中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
金属研究所 [2]
生物物理研究所 [1]
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OAI收割 [13]
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期刊论文 [13]
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2019 [1]
2017 [1]
2015 [1]
2014 [3]
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Biochemist... [1]
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Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas
期刊论文
OAI收割
BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13
作者:
Zhang, Qing
;
Liu, Jian-He
;
Liu, Jing-Li
;
Qi, Chun-Ting
;
Yan, Lei
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2020/07/01
Receptor tyrosine kinases (RTKs)
Activation and function
Clear cell renal cell carcinomas (ccRCCs)
Targeted therapy
PDGFR beta
Stroma cells
Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells
期刊论文
OAI收割
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 5003-5015
作者:
Song, Qiaoling
;
Sun, Xiaoxiao
;
Guo, Hui
;
Yu, Qiang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
receptor tyrosine kinases
AKT
colorectal cancer
drug combination
RAS/RAF
Design, Synthesis and Antitumor Activity of Novel 6,7-Dimethoxyquinazoline Derivatives Containing Diaryl Urea Moiety
期刊论文
OAI收割
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2015, 卷号: 31, 期号: 5, 页码: 766-773
作者:
Hou Yunlei
;
Wu Shasha
;
Ma Longsheng
;
Bai Jinying
;
Liu Zijian
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/02/02
RECEPTOR TYROSINE KINASES
BIOLOGICAL EVALUATION
HIGHLY POTENT
INHIBITOR
IDENTIFICATION
GROWTH
DISCOVERY
SORAFENIB
EGFR
6,7-Dimethoxyquinazoline derivative
Diaryl urea scaffold
Cytotoxic activity
HSP90 inhibitor AUY922 abrogates up-regulation of RTKs by mTOR inhibitor AZD8055 and potentiates its antiproliferative activity in human breast cancer
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF CANCER, 2014, 卷号: 135, 期号: 10, 页码: 2462-2474
作者:
Chen, Si-Meng
;
Guo, Chen-Liang
;
Shi, Jia-Jie
;
Xu, Yi-Chao
;
Chen, Yi
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
mTOR kinase inhibitor
HSP90 inhibitor
breast cancer
receptor tyrosine kinases
drug combination
Chemical Constituents from the Heartwood of Haematoxylon campechianum as Protein Tyrosine Kinase Inhibitors
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2014, 卷号: 11, 期号: 5, 页码: 776-783
作者:
Lin, Li-Gen
;
Xie, Hua
;
Wang, Yi-Tao
;
Ding, Jian
;
Ye, Yang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Haematoxylon campechianum
Protein tyrosine kinases (PTKs)
Epihematoxylol B
Homoisoflavonoids
Hematoxylol B
10-O-methyl-
Kinase insert domain receptor (KDR)
Aqueous extract of Taxus Chinensis (Pilger) Rehd inhibits lung carcinoma A549 cells through the epidermal growth factor receptor/mitogen-activated protein kinase pathway in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF TRADITIONAL CHINESE MEDICINE, 2014, 卷号: 34
-
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/10/26
PHARMACOLOGICAL TESTING METHOD
VAR. MAIREI
TYROSINE PHOSPHORYLATION
HUMAN TUMORS
CANCER
EXPRESSION
THERAPY
MAPK
PROLIFERATION
Taxus
Lung neoplasms
Receptor
epidermal growth factor
Mitogen-activated protein kinases
In vitro
In vivo
The Design and Synthesis of a New Class of RTK/HDAC Dual-Targeted Inhibitors
期刊论文
OAI收割
MOLECULES, 2013, 卷号: 18, 期号: 6, 页码: 6491-6503
作者:
Zhang, Xuan
;
Su, Mingbo
;
Chen, Yi
;
Li, Jia
;
Lu, Wei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
receptor tyrosine kinases
histone deacetylase
antitumor
synergistic effect
dual inhibitor
Synthesis and in vitro antitumor activity of novel diaryl urea derivatives
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2013, 卷号: 24, 期号: 5, 页码: 386-388
作者:
Zhao YanFang
;
Liu ZiJian
;
Zhai Xin
;
Ge DanDan
;
Huang Qiang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/02/26
RECEPTOR TYROSINE KINASES
INHIBITOR
DISCOVERY
SORAFENIB
Diaryl ureas
Synthesis
Antitumor activity in vitro
Effects of Paclitaxel on EGFR Endocytic Trafficking Revealed Using Quantum Dot Tracking in Single Cells
期刊论文
OAI收割
PLOS ONE, 2012, 卷号: 7, 期号: 9
Li, H
;
Duan, ZW
;
Xie, P
;
Liu, YR
;
Wang, WC
;
Dou, SX
;
Wang, PY
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2013/09/17
EPIDERMAL GROWTH-FACTOR
CLATHRIN-MEDIATED ENDOCYTOSIS
RECEPTOR TYROSINE KINASES
LIVING CELLS
LIVE CELLS
INTERMEDIATE-FILAMENTS
AXONAL-TRANSPORT
ERBB RECEPTORS
A431 CELLS
TAXOL
Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis
期刊论文
OAI收割
ONCOGENE, 2009, 卷号: 28, 期号: 16, 页码: 1853-1863
Qin, J
;
Xie, Y
;
wang, b
;
王波
;
Hoshino, M
;
Wolff, D W
;
Zhao, J
;
Scofield, M A
;
Dowd, F J
;
Lin, MF
;
Tu, Y
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2013/12/25
prostate cancer metastasis
P-Rex1
Rac-selective guanine nucleotide exchange factor
G-protein-coupled receptors
receptor tyrosine kinases