机构

• 上海药物研究所 [156]
• 上海生物化学与细胞... [45]
• 上海神经科学研究所 [29]
• 中国科学院大学 [29]
• 海洋研究所 [29]
• 昆明植物研究所 [22]
• 更多

采集方式

• OAI收割 [483]
• iSwitch采集 [41]

内容类型

• 期刊论文 [512]
• 学位论文 [7]
• CNKI期刊论文 [3]
• 会议论文 [2]

发表日期

• 2023 [12]
• 2022 [21]
• 2021 [17]
• 2020 [18]
• 2019 [25]
• 2018 [44]
• 更多

学科主题

• Biochemis... [46]
• Cell Biol... [19]
• Pharmacol... [17]
• Plant Sci... [17]
• Chemistry [14]
• Neuroscie... [14]
• 更多

筛选

浏览/检索结果: 共524条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13 作者:  Tang, Mingze;  Zhou, Xuan;  Shen, Qianqian;  Fang, Chen;  Peng, Xia   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/08/22 Receptor -interacting protein kinase 1  Histone deacetylases  Inhibitor  Molecular dynamics (MD) simulation  ADMET analysis   Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 16 作者:  An, Yuxiang;  Peng, Xia;  Wang, Tianchen;  Liu, Kaiyuan;  Feng, Dazhi   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/12/25 inhibitor  pharmacokinetic study  pyridazin-4-one  receptor-interacting protein kinase 1  selectivity   Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 21 作者:  Lan, Yaohan;  Ji, Yinchun;  Peng, Xia;  Duan, Wenhu;  Geng, Meiyu   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/08/22 autoimmune disease  necroptosis inhibitor  pharmacokinetic profile  receptor interacting protein kinase 1 (RIPK1)  structural optimization   New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9 作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/01/26 Chromone  Thiazolidine-2  4-dione  Protein tyrosine phosphatase 1B  Inhibitors   Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12 作者:  Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 Protein tyrosine phosphatases inhibitors  PTP1B inhibitors  Mechanism study  Molecular dynamics   Original Research Response to programmed cell death protein 1 antibody in patients with Epstein-Barr virus-associated intrahepatic cholangiocarcinoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF CANCER, 2023, 卷号: 194, 页码: 9 作者:  He, Wen-Zhuo;  Huang, Yu-Hua;  Hu, Wan-Ming;  Wang, Fang;  Xu, Yu-Xia   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/12/11 Epstein-Barr virus  Intrahepatic cholangiocarcinoma  Programmed cell death protein 1  Immunotherapy   Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane 期刊论文  OAI收割 PHYTOMEDICINE, 2023, 卷号: 119, 页码: 14 作者:  Chen, Xi;  Yang, Jia-bin;  Cao, Hui-hui;  Fang, Xiao-chuan;  Liu, Shan-hong   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 Liang-Ge-San  Dengue virus serotype 2  Heat shock protein 70  Caveolin1  Envelope protein   Discovery of HyT-Based Degraders of CDK9-Cyclin T1 Complex 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2023, 页码: 10 作者:  Lin, Rongkun;  Yang, Jie;  Liu, Ting;  Wang, Mingyu;  Ke, Chongrong   |  收藏  |  浏览/下载：40/0  |  提交时间：2023/10/17 CDK9  cyclin T1  degrader  hydrophobic tag  protein degradation   Spatial-Drug-Laden Protease-Activatable M1 Macrophage System Targets Lung Metastasis and Potentiates Antitumor Immunity 期刊论文  OAI收割 ACS NANO, 2023, 卷号: 17, 期号: 6, 页码: 5354-5372 作者:  Xu, Xiaoxuan;  Wang, Qiang;  Qian, Xindi;  Wu, Yao;  Wang, Jiaoying   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/03/27 M1 macrophages  lung metastasis  antitumor immunity  fibroblast activation protein protease  liposome   Root-Extracted lignanamides from Limonium gmelinii (Willd.) Kuntze with a potential PTP1B inhibitory activity by regulating PI3K/AKT signaling pathway 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 9 作者:  Tuohongerbieke, Amanguli;  Liu, Liu;  Li, Jun;  Xin, Xuelei;  Aisa, Haji Akber   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 Limonium gmelinii (Willd  ) Kuntze  Plumbaginaceae  Lignanamides  Protein tyrosine phosphatase 1B inhibitors  PI3K  AKT Signaling Pathway