中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1
期刊论文
OAI收割
出版物, 2111, 页码: 1-44
作者:
1M S Grace
;
T Lieu
;
B Darby
;
F C Abogadie
;
N Veldhuis N W Bunnett
;
P McIntyre
  |  
收藏
  |  
浏览/下载:226/0
  |  
提交时间:2017/07/24
Transient Receptor Potential Ion Channel
Trpv4
Protease Activated Receptor
Par2
Pain
Tyrosine Kinase
Bafetinib
Chemical Space Profiling of SARS-CoV-2 PL
pro
Using DNA-Encoded Focused Libraries
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 10
作者:
Wang, Xudong
;
Zhu, Ying
;
Zhao, Qingyi
;
Lu, Weiwei
;
Xu, Yechun
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
DNA-Encoded Focused Libraries (DEFLs)
SARS-CoV-2
Papain-like Protease
Library Design
ProteinInhibitors
Expression patterns and antifungal function study of KaSPI in
Mythimna separata
期刊论文
OAI收割
BULLETIN OF ENTOMOLOGICAL RESEARCH, 2023, 页码: 11
作者:
Chen, Ya-Ru
;
Yang, Hong-Jia
;
Cha, Jin-Myong
;
Zhang, Xin-Xin
;
Fan, Dong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/07
Beauveria bassiana
enzyme activity
Mythimna separata
RNA interference
serine protease inhibitor
Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial
期刊论文
OAI收割
LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13
作者:
Wang, Fuxiang
;
Xiao, Wen
;
Tang, Yimin
;
Cao, Mengli
;
Shu, Dan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
Covid-19
3CL protease inhibitor
SARS-CoV-2 viral load
Alleviation of COVID-19 symptoms
Preparation and characterization of nanobodies targeting SARS-CoV-2 papain-like protease
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106267
作者:
Qiao, Huarui
;
Li, Lingyun
;
Wang, Lu
;
Yu, Haijun
;
Hu, Fangzheng
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
SARS-CoV-2
Papain like protease (PLpro)
Nanobody
PLpro inhibitor
Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15
作者:
Wang, Qian
;
Chen, Guofeng
;
He, Jian
;
Li, Jiameng
;
Xiong, Muya
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
SARS-CoV-2
papain-like protease
covalent inhibitor
co-crystal structure
in vitro assay
Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12
作者:
Zhu, Mengwei
;
Fu, Tiantian
;
You, Mengyuan
;
Cao, Junyuan
;
Yang, Hanxi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
COVID-19
SARS-CoV-2
3CL protease
Nirmatrelvir
Peptidomimetic inhibitors
Spatial-Drug-Laden Protease-Activatable M1 Macrophage System Targets Lung Metastasis and Potentiates Antitumor Immunity
期刊论文
OAI收割
ACS NANO, 2023, 卷号: 17, 期号: 6, 页码: 5354-5372
作者:
Xu, Xiaoxuan
;
Wang, Qiang
;
Qian, Xindi
;
Wu, Yao
;
Wang, Jiaoying
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
M1 macrophages
lung metastasis
antitumor immunity
fibroblast activation protein protease
liposome
Discovery of Polyphenolic Natural Products as SARS-CoV-2 Mpro Inhibitors for COVID-19
期刊论文
OAI收割
PHARMACEUTICALS, 2023, 卷号: 16, 期号: 2, 页码: 190
作者:
Kruger, Nadine
;
Kronenberger, Thales
;
Xie, Hang
;
Rocha, Cheila
;
Pohlmann, Stefan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
antivirals
coronavirus
COVID-19
covalent drugs
dynamic light scattering
inhibitors
main protease
natural products
Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis
期刊论文
OAI收割
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 卷号: 43, 期号: 2, 页码: 253-266
作者:
Li,Sujuan
;
Wang,Weili
;
Lin,Lisha
;
Yang,Lian
;
Cai,Ying
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/09
oligosaccharide
platelet activation
receptor
protease-activated
thrombin thrombosis
ANTIPLATELET THERAPIES
ALLOSTERIC LINKAGE
TISSUE FACTOR
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