sampling and Analytical Techniques for Single-Cell Metabolomics: Exploring Cellular Heterogeneity
期刊论文
OAI收割
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2025, 卷号: 39, 期号: 13, 页码: 14
作者:
Shen, Xinxin
;
Zhang, Fangyuan
;
Tang, Chunping
;
Sokovic, Marina
;
Misic, Danijela
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2025/06/23
cell isolation
mass spectrometry imaging
metabolite detection
sampling techniques
single-cell metabolomics
Diazonium-based derivatization for enhanced detection of phosphorylated metabolites by LC-MS in cells
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 255, 页码: 7
作者:
Wang, Yikang
;
Lin, Feifei
;
Zhu, Guozheng
;
Zhou, Xiaoxue
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2025/04/01
Phosphorylated metabolite
Derivatization
Chromatographic separation
Quantitative analysis
LC-MS
Hepatotoxic effects of environmentally relevant concentrations of polystyrene microplastics on senescent Zebrafish ( Danio rerio): Patterns of stress response and metabolomic alterations
期刊论文
OAI收割
AQUATIC TOXICOLOGY, 2025, 卷号: 279
作者:
Xie, Pengfei
;
Ommati, Mohammad Mehdi
;
Chen, Deshan
;
Chen, Weijun
;
Han, Lei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/11/27
Environmental exposure
Aged-animals
Hepatic stress
Metabolite profiling
Microplastic pollution
Endophytic bacteria and rhizosphere bacteria jointly inhibited the outbreak of banana wilt
期刊论文
OAI收割
RHIZOSPHERE, 2025, 卷号: 34
作者:
Wang, Xiaohu
;
Wei, Shengbo
;
Ye, Liujian
;
He, Shuang
;
Zhu, Qixia
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/11/27
Secondary metabolite
Soil microbial community
Synergistic effect
Evaluation of insect-tea quality and screening of tea-producing insects through non-targeted metabolomics and gut microbiota analysis
期刊论文
OAI收割
FOOD CHEMISTRY, 2025, 卷号: 493
作者:
Cao, Quan
;
Jiang, Feng
;
Zeng, Xiangfeng
;
Tai, Niufang
;
Cai, Wuzhao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/11/27
Insect tea
Tea-producing insects
Litsea coreana
Aglossa dimidiata
Martyria xeraula
Microbiota
Metabolite
Synergistic effect on corrosion behavior of X80 steel influenced by Pseudomonas aeruginosa and Acetobacter aceti
期刊论文
OAI收割
SEPARATION AND PURIFICATION TECHNOLOGY, 2024, 卷号: 351, 页码: 11
作者:
Liu, Dan
;
Li, Mankun
;
Han, Baochen
;
Liang, Yongmei
;
Hayat, Muhammad Dilawer
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/27
Microbiologically influenced corrosion
Pseudomonas aeruginosa
Acetobacter aceti
Synergetic corrosion
Metabolite
Mass balance, metabolism, and pharmacokinetics of [
14
C]amdizalisib, a clinical-stage novel oral selective PI3Kδ inhibitor for the treatment of non-hodgkin's lymphoma, in healthy Chinese volunteers
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Zhao, Chun-Yang
;
Zhang, Li-Jun
;
Sun, Chan
;
Yu, Cheng-Yin
;
Wang, Jian
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2025/01/06
amdizalisib
PI3K delta kinase
metabolism
mass balance
metabolite identification
pharmacokinetics
safety
Molecular basis of enhanced GLP-1 signaling mediated by GLP-1(9-36) in conjunction with LSN3318839
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 5069-5073
作者:
Li, Jie
;
Li, Guanyi
;
Mai, Yiting
;
Liu, Xiao
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2025/01/06
GLP-1(9-36)
Cryo-electron microscopy
Metabolite
Allosteric modulation
Gardenia jasminoides
Ellis. Polysaccharides Alleviated Cholestatic Liver Injury by Increasing the Production of Butyric Acid and FXR Activation
期刊论文
OAI收割
PHYTOTHERAPY RESEARCH, 2024, 页码: 13
作者:
Wang, Tianming
;
Tian, Tian
;
Zhu, Zhenyun
;
Fang, Su
;
Zhang, Lincong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2024/10/21
bile acid
butyric acid
cholestasis
FXR
Gardenia jasminoides Ellis. polysaccharide
intestinal bacterial metabolite
Simultaneous determination of BGT-002 and its acyl glucuronide metabolite ZM326E-M2 in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 243, 页码: 8
作者:
Zhu, Xueran
;
Cui, Shumin
;
Liu, Xinjing
;
Zhang, Mei
;
Xie, Zhifu
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/05/31
ATP-Citrate Lyase
BGT-002
Acyl glucuronide metabolite
Pseudo-MRM
LC-MS/MS
Pharmacokinetics