机构

• 上海药物研究所 [4]
• 昆明植物研究所 [4]
• 海洋研究所 [3]

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [11]

发表日期

• 2021 [4]
• 2019 [1]
• 2018 [1]
• 2017 [2]
• 2016 [1]
• 2015 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063 作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan   |  收藏  |  浏览/下载：15/0  |  提交时间：2022/04/02 Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE   Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998 作者:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan   |  收藏  |  浏览/下载：12/0  |  提交时间：2022/04/02 Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.   Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683 作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei   |  收藏  |  浏览/下载：11/0  |  提交时间：2022/04/02 Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY   The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文  OAI收割 INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908 作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke   |  收藏  |  浏览/下载：20/0  |  提交时间：2022/04/02 Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID   Identification and characterization of potent and selective inhibitors targeting protein tyrosine phosphatase 1B (PTP1B) 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 16, 页码: 2358-2363 作者:  Jin, Jia;  Ye, Xiaoqing;  Boateng, Derrick;  Dai, Kaili;  Ye, Fei   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/03/21 PTP1B  TCPTP  Type 2 diabetes  Selective inhibitors  Dihydropyridine thione   Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 692-700 作者:  Du, Yongli;  Zhang, Yanhui;  Ling, Hao;  Li, Qunyi;  Shen, Jingkang   |  收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Protein tyrosine phosphatase 1B inhibitors  N-(2,5-diethoxy-phenyl)-methane sulfonamide  Type 2 diabetes mellitus  PTP1B   Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359 作者:  Li, Xiang-Qian;  Xu, Qi;  Luo, Jiao;  Wang, Li-Jun;  Jiang, Bo   |  收藏  |  浏览/下载：24/0  |  提交时间：2017/10/09 Type 2 Diabetes  Ptp1b Inhibition  Selectivity  Competitive  Cellular Activity   Discovery and evaluation of the hybrid of bromophenol and saccharide as potent and selective protein tyrosine phosphatase 1B inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 24-33 作者:  Zhang, Renshuai;  Yu, Rilei;  Xu, Qi;  Li, Xiangqian;  Luo, Jiao 收藏  |  浏览/下载：22/0  |  提交时间：2017/07/10 PTP1B  Bromophenol  Saccharide  Selectivity  Permeability   The design strategy of selective PTP1B inhibitors over TCPTP 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 16, 页码: 3343-3352 作者:  Li, XiangQian;  Wang, LiJun;  Shi, DaYong 收藏  |  浏览/下载：10/0  |  提交时间：2016/12/05 Selectivity  PTP1B inhibitor  TCPTP  Diabetes  Design strategy   Novel, potent, selective and cellular active ABC type PTP1B inhibitors containing (methanesulfonyl-phenyl-amino)-acetic acid methyl ester phosphotyrosine mimetic 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 21, 页码: 7079-7088 作者:  Liu, Peihong;  Du, Yongli;  Song, Lianhua;  Shen, Jingkang;  Li, Qunyi   |  收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 Type 2 diabetes mellitus  PTP1B  Inhibitor  Structure-activity relationships