中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [21]
上海营养与健康研究所 [5]
金属研究所 [3]
大连化学物理研究所 [2]
中国科学院大学 [2]
海洋研究所 [2]
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OAI收割 [38]
iSwitch采集 [2]
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期刊论文 [32]
会议论文 [4]
学位论文 [4]
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2024 [1]
2022 [2]
2020 [1]
2018 [1]
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Pharmacolo... [2]
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Vitamin D Relieves Epilepsy Symptoms and Neuroinflammation in Juvenile Mice by Activating the mTOR Signaling Pathway via RAF1: Insights from Network Pharmacology and Molecular Docking Studies
期刊论文
OAI收割
NEUROCHEMICAL RESEARCH, 2024, 页码: 14
作者:
Lu, Tiantian
;
Chen, Xiuling
;
Zhang, Qin
;
Shang, Kun
;
Yang, Xiaogui
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/10/21
Epilepsy
Neuroinflammation
Vitamin D
RAF1
mTOR signaling pathway
Network pharmacology
Molecular docking
The Agonist of Adenosine A1 Receptor Induced Desensitization of delta Opioid receptor-mediated Raf-1/MEK/ERK Signaling by Feedback Phosphorylation of Raf-1-Ser289/296/301
期刊论文
OAI收割
NEUROCHEMICAL RESEARCH, 2022, 页码: 12
作者:
Xu, Chi
;
Cheng, Yun
;
Han, Manman
;
Tao, Yimin
;
Liu, Jing-Gen
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/04/10
Adenosine A1 receptor
N6-cyclohexyladenosine
Delta opioid receptor
Raf-1
Desensitization
A homogalacturonan from Lonicera japonica Thunb. disrupts angiogenesis via epidermal growth factor receptor and Delta-like 4 associated signaling
期刊论文
OAI收割
GLYCOCONJUGATE JOURNAL, 2022, 页码: 11
作者:
Liao, Wenfeng
;
Hu, Xiaodong
;
Du, Zhenyun
;
Wang, Peipei
;
Ding, Kan
  |  
收藏
  |  
浏览/下载:128/0
  |  
提交时间:2022/12/13
Homogalacturonan
Angiogenesis
Lonicera japonica
EGFR/Raf/MEK/ERK signaling cascade
Dll4/Notch1 signaling
EPHA2 feedback activation limits the response to PDE delta inhibition in KRAS-dependent cancer cells
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 270-277
作者:
Chen, Yue-hong
;
Lv, Hao
;
Shen, Ning
;
Wang, Xiao-min
;
Tang, Shuai
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
KRAS
anticancer therapy
PDE delta
EPHA2
RAF
MEK
ERK signaling
Identification of recurrent USP48 and BRAF mutations in Cushing's disease
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2018, 卷号: 9, 期号: 1, 页码: 3171
作者:
Chen, Jianhua
;
Jian, Xuemin
;
Song, Zhijian
;
Li, Zhiqiang
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/04/28
Human Cancer
Proopiomelanocortin Gene
Deubiquitinating Enzyme
Pituitary-adenomas
Kappa-b
Transcription
Activation
Raf
Pathways
Genome
Virtual screening of B-Raf kinase inhibitors: A combination of pharmacophore modelling, molecular docking, 3D-QSAR model and binding free energy calculation studies
期刊论文
OAI收割
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2017, 卷号: 70, 页码: 186-190
作者:
Zhang, Wen
;
Qiu, Kai-Xiong
;
Yu, Fang
;
Xie, Xiao-Guang
;
Zhang, Shu-Qun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2017/12/11
B-raf Kinase Inhibitors
Virtual Screening
Pharmacophore
Molecular Docking
3d Qsar
Binding Free Energy Calculation
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf(V600E) inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1059-1068
作者:
Wang, Gui-min
;
Wang, Xiang
;
Zhu, Jian-ming
;
Guo, Bin-bin
;
Yang, Zhuo
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
B-Raf(V600E) inhibitor
anticancer
vemurafenib
deazapurine
fragment reassembly
molecular docking
structure-activity relationship
Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells
期刊论文
OAI收割
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 5003-5015
作者:
Song, Qiaoling
;
Sun, Xiaoxiao
;
Guo, Hui
;
Yu, Qiang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
receptor tyrosine kinases
AKT
colorectal cancer
drug combination
RAS/RAF
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf~(V600E) inhibitors
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 7, 页码: 1057-1068
作者:
Wang Guimin
;
Wang Xiang
;
Zhu Jianming
;
Guo Binbin
;
Yang Zhuo
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
B-Raf~(V600E) inhibitor
anticancer
vemurafenib
deazapurine
fragment reassembly
molecular docking
structure-activity relationship
Cellular model of neuronal atrophy induced by dync1i1 deficiency reveals protective roles of ras-raf-mek signaling
期刊论文
iSwitch采集
Protein & cell, 2016, 卷号: 7, 期号: 9, 页码: 638-650
作者:
Liu, Zhi-Dong
;
Zhang, Su
;
Hao, Jian-Jin
;
Xie, Tao-Rong
;
Kang, Jian-Sheng
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/05/09
Ras-raf-mek pathway
Atrophy
Dynein intermediate chain
Mitochondria
Hippocampal neuron
Autophagy