中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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合肥物质科学研究院 [20]
上海生物化学与细胞... [13]
上海神经科学研究所 [10]
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期刊论文 [101]
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Antithetical impacts of deleterious
LRP1B
mutations in non-squamous and squamous NSCLCs on predicting benefits from immune checkpoint inhibitor alone or with chemotherapy over chemotherapy alone: retrospective analyses of the POPLAR/OAK and CHOICE-01 trials
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2024
作者:
Wang, Jinliang
;
Zhou, Wenyong
;
Xu, Yu
;
Duan, Jianchun
;
Zhou, Qiaoxia
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/11/20
non-squamous NSCLC
squamous NSCLC
LRP1B deleterious mutations
predictive biomarker
immune checkpoint inhibitor
The human microbiota is a beneficial reservoir for SARS-CoV-2 mutations
期刊论文
OAI收割
MBIO, 2024, 页码: 15
作者:
Cao, Birong
;
Wang, Xiaoxi
;
Yin, Wanchao
;
Gao, Zhaobing
;
Xia, Bingqing
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/05/07
human microbiota
SARS-CoV-2 advantageous mutations
evolution
Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 96, 页码: 5
作者:
Lian, Xuanmin
;
Gao, Yue
;
Li, Xuemei
;
Wang, Peipei
;
Tong, Lexian
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/12/11
2-aminopyrimidine
FLT3 inhibitors
MV4-11
FLT3 mutations
Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:
Hua, Chen
;
Shena, Lijuan
;
Zoua, Fengming
;
Wua, Yun
;
Wanga, Beilei
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/11/10
Acquired resistance mutations
CDK9 inhibitors
Transcription
Single nucleotide polymorphisms
BAY1251152
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 886
作者:
Chen,Yuanzhi
;
He,Zhicheng
;
Yang,Shuting
;
Chen,Cheng
;
Xiong,Wenyong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/05/09
Runt-related transcription factor 1 (RUNX1)
High-grade serous ovarian carcinoma (HGSOC)
Apoptosis
EMT
Clinical therapeutic target
EPITHELIAL-MESENCHYMAL TRANSITIONS
HEPATOCELLULAR-CARCINOMA
TRANSCRIPTION FACTOR
TP53 MUTATIONS
UP-REGULATION
TUMOR-GROWTH
MIGRATION
PROLIFERATION
INVASION
FOXO1
Insights into the differentiation and adaptation within Circaeasteraceae from Circaeaster agrestis genome sequencing and resequencing
期刊论文
OAI收割
ISCIENCE, 2023, 卷号: 26, 期号: 3, 页码: 106159
作者:
Sun,Yanxia
;
Zhang,Aidi
;
Zhang,Xu
;
Landis,Jacob B.
;
Zhang,Huajie
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/07/30
DELETERIOUS MUTATIONS
POPULATION-SIZE
EVOLUTION
DIVERSITY
SELECTION
INTERFERENCE
PREDICTION
CONTRIBUTE
LINEAGES
FORMAT
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:
Yang,Qihong
;
Qin,Tong
;
An,Tao
;
Wu,Hongna
;
Xu,Gang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/07/30
PORCN inhibitor
WHN-88
Palmitoylation
Wnt-driven cancers
SIGNALING PATHWAY
PORCUPINE
STEM
GENE
ACYLTRANSFERASE
MUTATIONS
POLARITY
PROTEIN
RNF43
MICE
Simulating androgen receptor selection in designer yeast
期刊论文
OAI收割
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022, 卷号: 7
作者:
Zhang, Haoran
;
Zhang, Lu
;
Xu, Yipeng
;
Chen, Shaoyong
;
Ma, Zhenyi
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/12/23
Androgen receptor mutations
Androgen receptor antagonists
Prostate cancer
Saccharomyces cerevisiae
The Spatio-Temporal Pattern and Transition Mode of Recessive Cultivated Land Use Morphology in the Huaibei Region of the Jiangsu Province
期刊论文
OAI收割
LAND, 2022, 卷号: 11, 期号: 11, 页码: 16
作者:
Li, Xinyao
;
Wang, Lingzhi
;
Pijanowski, Bryan
;
Pan, Lingpeng
;
Omrani, Hichem
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2023/01/09
recessive cultivated land use transition
spatio-temporal pattern
point mutations detection
transition mode
Huaibei region of Jiangsu Province
The Spatio-Temporal Pattern and Transition Mode of Recessive Cultivated Land Use Morphology in the Huaibei Region of the Jiangsu Province
期刊论文
OAI收割
LAND, 2022, 卷号: 11, 期号: 11, 页码: 16
作者:
Li, Xinyao
;
Wang, Lingzhi
;
Pijanowski, Bryan
;
Pan, Lingpeng
;
Omrani, Hichem
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/01/09
recessive cultivated land use transition
spatio-temporal pattern
point mutations detection
transition mode
Huaibei region of Jiangsu Province