中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
上海营养与健康研究所 [2]
采集方式
OAI收割 [15]
内容类型
期刊论文 [15]
发表日期
2024 [2]
2023 [2]
2021 [2]
2020 [2]
2019 [3]
2018 [2]
更多
学科主题
Endocrinol... [1]
Life Scien... [1]
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共15条,第1-10条
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Amide alkaloids and neolignans from Piper hongkongense and their inhibitory activities of PCSK9 expression
期刊论文
OAI收割
FITOTERAPIA, 2024, 卷号: 175, 页码: 7
作者:
Hu, Xianggang
;
Chen, Tong
;
Guo, Pengju
;
Wang, Qing
;
Ding, Aoxue
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/06/27
Piper hongkongense
piper
Amide alkaloids
Neolignans
Inhibitory activities of PCSK9 expression
Lindenane sesquiterpenoid dimers from
Chloranthus
japonicus
improve LDL uptake by regulating PCSK9 and LDLR
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 142, 页码: 13
作者:
Guo, Pengju
;
Chen, Tong
;
Hu, Xianggang
;
Duan, Yelin
;
Zheng, Liu
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/01/16
Chloranthus japonicas
Lindenane sesquiterpenoid dimers
PCSK9
LDLR
Five undescribed abietane-type diterpenes of Callicarpa macrophylla
期刊论文
OAI收割
FITOTERAPIA, 2023, 卷号: 170, 页码: 10
作者:
Du, Gao-Xiang
;
Chen, Tong
;
Wang, Ge
;
Liu, Ying-Bo
;
Zheng, Liu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
Callicarpa macrophylla
Verbenaceae
Abietane-type diterpenoids
PCSK9
Macrophypene F -J
Ent- kaurane diterpenoids from Isodon japonica var. glaucocalyx with PCSK9 inhibitory activities
期刊论文
OAI收割
PHYTOCHEMISTRY LETTERS, 2023, 卷号: 57, 页码: 56-61
作者:
Wang, Ge
;
Chen, Tong
;
Guo, Peng-Ju
;
Peng, Shou
;
Wang, Wen-Qiong
  |  
收藏
  |  
浏览/下载:257/0
  |  
提交时间:2023/10/17
Purine-diterpenoid derivatives
Ent -kaurane diterpenoid
PCSK9 inhibition activity
MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice
期刊论文
OAI收割
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 119, 页码: 12
作者:
Xu, Xiaoding
;
Dong, Yunxia
;
Ma, Ningning
;
Kong, Weiwen
;
Yu, Chuwei
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/08/17
miR-337-3p
PCSK9
LDL-C
Hyperlipidemia
Dual regulation
New PCSK9 inhibitor miR-552-3p reduces LDL-C via enhancing LDLR in high fat diet-fed mice
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 167, 页码: 13
作者:
Ma, Ningning
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/08/17
PCSK9
Hyperlipidemia
MiR-552-3p
3 '-UTR
Promoter
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:
Li, Hui-hui
;
Li, Jun
;
Zhang, Xian-jing
;
Li, Jiao-meng
;
Xi, Cong
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
23,24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1 alpha
SREBP2
pcsk9与多种代谢相关疾病发生发展关系的研究进展
期刊论文
OAI收割
中国新药杂志, 2020, 卷号: 29, 期号: 5, 页码: 507
作者:
范磊
;
陈静
;
任进
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
PCSK9
diabetes
Alzheimer's disease
nonalcoholic fatty liver disease
tumor
PCSK9
糖尿病
阿尔茨海默症
非酒精性脂肪肝病
肿瘤
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia
期刊论文
OAI收割
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:
Wu Chenglin
;
Xi Cong
;
Tong Junhua
;
Zhao Jing
;
Jiang Hualiang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
DOPAMINE D-1
BERBERINE
EXPRESSION
INHIBITORS
IDENTIFICATION
CHOLESTEROL
MUTATIONS
LDLR
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster