中国科学院机构知识库网格系统: 检索

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	From bench to bedside: current development and emerging trend of KRAS-targeted therapy 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18 作者: Chen, Yi; Liu, Qiu-pei; Xie, Hua; Ding, Jian \| 收藏 \| 浏览/下载：54/0 \| 提交时间：2024/01/16 KRAS mutation KRAS(G12C) inhibitor Pan-KRAS inhibitor SHP2 allosteric inhibitor SOS1 inhibitor combination therapy
	Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 233, 页码: 13 作者: Tang, Qidong; Peng, Ting; Hu, Jie; Zhang, Tao; Chen, Pengqin \| 收藏 \| 浏览/下载：44/0 \| 提交时间：2022/08/16 Reversible irreversible pan-HER inhibitor Quinazolin-4-amine derivatives Anti-tumor Structure-activity relationship
	Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236 作者: Duan, Zhe; Liu, Jingqiu; Niu, Liping; Wang, Jun; Feng, Mingqian \| 收藏 \| 浏览/下载：38/0 \| 提交时间：2020/07/01 IDH1 mutation High-throughput screening Pan-inhibitor 2-HG Gliomas
	3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x(L) and Mcl-1 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 1, 页码: 11-20 作者: Song, Ting; Li, Xiangqian; Chang, Xilong; Liang, Xiaomeng; Zhao, Yan 收藏 \| 浏览/下载：39/0 \| 提交时间：2015/11/02 Pan-Bcl-2 inhibitor Bcl-2 Mcl-1 p4 Pocket Apoptosis
	New advances in isoform-selective inhibitors of Zn~(2+)-dependent histone deacetylase 期刊论文 OAI收割 Chinese Pharmacological Bulletin, 2010, 卷号: 26, 期号: 8, 页码: 985-989 作者: Liu Hongchun; Du Xiaoguang; Geng Meiyu \| 收藏 \| 浏览/下载：25/0 \| 提交时间：2019/01/08 histone deacetylase Zn~(2+)-dependent histone deacetylase isoform-selective inhibitor pan-inhibitor toxicity tumor