机构

• 上海药物研究所 [6]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2022 [1]
• 2021 [1]
• 2020 [2]
• 2017 [2]
• 2014 [1]

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Vanguard is a Glucose Deprivation-Responsive Long Non-Coding RNA Essential for Chromatin Remodeling-Reliant DNA Repair 期刊论文  OAI收割 ADVANCED SCIENCE, 2022 作者:  Zhang, Ben;  Thorne, Rick Francis;  Zhang, Pengfei;  Wu, Mian;  Liu, Lianxin   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/12/23 genomic stability  HMGB1  long non-coding RNAs  PARP inhibitors  Vanguard   Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 31, 页码: 4 作者:  Xiang, Hao-Yue;  Chen, Jian-Yang;  Huan, Xia-Juan;  Chen, Yi;  Gao, Zhao-bing   |  收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24 Antiproliferative  Cancer  PARP inhibitors  Pyrrolo[12-b]pyridazine   Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+ 作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong   |  收藏  |  浏览/下载：36/0  |  提交时间：2020/12/24 PARP inhibitors resistance  BRCA2  COX-2  BIRC3  apoptotic resistance   Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+ 作者:  Chen, Hua-Dong   |  收藏  |  浏览/下载：105/0  |  提交时间：2020/12/24 PARP inhibitors resistance  BRCA2  COX-2  BIRC3  apoptotic resistance   Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang   |  收藏  |  浏览/下载：44/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   discoveryofpotent24difluorolinkerpolyadpribosepolymerase1inhibitorswithenhancedwatersolubilityandinvivoanticancerefficacy 期刊论文  OAI收割 actapharmacologicasinica, 2017, 卷号: 38, 期号: 11, 页码: 1521 作者:  Chen Wenhua;  Song Shanshan;  Ql Minghui;  Huan Xiajuan;  Wang Yingqing   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 PARP INHIBITORS  MEDICINAL CHEMISTRY  DRUG DISCOVERY  CANCER  THERAPY  DESIGN  FLUORINE  SUCCESS  PREDICT  METRICS  PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors   Synthesis of isoquinolinone-based tricycles as novel poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 12, 页码: 2669-2673 作者:  Chen, Jianyang;  Peng, Haixia;  He, Jinxue;  Huan, Xiajuan;  Miao, Zehong   |  收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 Isoquinolinone-based tricycles  PARP-1 inhibitors  Antitumor