中国科学院机构知识库网格系统: 检索

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	The effect of malaria-induced alteration of metabolism on piperaquine disposition in Plasmodium yoelii infected mice and predicted in malaria patients 期刊论文 OAI收割 INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2024, 卷号: 64, 期号: 1, 页码: 11 作者: Xie, Yuewu; Zhang, Yifan; Lin, Feifei; Chen, Xiaoyue; Xing, Jie \| 收藏 \| 浏览/下载：11/0 \| 提交时间：2024/08/22 Malaria Drug metabolizing enzymes Piperaquine Clearance PBPK modelling
	Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity 期刊论文 OAI收割 XENOBIOTICA, 2021, 页码: 13 作者: Sun, Dongxue; Gao, Xiaoxia; Wang, Qiao; Krausz, Kristopher W.; Fang, Zhongze \| 收藏 \| 浏览/下载：61/0 \| 提交时间：2021/11/04 CYP podophyllotoxin metabolism liver microsomes recombinant drug-metabolizing enzymes hepatic and intestinal toxicity
	Current trends in drug metabolism and pharmacokinetics 期刊论文 OAI收割 ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1113-1144 作者: Li, Yuhua; Meng, Qiang; Yang, Mengbi; Liu, Dongyang; Hou, Xiangyu \| 收藏 \| 浏览/下载：52/0 \| 提交时间：2020/07/01 Pharmacokinetics Drug metabolism Drug-drug interactions Modeling Metabolizing enzymes Transporters Nuclear receptors Noncoding RNAs
	currenttrendsindrugmetabolismandpharmacokinetics 期刊论文 OAI收割 actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1113 作者: Liu Dongyang; Hou Xiangyu; Tang Lan; Wang Xin; Lyu Yuanfeng \| 收藏 \| 浏览/下载：39/0 \| 提交时间：2020/07/01 ARYL-HYDROCARBON RECEPTOR BLOOD-BRAIN-BARRIER ORGANIC ANION TRANSPORTERS CHRONIC KIDNEY-DISEASE PREGNANE-X-RECEPTOR P-GLYCOPROTEIN QUANTITATIVE PREDICTION CYTOCHROME-P450 ENZYMES DOWN-REGULATION IN-VIVO Pharmacokinetics Drug metabolism Drug-drug interactions Modeling Metabolizing enzymes Transporters Nuclear receptors Noncoding RNAs
	An Examination of the Potential Effect of Lipids on the First-Pass Metabolism of the Lipophilic Drug Anethol Trithione 期刊论文 OAI收割 JOURNAL OF PHARMACEUTICAL SCIENCES, 2011, 卷号: 100, 期号: 11, 页码: 5048-5058 作者: Yu, Hong-Zhen; Han, Si-Fei; Li, Ping; Zhu, Chun-Liu; Zhang, Xin-Xin \| 收藏 \| 浏览/下载：26/0 \| 提交时间：2019/01/08 anethol trithione medium chain triglycerides first-pass metabolism hepatic metabolism nonlinear pharmacokinetics dose proportionality drug metabolizing enzymes inhibition formulation lipids
	Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency 期刊论文 OAI收割 JOURNAL OF NEUROCHEMISTRY, 2009, 卷号: 111, 期号: 2, 页码: 537-546 Zhao, Yanling; Pan, Xiaoli; Zhao, Jing; Wang, Yang; Peng, Yun; Zhong, Chunjiu 收藏 \| 浏览/下载：31/0 \| 提交时间：2012/07/13 hippocampal neurogenesis pentose-phosphate pathway thiamine deficiency transketolase NONALCOHOLIC WERNICKE ENCEPHALOPATHY ALPHA-KETOGLUTARATE DEHYDROGENASE TUMOR-CELL PROLIFERATION ALZHEIMERS-DISEASE PYRUVATE-DEHYDROGENASE METABOLIZING ENZYMES DEPENDENT ENZYMES PROGENITOR CELLS BRAIN COMPLEX
	Function prediction for DNA-/RNA-binding proteins, GPCRs, and drug ADME-associated proteins by SVM 期刊论文 OAI收割 PROTEIN AND PEPTIDE LETTERS, 2008, 卷号: 15, 期号: 5, 页码: 463-468 作者: Cai, Congzhong; Xiao, Hanguang; Yuan, Qianfei; Liu, Xinghua; Wen, Yufeng \| 收藏 \| 浏览/下载：17/0 \| 提交时间：2019/04/09 Protein Function Prediction Dna-binding Proteins Rna-binding Proteins G-protein Coupled Receptors (Gpcrs) Drug Absorption Proteins Drug Metabolizing Enzymes Drug Distribution And Excretion Proteins Support Vector Machine (Svm)