中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [30]
上海生物化学与细胞... [10]
昆明植物研究所 [7]
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期刊论文 [114]
会议论文 [1]
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Biochemis... [11]
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浏览/检索结果:
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BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair
期刊论文
OAI收割
TRANSLATIONAL ONCOLOGY, 2025, 卷号: 51, 页码: 11
作者:
Chi, Shuaishuai
;
Wei, Fan
;
Li, Yangsha
;
Yu, Lei
;
Ma, Chuyao
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/01/06
CDK4
BRD4
Breast cancer
Protein stability
DNA damage
Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 16
作者:
An, Yuxiang
;
Peng, Xia
;
Wang, Tianchen
;
Liu, Kaiyuan
;
Feng, Dazhi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/25
inhibitor
pharmacokinetic study
pyridazin-4-one
receptor-interacting protein kinase 1
selectivity
Amlodipine inhibits Synaptotagmin-4's oncogenic activity on gastric cancer proliferation by targeting calcium signaling
期刊论文
OAI收割
FUNCTIONAL & INTEGRATIVE GENOMICS, 2024, 卷号: 24, 期号: 3, 页码: 14
作者:
Huang, Wen
;
Yang, Shuo
;
Deng, Minying
;
Luo, Rongkui
;
Liang, Huaiyu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/22
Gastric cancer
synaptotagmin-4
Calcium ion channel
Mitogen-activated protein kinase signaling pathway
Amlodipine
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
;
Li, Mengyue
;
Xu, Dehua
;
Zhang, Laishun
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
Horizontally acquired fungal killer protein genes affect cell development in mosses
期刊论文
OAI收割
PLANT JOURNAL, 2023
作者:
Guan,Yanlong
;
Ma,Lan
;
Wang,Qia
;
Zhao,Jinjie
;
Wang,Shuanghua
  |  
收藏
  |  
浏览/下载:212/0
  |  
提交时间:2024/07/10
horizontal gene transfer
Physcomitrium patens
killer protein 4
plant evolution
cytoplasmic calcium
cell death
PHYSCOMITRELLA-PATENS
CALCIUM-CHANNELS
USTILAGO-MAYDIS
PLANT
LAND
GROWTH
TOXIN
APOPTOSIS
INSIGHTS
GENOMES
PDE4B Induces Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Is Transcriptionally Suppressed by CBX7
期刊论文
OAI收割
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9, 页码: 12
作者:
Huang, Zhengnan
;
Liu, Jiakuan
;
Yang, Jiale
;
Yan, Yilin
;
Yang, Chenkai
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/06/15
phosphodiesterase 4B
urinary bladder cancer
chromobox protein homolog 7
epithelial-to-mesenchymal transition
beta-catenin
Rational Design of a Miniature Photocatalytic CO2-Reducing Enzyme
期刊论文
OAI收割
ACS CATALYSIS, 2021, 卷号: 11
作者:
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收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/08/31
photosystem I
rational design
photosensitizer protein
iron-sulfur (Fe4S4) cluster
photocatalytic
CO2 reductase
Structural Determinants for Light-Dependent Membrane Binding of a Photoswitchable Polybasic Domain
期刊论文
OAI收割
ACS SYNTHETIC BIOLOGY, 2021, 卷号: 10
作者:
Li, Ling
;
He, Lian
;
Wu, Bo
;
Yu, Chuandi
;
Zhao, Hongxin
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/04/26
polybasic domain
LOV2
optogenetics
NMR
PI(4,5)P-2
protein-lipid interaction
Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 1, 页码: 82-87
作者:
Chen, Yun
;
Ning, Yi
;
Bai, Gang
;
Tong, Linjiang
;
Zhang, Tao
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2021/05/24
IRAK4
PROTAC
protein degrader
scaffolding role
diffuse large B-cell lymphoma
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review
期刊论文
OAI收割
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:
Zhang, Jiajia
;
Wu, Ning
;
Shi, Dayong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/05/11
Signaling pathway
mammalian target of rapamycin
protein tyrosine phosphatase 1b
dipeptidase 4
cancer
diabetes
pharmacology
target compounds