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浏览/检索结果: 共243条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文  OAI收割 出版物, 2111, 页码: 1-44 作者:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre   |  收藏  |  浏览/下载：249/0  |  提交时间：2017/07/24 Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib   Research progress on critical viral protease inhibitors for coronaviruses and enteroviruses 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 122, 页码: 19 作者:  Hu, Shulei;  Zhong, Qiuyu;  Xie, Xiong;  Zhang, Shurui;  Wang, Jinlin   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/05/27 Innate immunity response  SARS-CoV-2 3CLpro  PLpro  EV71 3Cpro  2Apro  Viral protease inhibitor   Strategic Amino Acid Mutations in CPD Cleavage Motif: Impacts on Hydrolysis and C-Terminal Modification Efficiency 期刊论文  OAI收割 CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2025, 卷号: 41, 期号: 3, 页码: 592-600 作者:  Yashinov, Ansor;  Zou, Xiangman;  Hang, Jiayin;  Liu, Zhi;  Song, Fengnan   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/06/23 Protein engineering  C-Terminal modification  Cysteine protease domain  Self-cleavage tag  AlphaFold2   Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796 作者:  Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei;  Cui, Wenjie   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/06/23 COVID-19  SARS-CoV-2  3CL protease  Peptidomimetic inhibitors  Tetrahydropyrrole spirodihydroindolone   Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease 期刊论文  OAI收割 ADVANCED SCIENCE, 2025, 页码: 13 作者:  Su, Haixia;  Wu, Guoqing;  Xiong, Muya;  Wang, Yuhang;  Cao, Junyuan   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/05/27 covalent inhibitors  I7L protease  monkeypox virus  protein structures  substrate proteolysis   Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248 作者:  Wang, Yingying;  Zhang, Youping;  Luo, Hao;  Wei, Wei;  Liu, Wanting   |  收藏  |  浏览/下载：20/0  |  提交时间：2025/04/01 Ubiquitin-specific protease 2  KRAS  Gambogic acid  Multiple myeloma  Degradation  Ubiquitination  Allosteric pocket  Deubiquitination   Structural Basis of Main Proteases of Coronavirus Bound to Bofutrelvir 期刊论文  OAI收割 JOURNAL OF MOLECULAR BIOLOGY, 2024, 卷号: 436, 期号: 22, 页码: 16 作者:  Wang, Wei-wei;  Zeng, Pei;  Liu, Tongchao;  Zhou, Xue-lan;  Lin, Cheng   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/10/21 SARS-CoV-2  Coronavirus  Main protease  Mutants  Inhibitor   DNA-Encoded Noncanonical Substrate Library for Protease Profiling 期刊论文  OAI收割 CHEMBIOCHEM, 2024, 页码: 12 作者:  Zhang, Huiya;  Xing, Yuyu;  Yang, Yixuan;  Tang, Bixi;  Zong, Zhaoyun   |  收藏  |  浏览/下载：81/0  |  提交时间：2024/12/16 Protease substrate  DNA-encoded library  Combinatorial peptide library  High-throughput screening  Covalent inhibitor  Noncanonical peptide   Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 21 作者:  Lu, Yang;  Gao, Jian;  Wang, Peipei;  Chen, Haifeng;  He, Xinjun   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/07/12 Hepatocellular carcinoma  Ubiquitin-specific protease 10  Deubiquitination  Selectivity   Chemical Space Profiling of SARS-CoV-2 PLpro Using DNA-Encoded Focused Libraries 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 10 作者:  Wang, Xudong;  Zhu, Ying;  Zhao, Qingyi;  Lu, Weiwei;  Xu, Yechun   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/05/07 DNA-Encoded Focused Libraries (DEFLs)  SARS-CoV-2  Papain-like Protease  Library Design  ProteinInhibitors