机构

• 上海药物研究所 [9]
• 长春应用化学研究所 [5]
• 中国科学院大学 [3]
• 力学研究所 [2]
• 高能物理研究所 [2]
• 生物物理研究所 [1]
• 更多

采集方式

• OAI收割 [24]
• iSwitch采集 [3]

内容类型

• 期刊论文 [27]

发表日期

• 2024 [1]
• 2023 [1]
• 2022 [2]
• 2021 [2]
• 2016 [1]
• 2015 [2]
• 更多

学科主题

• Biochemist... [3]
• Biotechnol... [2]
• Biochemist... [1]
• Biophysics [1]
• Chemistry [1]
• Genetics &... [1]
• 更多

筛选

浏览/检索结果: 共27条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Interaction-Based Inductive Bias in Graph Neural Networks: Enhancing Protein-Ligand Binding Affinity Predictions From 3D Structures 期刊论文  OAI收割 IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2024, 卷号: 46, 期号: 12, 页码: 8191-8208 作者:  Yang, Ziduo;  Zhong, Weihe;  Lv, Qiujie;  Dong, Tiejun;  Chen, Guanxing   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/01/14 Proteins  Programmable logic arrays  Three-dimensional displays  Predictive models  Graph neural networks  Data models  Convolution  Protein-ligand binding affinity  graph neural networks  inductive bias  drug-target interaction  structure-based virtual screening   Intercellular Receptor-ligand Binding: Effect of Protein-membrane Interaction 期刊论文  OAI收割 JOURNAL OF MOLECULAR BIOLOGY, 2023, 卷号: 435, 期号: 1, 页码: 17 作者:  Li, Long;  Ji, Jing;  Song, Fan;  Hu, Jinglei;  Song F(宋凡)   |  收藏  |  浏览/下载：56/0  |  提交时间：2023/03/08 Protein-membrane interaction  Intercellular receptor-ligand binding  Membrane fluctuations and curvature  Glycocalyx  Lipid raft   2,2 ',4,4 '-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPAR gamma Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation 期刊论文  OAI收割 CHEMICAL RESEARCH IN TOXICOLOGY, 2022, 卷号: 35, 期号: 6, 页码: 1023-1035 作者:  Ren, Qidong;  Xie, Xinni;  Zhao, Chuanfang;  Wen, Qing;  Pan, Ruiying   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/11/08 ACTIVATED-RECEPTOR-GAMMA  BROMINATED FLAME RETARDANTS  ACID-BINDING PROTEIN  GENE-EXPRESSION  LIGAND-BINDING  DIPHENYL ETHERS  INDOOR DUST  EXPOSURE  CD36  ACCUMULATION   Insights into intercellular receptor-ligand binding kinetics in cell communication 期刊论文  OAI收割 FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 卷号: 10, 页码: 953353 作者:  An, Chenyi;  Wang, Xiaohuan;  Song F(宋凡);  Hu, Jinglei;  Li L(李龙)   |  收藏  |  浏览/下载：42/0  |  提交时间：2022/10/23 cell communication  intercellular receptor-ligand binding kinetics  protein-membrane interaction  biomechanical force  bioelectric microenvironment   CSConv2d: A 2-D Structural Convolution Neural Network with a Channel and Spatial Attention Mechanism for Protein-Ligand Binding Affinity Prediction 期刊论文  OAI收割 BIOMOLECULES, 2021, 卷号: 11, 期号: 5, 页码: 9 作者:  Wang, Xun;  Liu, Dayan;  Zhu, Jinfu;  Rodriguez-Paton, Alfonso;  Song, Tao   |  收藏  |  浏览/下载：62/0  |  提交时间：2021/12/01 protein-ligand binding affinity  2-D structural CNN  spatial attention mechanism   Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963 作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/04/02 Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN   Effects of ligand binding on the mechanical stability of protein GB1 studied by steered molecular dynamics simulation 期刊论文  OAI收割 JOURNAL OF MOLECULAR MODELING, 2016, 卷号: 22, 期号: 8 作者:  Su, JG;  Zhao, SX;  Wang XF(王晓峰);  Li JY(李敬源);  Wang, XF   |  收藏  |  浏览/下载：29/0  |  提交时间：2017/07/24 Protein mechanics  Mechanical unfolding  Allosteric regulation  Force-bearing  Ligand binding  Steered molecular dynamics simulation   Crystal structure of the Locusta migratoria odorant binding protein 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 卷号: 456, 期号: 3, 页码: 737-742 作者:  Zheng, JG;  Li, JR;  Han, L;  Wang, Y;  Wu, W 收藏  |  浏览/下载：15/0  |  提交时间：2016/04/18 Locusta migratoria  Odorant binding protein  Odorant perception  Crystal structure  Ligand binding mechanism   The Universal Statistical Distributions of the Affinity, Equilibrium Constants, Kinetics and Specificity in Biomolecular Recognition 期刊论文  OAI收割 plos computational biology, 2015, 卷号: 11, 期号: 4, 页码: 5493-5497 作者:  Zheng,Xiliang;  Wang,Jin 收藏  |  浏览/下载：31/0  |  提交时间：2016/05/12 SINGLE-MOLECULE DYNAMICS  RANDOM-ENERGY-MODEL  PROTEIN-FOLDING FUNNELS  3-HELIX BUNDLE PROTEIN  DRUG DISCOVERY  COMBINATORIAL TECHNOLOGIES  ENZYMATIC DYNAMICS  INTERFACE BINDING  LANDSCAPE MODEL  LIGAND-BINDING   Insights into the structure of class B GPCRs 期刊论文  OAI收割 TRENDS IN PHARMACOLOGICAL SCIENCES, 2014, 卷号: 35, 期号: 1, 页码: 12-22 作者:  Hollenstein, Kaspar;  de Graaf, Chris;  Bortolato, Andrea;  Wang, Ming-Wei;  Marshall, Fiona H.   |  收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 class B G protein-coupled receptor (GPCR)  glucagon receptor (GCGR)  corticotropin-releasing factor receptor 1 (CRF1)  crystal structure  ligand binding