中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [21]
昆明植物研究所 [5]
福建物质结构研究所 [2]
成都生物研究所 [1]
大连化学物理研究所 [1]
心理研究所 [1]
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OAI收割 [33]
内容类型
期刊论文 [33]
发表日期
2023 [1]
2022 [3]
2021 [4]
2020 [1]
2019 [3]
2018 [2]
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学科主题
Chemistry [3]
Pharmacolo... [3]
Biochemist... [1]
Chemistry,... [1]
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浏览/检索结果:
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Discovery of selective NaV1.8 inhibitors based on 5-chloro-2-(4,4-difluor- oazepan-1-yl)-6-methyl nicotinamide scaffold for the treatment of pain
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 12
作者:
Qin, Hui
;
Wei, Aihuan
;
Wang, Yunqi
;
Wang, Linlin
;
Xu, Haiyan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/10/17
Pain
Non-addictive analgesics
Na V 1
8-selective inhibitors
Bicyclic aromatic groups
Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural Products and Bioprospecting, 2022, 卷号: 12, 期号: 1
作者:
Deng,Xu
;
Huang,Su-Ling
;
Ren,Jian
;
Pan,Zheng-Hong
;
Shen,Yu
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/11/11
Metabolic syndrome
Tanshinones
Selective 11β-HSD1 inhibitors
Structure–activity relationships
Development and structure-activity relationships of tanshinones as selective 11beta-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural products and bioprospecting, 2022, 卷号: 12, 期号: 1, 页码: 36
作者:
Deng, Xu
;
Huang, Su-Ling
;
Ren, Jian
;
Pan, Zheng-Hong
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/03/15
Metabolic syndrome
Selective 11beta-HSD1 inhibitors
Structure-activity relationships
Tanshinones
Development and structure-activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
NATURAL PRODUCTS AND BIOPROSPECTING, 2022, 卷号: 12, 期号: 6, 页码: 1
作者:
Deng Xu
;
Huang Suling
;
Ren Jian
;
Pan Zhenghong
;
Shen Yu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/05/22
Metabolic syndrome
Tanshinones
Selective 11β-HSD1 inhibitors
Structure-activity relationships
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:
Chen, Jingjing
;
Li, Yalei
;
Zhang, Jie
;
Zhang, Minmin
;
Wei, Aihuan
  |  
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2021/05/24
HDAC
BRD4
Selective dual inhibitors
Anticancer
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
作者:
Huang,Qian
;
Chen,Ji-Jun
;
Pan,Yang
;
He,Xiao-Feng
;
Wang,Yuan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/04/02
Paeonia delavayi
Chemical comparison
LCMS analyses
Antidiabetic effects
PTP1B/TCPTP selective inhibitors
LIQUID-CHROMATOGRAPHY
MULTIPLE CONSTITUENTS
RAPID IDENTIFICATION
GLYCOSIDES
ROOT
DERIVATIVES
TARGETS
CAPSULE
L.
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Li,Tian-Ze
;
Hu,Jing
;
Zhang,Xue-Mei
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/04/02
Alpinia katsumadai
Katsumadainols A(1)-A(16)
PTP1B/TCPTP selective inhibitors
alpha-glucosidase inhibitors
Antidiabetic effects
THEORETICAL CALCULATION
ABSOLUTE-CONFIGURATION
SEEDS
BLEPHAROCALYXINS
ADDUCT
MOIETY
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors
期刊论文
OAI收割
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Huang,Xiao-Yan
;
Hu,Jing
;
Zhang,Xu-Ke
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2022/04/02
Amomum tsao-ko
Amomutsaokins A-H
Flavanol-menthane conjugates
PTP1B selective inhibitors
alpha-Glucosidase inhibitors
ANTIOXIDANT ACTIVITY
ESSENTIAL OIL
CONSTITUENTS
TANNINS
CREVOST
ACID
Factor analysis of electroacupuncture and selective serotonin reuptake inhibitors for major depressive disorder: an 8-week controlled clinical trial
期刊论文
OAI收割
ACUPUNCTURE IN MEDICINE, 2020, 卷号: 38, 期号: 1, 页码: 45-52
作者:
Yang, Xinjing
;
Gong, Weijun
;
Ma, Xuehong
;
Wang, Sihan
;
Wang, Xueqin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/03/30
electroacupuncture
major depressive disorder
Hamilton depression rating scale
anxiety
somatisation
selective serotonin reuptake inhibitors
Identification and characterization of potent and selective inhibitors targeting protein tyrosine phosphatase 1B (PTP1B)
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 16, 页码: 2358-2363
作者:
Jin, Jia
;
Ye, Xiaoqing
;
Boateng, Derrick
;
Dai, Kaili
;
Ye, Fei
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/21
PTP1B
TCPTP
Type 2 diabetes
Selective inhibitors
Dihydropyridine thione