机构

• 上海药物研究所 [14]
• 生物物理研究所 [1]
• 水生生物研究所 [1]

采集方式

• OAI收割 [16]

内容类型

• 期刊论文 [15]
• 会议论文 [1]

发表日期

• 2026 [1]
• 2024 [2]
• 2023 [2]
• 2022 [1]
• 2019 [4]
• 2018 [4]
• 更多

学科主题

• Cell Biolo... [1]

筛选

浏览/检索结果: 共16条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of novel selective PRMT5-MTA inhibitors through structure-based virtual screening 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2026, 卷号: 168, 页码: 17 作者:  Ma, Ning;  Chen, Yang;  Liang, Yiru;  Chen, Xiaoxu;  Song, Fengnan   |  收藏  |   Excessive fatty acids activate PRMT5/MDM2/Drosha pathway to regulate miRNA biogenesis and lipid metabolism 期刊论文  OAI收割 LIVER INTERNATIONAL, 2024, 页码: 17 作者:  Hou, Aijun;  Xu, Xiaoding;  Zhang, Yu;  He, Hongxiu;  Feng, Yihan   |  收藏  |   Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19 作者:  Chen, Yuting;  Wang, Zekun;  Zhang, Junjie;  Shi, Qiongyu;  Yang, Hong   |  收藏  |   A patent review of PRMT5 inhibitors to treat cancer (2018-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2023, 页码: 28 作者:  Gao, Jing;  Yang, Jie;  Xue, Shengyu;  Ding, Hong;  Lin, Hua   |  收藏  |   Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20 作者:  Chen, Yuting;  Shi, Qiongyu;  Yang, Hong;  Li, Jiayi;  Zhou, Kaixin   |  收藏  |   Identification of PRMT5 inhibitors with novel scaffold structures through virtual screening and biological evaluations 期刊论文  OAI收割 JOURNAL OF MOLECULAR MODELING, 2022, 卷号: 28, 期号: 7, 页码: 184 作者:  Zhang, Qian;  Zhang, Lun;  Jin, Jia;  Fan, Yaohua;  Wang, Xiaoguang   |  收藏  |   Zebrafish prmt5 arginine methyltransferase is essential for germ cell development 期刊论文  OAI收割 DEVELOPMENT, 2019, 卷号: 146, 期号: 20, 页码: 16 作者:  Zhu, Junji;  Zhang, Dawei;  Liu, Xing;  Yu, Guangqing;  Cai, Xiaolian   |  收藏  |   Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity 期刊论文  OAI收割 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785 作者:  Zhu, Kongkai;  Shao, Jingwei;  Tao, Hongrui;  Yan, Xue;  Luo, Cheng   |  收藏  |   Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 317-333 作者:  Shao, Jingwei;  Zhu, Kongkai;  Du, Daohai;  Zhang, Yuanyuan;  Tao, Hongrui   |  收藏  |   Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4 alpha 期刊论文  OAI收割 THERANOSTICS, 2019, 卷号: 9, 期号: 9, 页码: 2606-2617 作者:  Zheng, Bai-Nan;  Ding, Chen-Hong;  Chen, Shi-Jie;  Zhu, Kongkai;  Shao, Jingwei   |  收藏  |