机构

• 上海药物研究所 [5]
• 化学研究所 [1]
• 上海神经科学研究所 [1]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2024 [1]
• 2021 [1]
• 2019 [2]
• 2011 [1]
• 2009 [1]
• 2008 [1]
• 更多

学科主题

• Biochemist... [1]
• Neuroscien... [1]

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 The effect of malaria-induced alteration of metabolism on piperaquine disposition in Plasmodium yoelii infected mice and predicted in malaria patients 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2024, 卷号: 64, 期号: 1, 页码: 11 作者:  Xie, Yuewu;  Zhang, Yifan;  Lin, Feifei;  Chen, Xiaoyue;  Xing, Jie   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/08/22 Malaria  Drug metabolizing enzymes  Piperaquine  Clearance  PBPK modelling   Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity 期刊论文  OAI收割 XENOBIOTICA, 2021, 页码: 13 作者:  Sun, Dongxue;  Gao, Xiaoxia   |  收藏  |  浏览/下载：60/0  |  提交时间：2021/11/04 CYP  podophyllotoxin metabolism  liver microsomes  recombinant drug-metabolizing enzymes  hepatic and intestinal toxicity   Current trends in drug metabolism and pharmacokinetics 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1113-1144 作者:  Li, Yuhua;  Meng, Qiang;  Yang, Mengbi;  Liu, Dongyang;  Hou, Xiangyu   |  收藏  |  浏览/下载：52/0  |  提交时间：2020/07/01 Pharmacokinetics  Drug metabolism  Drug-drug interactions  Modeling  Metabolizing enzymes  Transporters  Nuclear receptors  Noncoding RNAs   currenttrendsindrugmetabolismandpharmacokinetics 期刊论文  OAI收割 actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1113 作者:  Liu Dongyang;  Hou Xiangyu;  Tang Lan;  Wang Xin;  Lyu Yuanfeng   |  收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01 ARYL-HYDROCARBON RECEPTOR  BLOOD-BRAIN-BARRIER  ORGANIC ANION TRANSPORTERS  CHRONIC KIDNEY-DISEASE  PREGNANE-X-RECEPTOR  P-GLYCOPROTEIN  QUANTITATIVE PREDICTION  CYTOCHROME-P450 ENZYMES  DOWN-REGULATION  IN-VIVO  Pharmacokinetics  Drug metabolism  Drug-drug interactions  Modeling  Metabolizing enzymes  Transporters  Nuclear receptors  Noncoding RNAs   An Examination of the Potential Effect of Lipids on the First-Pass Metabolism of the Lipophilic Drug Anethol Trithione 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL SCIENCES, 2011, 卷号: 100, 期号: 11, 页码: 5048-5058 作者:  Yu, Hong-Zhen;  Han, Si-Fei;  Li, Ping;  Zhu, Chun-Liu;  Zhang, Xin-Xin   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 anethol trithione  medium chain triglycerides  first-pass metabolism  hepatic metabolism  nonlinear pharmacokinetics  dose proportionality  drug metabolizing enzymes  inhibition  formulation  lipids   Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency 期刊论文  OAI收割 JOURNAL OF NEUROCHEMISTRY, 2009, 卷号: 111, 期号: 2, 页码: 537-546 Zhao, Yanling; Pan, Xiaoli; Zhao, Jing; Wang, Yang; Peng, Yun; Zhong, Chunjiu 收藏  |  浏览/下载：30/0  |  提交时间：2012/07/13 hippocampal neurogenesis  pentose-phosphate pathway  thiamine deficiency  transketolase  NONALCOHOLIC WERNICKE ENCEPHALOPATHY  ALPHA-KETOGLUTARATE DEHYDROGENASE  TUMOR-CELL PROLIFERATION  ALZHEIMERS-DISEASE  PYRUVATE-DEHYDROGENASE  METABOLIZING ENZYMES  DEPENDENT ENZYMES  PROGENITOR CELLS  BRAIN  COMPLEX   Function prediction for DNA-/RNA-binding proteins, GPCRs, and drug ADME-associated proteins by SVM 期刊论文  OAI收割 PROTEIN AND PEPTIDE LETTERS, 2008, 卷号: 15, 期号: 5, 页码: 463-468 作者:  Cai, Congzhong;  Xiao, Hanguang;  Yuan, Qianfei;  Liu, Xinghua;  Wen, Yufeng   |  收藏  |  浏览/下载：16/0  |  提交时间：2019/04/09 Protein Function Prediction  Dna-binding Proteins  Rna-binding Proteins  G-protein Coupled Receptors (Gpcrs)  Drug Absorption Proteins  Drug Metabolizing Enzymes  Drug Distribution And Excretion Proteins  Support Vector Machine (Svm)