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The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1
期刊论文
OAI收割
出版物, 2111, 页码: 1-44
作者:
1M S Grace
;
T Lieu
;
B Darby
;
F C Abogadie
;
N Veldhuis N W Bunnett
;
P McIntyre
  |  
收藏
  |  
浏览/下载:244/0
  |  
提交时间:2017/07/24
Transient Receptor Potential Ion Channel
Trpv4
Protease Activated Receptor
Par2
Pain
Tyrosine Kinase
Bafetinib
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248
作者:
Wang, Yingying
;
Zhang, Youping
;
Luo, Hao
;
Wei, Wei
;
Liu, Wanting
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
Ubiquitin-specific protease 2
KRAS
Gambogic acid
Multiple myeloma
Degradation
Ubiquitination
Allosteric pocket
Deubiquitination
Structural Basis of Main Proteases of Coronavirus Bound to Bofutrelvir
期刊论文
OAI收割
JOURNAL OF MOLECULAR BIOLOGY, 2024, 卷号: 436, 期号: 22, 页码: 16
作者:
Wang, Wei-wei
;
Zeng, Pei
;
Liu, Tongchao
;
Zhou, Xue-lan
;
Lin, Cheng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/10/21
SARS-CoV-2
Coronavirus
Main protease
Mutants
Inhibitor
DNA-Encoded Noncanonical Substrate Library for Protease Profiling
期刊论文
OAI收割
CHEMBIOCHEM, 2024, 页码: 12
作者:
Zhang, Huiya
;
Xing, Yuyu
;
Yang, Yixuan
;
Tang, Bixi
;
Zong, Zhaoyun
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2024/12/16
Protease substrate
DNA-encoded library
Combinatorial peptide library
High-throughput screening
Covalent inhibitor
Noncanonical peptide
Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 21
作者:
Lu, Yang
;
Gao, Jian
;
Wang, Peipei
;
Chen, Haifeng
;
He, Xinjun
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/07/12
Hepatocellular carcinoma
Ubiquitin-specific protease 10
Deubiquitination
Selectivity
Chemical Space Profiling of SARS-CoV-2 PL
pro
Using DNA-Encoded Focused Libraries
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 10
作者:
Wang, Xudong
;
Zhu, Ying
;
Zhao, Qingyi
;
Lu, Weiwei
;
Xu, Yechun
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/05/07
DNA-Encoded Focused Libraries (DEFLs)
SARS-CoV-2
Papain-like Protease
Library Design
ProteinInhibitors
Soil biomass-related enzyme activity indicates minimal functional changes after 16 years of persistent drought treatment in a Mediterranean holm oak forest
期刊论文
OAI收割
SOIL BIOLOGY & BIOCHEMISTRY, 2024, 卷号: 189, 页码: 12
作者:
Asensio, Dolores
;
Zuccarini, Paolo
;
Sardans, Jordi
;
Maranon-Jimenez, Sara
;
Mattana, Stefania
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/09/12
Acid and alkaline phosphatases
Beta-glucosidase
Climate change
Drought
Drought-resistance
Mediterranean holm oak forest
Microbial functional adaptation
Phosphorus
Protease
Soil enzymes
Urease
Expression patterns and antifungal function study of KaSPI in
Mythimna separata
期刊论文
OAI收割
BULLETIN OF ENTOMOLOGICAL RESEARCH, 2023, 页码: 11
作者:
Chen, Ya-Ru
;
Yang, Hong-Jia
;
Cha, Jin-Myong
;
Zhang, Xin-Xin
;
Fan, Dong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/12/07
Beauveria bassiana
enzyme activity
Mythimna separata
RNA interference
serine protease inhibitor
Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial
期刊论文
OAI收割
LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13
作者:
Wang, Fuxiang
;
Xiao, Wen
;
Tang, Yimin
;
Cao, Mengli
;
Shu, Dan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
Covid-19
3CL protease inhibitor
SARS-CoV-2 viral load
Alleviation of COVID-19 symptoms
Preparation and characterization of nanobodies targeting SARS-CoV-2 papain-like protease
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106267
作者:
Qiao, Huarui
;
Li, Lingyun
;
Wang, Lu
;
Yu, Haijun
;
Hu, Fangzheng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/27
SARS-CoV-2
Papain like protease (PLpro)
Nanobody
PLpro inhibitor