机构

• 上海药物研究所 [117]
• 上海神经科学研究所 [62]
• 上海生物化学与细胞... [23]
• 昆明植物研究所 [22]
• 水生生物研究所 [18]
• 金属研究所 [15]
• 更多

采集方式

• OAI收割 [347]
• iSwitch采集 [10]

内容类型

• 期刊论文 [355]
• 会议论文 [2]

发表日期

• 2022 [9]
• 2021 [10]
• 2020 [13]
• 2018 [23]
• 2017 [14]
• 2016 [9]
• 更多

学科主题

• Neuroscie... [36]
• Biochemis... [34]
• Cell Biol... [22]
• Pharmacol... [18]
• Chemistry [13]
• Oncology [11]
• 更多

筛选

浏览/检索结果: 共357条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Bicyclic polyprenylated acylphloroglucinol-related meroterpenoids as potent DRAK2 inhibitors from Hypericum patulum 期刊论文  OAI收割 PHYTOCHEMISTRY, 2025, 卷号: 232, 页码: 10 作者:  Huang, Jin-Chang;  Jia, Xin-Yu;  Lv, Yi-Fan;  Xu, Hong-Hong;  Han, Ming   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/04/01 Hypericum patulum  Hypericaceae  Meroterpenoids  Hyperpatins A-H  Death-associated protein kinase-related  apoptosis-inducing kinase 2  Glucose-stimulated insulin secretion   Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13 作者:  Tang, Mingze;  Zhou, Xuan;  Shen, Qianqian;  Fang, Chen;  Peng, Xia   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/08/22 Receptor -interacting protein kinase 1  Histone deacetylases  Inhibitor  Molecular dynamics (MD) simulation  ADMET analysis   Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 16 作者:  An, Yuxiang;  Peng, Xia;  Wang, Tianchen;  Liu, Kaiyuan;  Feng, Dazhi   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/12/25 inhibitor  pharmacokinetic study  pyridazin-4-one  receptor-interacting protein kinase 1  selectivity   Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 21 作者:  Lan, Yaohan;  Ji, Yinchun;  Peng, Xia;  Duan, Wenhu;  Geng, Meiyu   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/08/22 autoimmune disease  necroptosis inhibitor  pharmacokinetic profile  receptor interacting protein kinase 1 (RIPK1)  structural optimization   Amlodipine inhibits Synaptotagmin-4's oncogenic activity on gastric cancer proliferation by targeting calcium signaling 期刊论文  OAI收割 FUNCTIONAL & INTEGRATIVE GENOMICS, 2024, 卷号: 24, 期号: 3, 页码: 14 作者:  Huang, Wen;  Yang, Shuo;  Deng, Minying;  Luo, Rongkui;  Liang, Huaiyu   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/05/22 Gastric cancer  synaptotagmin-4  Calcium ion channel  Mitogen-activated protein kinase signaling pathway  Amlodipine   Enantiomeric pairs of macrocyclic acylphloroglucinols from Syzygium szemaoense 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 6 作者:  Huang, Jin-Chang;  Hong Xu, Hong-;  Shi, Qing;  Lei, Chun;  Li, Jing-Ya   |  收藏  |  浏览/下载：32/0  |  提交时间：2023/04/10 Syzygium szemaoense  Acylphloroglucinol enantiomers  Death -associated protein kinase-related  apoptosis inducing protein kinase 2  ATP citrate lyase   Both AMP-activated and cAMP-dependent protein kinase regulate the expression of heat shock protein 70-2 gene in Neopyropia yezoensis 期刊论文  OAI收割 FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 13 作者:  Sun, Zhenjie;  Gu, Wenhui;  Feng, Zezhong;  Fan, Yaqin;  Niu, Jianfeng   |  收藏  |  浏览/下载：35/0  |  提交时间：2023/01/04 heat shock protein 70  high-temperature stress  AMP-activated protein kinase  cAMP-dependent protein kinase  Neopyropia yezoensis   Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15 作者:  Zhu, Cheng-Liang;  Luo, Xiaomin;  Tian, Tian;  Rao, Zijian;  Wang, Hanlin   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/08/16 AKT  Protein kinase B  PROTAC  Chemical degrader  Rational design   Rutaecarpine Promotes Adipose Thermogenesis and Protects against HFD-Induced Obesity via AMPK/PGC-1 alpha Pathway 期刊论文  OAI收割 PHARMACEUTICALS, 2022, 卷号: 15, 期号: 4, 页码: 18 作者:  Chen, Dandan;  Duan, Yanan;  Yu, Shuxiang;  Zhang, Xinwen;  Li, Ni   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/06/15 obesity  rutaecarpine  adipocytes  thermogenesis  peroxisome-proliferator-activated receptor gamma co-activator-1 alpha  AMP-activated protein kinase  browning   Necrosulfonamide Selectively Induces DNA Double-Strand Breaks in Acute Myeloid Leukemia Cells 期刊论文  OAI收割 CHEMICAL RESEARCH IN TOXICOLOGY, 2022, 卷号: 35, 期号: 3, 页码: 387-391 作者:  Chen, Shaokun;  Lai, Weiyi;  Li, Xiangjun;  Wang, Hailin   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/11/08 MIXED LINEAGE KINASE  INHIBITION  APOPTOSIS  PROTEIN  REPAIR  NECROPTOSIS  CANCER  DAMAGE  DEATH