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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [21]
上海神经科学研究所 [13]
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OAI收割 [41]
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期刊论文 [41]
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2022 [2]
2018 [1]
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(-)-Naringenin 4 ',7-dimethyl Ether Isolated from Nardostachys jatamansi Relieves Pain through Inhibition of Multiple Channels
期刊论文
OAI收割
MOLECULES, 2022, 卷号: 27, 期号: 5, 页码: 17
作者:
Gu, Ru-Rong
;
Meng, Xian-Hua
;
Zhang, Yin
;
Xu, Hai-Yan
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/06/15
(-)-Naringenin 4 ',7-dimethyl ether
analgesic candidate
mechanism study
delayed rectifier potassium currents
ion channels
(-)-Naringenin 4’,7-Dimethyl Ether Isolated from Nardostachys jatamansi Relieves Pain Through Inhibition of Multiple Channels
期刊论文
OAI收割
Molecules, 2022, 卷号: 5, 期号: 27, 页码: 1735
作者:
Ru-Rong Gu
;
Xian-Hua Meng
;
Yin Zhang
;
Hai-Yan Xu
;
Li Zhan
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/11/30
(-)-Naringenin 40,7-dimethyl ether
analgesic candidate
mechanism study
delayed rectifier potassium currents
ion channels
The permeation mechanism of organic cations through a CNG mimic channel
期刊论文
OAI收割
PLOS COMPUTATIONAL BIOLOGY, 2018, 卷号: 14, 期号: 8
作者:
Marchesi, Arin
;
Rodriguez, Alex
;
De March, Matteo
;
Onesti, Silvia
;
Laio, Alessandro
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2018/12/04
Nucleotide-gated Channels
Potassium Channels
Ion Selectivity
Calcium Channels
K++ Channel
Pore
Conduction
Binding
Rods
Permeability
Endothelium-independent vasorelaxant effect of 20(S)-protopanaxadiol on isolated rat thoracic aorta
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 页码: 1555-1562
作者:
Gan, Lu
;
Wang, Zhen-hua
;
Zhang, Hong
;
Zhou, Xin
;
Zhou, Hui
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2018/05/31
Ginsen
20(S)-protopanaxadiol
vasorelaxation
aortic rings
potassium channels
calcium channels
Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clampbased high-throughput screening techniques
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2016, 卷号: 37, 期号: 1, 页码: 105
作者:
Yue Jinfeng
;
Qiao Guanhua
;
Liu Ni
;
Chen Xueqin
;
Nan Fajun
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
POTASSIUM CHANNEL
KV7 CHANNELS
EPILEPSY
IDENTIFICATION
GENE
KCNQ2
channel activator
high-throughput screening
thallium flux assay
automated patch-clamp
ZG1732
ZG2083
KChIP-Like Auxiliary Subunits of Kv4 Channels Regulate Excitability of Muscle Cells and Control Male Turning Behavior during Mating in Caenorhabditis elegans
期刊论文
OAI收割
JOURNAL OF NEUROSCIENCE, 2015, 卷号: 35, 期号: 5, 页码: 1880-1891
作者:
Chen, Xin
;
Ruan, Mei-Yu
;
Cai, Shi-Qing
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2015/04/22
POTASSIUM CHANNELS
K+ CHANNEL
CARDIAC-ARRHYTHMIA
PRIMARY CULTURE
INACTIVATION
NEURONS
FAMILY
MODULATION
DEPENDENCE
COMPLEXES
Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BKCa channels and reducing intracellular Ca2+ levels
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 5, 页码: 587-596
作者:
Gai Xiangyun
;
Wei Yuhai
;
Zhang Wei
;
Wuren Tana
;
Wang Yaping
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/02/02
ACTIVATED POTASSIUM CHANNELS
K+ CHANNELS
CALCIUM-CHANNEL
Tibetan herb
echinacoside
pulmonary hypertension
high altitude
vasorelaxation
NO
BKCa
K-IR
artery ring
pulmonary arterial smooth muscle cells
Novel Bayesian classification models for predicting compounds blocking hERG potassium channels
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 8, 页码: 1093-1102
作者:
Liu, Li-li
;
Lu, Jing
;
Lu, Yin
;
Zheng, Ming-yue
;
Luo, Xiao-min
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
hERG
potassium channels
long QT syndrome
pharmacophore
modeling
Laplacian-modified Bayesian
extended-connectivity fingerprints
QSAR
Conopeptide Vt3.1 Preferentially Inhibits BK Potassium Channels Containing beta 4 Subunits via Electrostatic Interactions*
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 卷号: 289, 期号: 8, 页码: 4735-4742
作者:
Li, M
;
Chang, S
;
Yang, LJ
;
Shi, JY
;
McFarland, K
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2015/07/22
Electrophysiology
Molecular Modeling
Peptide Interactions
Potassium Channels
Toxins
4 Subunit
BK Channel
Activation
Conopeptide
Electrostatic Interaction
Targeting the Small- and Intermediate-Conductance Ca2+-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin Interface
期刊论文
OAI收割
NEUROSIGNALS, 2014, 卷号: 22, 期号: 2, 页码: 65-78
作者:
Cui, Meng
;
Qin, Guangrong
;
Yu, Kunqian
;
Bowers, M. Scott
;
Zhang, Miao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Small- and intermediate-conductance Ca2+-activated potassium channels
Small-molecule positive modulators
Structure-based drug discovery
Ataxia
Alcohol use disorders
Parkinson's disease