中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
海洋研究所 [3]
昆明植物研究所 [2]
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上海应用物理研究所 [1]
长春应用化学研究所 [1]
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OAI收割 [18]
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期刊论文 [17]
CNKI期刊论文 [1]
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2023 [1]
2021 [2]
2019 [1]
2018 [1]
2017 [1]
2015 [3]
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Defensive Specialized Metabolites from the Latex of Euphorbia jolkinii
期刊论文
OAI收割
JOURNAL OF CHEMICAL ECOLOGY, 2023
作者:
Luo,Shihong
;
Huang,Chunshuai
;
Hua,Juan
;
Jing,Shuxi
;
Teng,Linlin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/05/09
Plant latex
Euphorbia jolkinii
meta-Tyrosine
Phytotoxic activity
Specialized metabolites
PLANT LATEX
META-TYROSINE
DITERPENOIDS
ROOTS
ACID
DERIVATIVES
COMPONENTS
GLYCOSIDE
FRUIT
Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1)
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:
Yu Lijie
;
Feng Bo
;
Wang Zhijia
;
Gao Lixin
;
Zhang Chun
  |  
收藏
  |  
浏览/下载:117/0
  |  
提交时间:2021/11/04
5-phenyl-1,3,4-thiadiazole derivatives
Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP1)
inhibitors
structure-activity relationships
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:
He,Xiao-Feng
;
Chen,Ji-Jun
;
Li,Tian-Ze
;
Hu,Jing
;
Huang,Xiao-Yan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/04/02
Alpinia katsumadai
Katsumadainols B-1-B-15
Natural products
Structure elucidation
Biological activity
TYROSINE-PHOSPHATASE 1B
GLYCOGEN-PHOSPHORYLASE
ALPHA-GLUCOSIDASE
ABSOLUTE-CONFIGURATION
STRUCTURE ELUCIDATION
DUAL INHIBITION
SEEDS
CONSTITUENT
DERIVATIVES
CHALCONE
Synthesis and preliminary evaluation of F-18-icotinib for EGFR-targeted PET imaging of lung cancer
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 3, 页码: 545—551
作者:
Lu, XM
;
Wang, C
;
Li, X
;
Gu, PL
;
Jia, LN
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/30
TYROSINE KINASE INHIBITOR
DERIVATIVES
BIOMARKERS
MUTATIONS
DRUG
Molecular Modeling Studies on Carbazole Carboxamide Based BTK Inhibitors Using Docking and Structure-Based 3D-QSAR
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 4
作者:
Li, Rui
;
Du, Yongli
;
Gao, Zhipei
;
Shen, Jingkang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
rheumatoid arthritis (RA)
Broton's tyrosine kinase (BTK)
carbazole carboxamide derivatives
3D-QSAR
comparative molecular field analysis (CoMFA)
comparative molecular similarity indices analysis (CoMSIA)
Synthesis and Activity Evaluation of Novel 3,4-Dihydro-benzo[b]-oxazepin-5(2H)-one Derivatives as Protein Kinases Inhibitors
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 6, 页码: 1463-1472
作者:
Hou Guige
;
Jiang Chengshi
;
Liu Hongchun
;
Tong Linjiang
;
Peng Xia
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
3,4-dihydro-benzo[b]oxazepin-5(2H)-one derivatives
synthesis
protein-tyrosine kinases inhibitors
ErbB1
ErbB2
Synthesis of Novel 3-aryl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene Derivatives and Their Biological Evaluation Against Protein Tyrosine Phosphatase 1B
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 5, 页码: 1161-1167
作者:
Wang, Wen-Long
;
Chen, Xia
;
Gao, Li-Xin
;
Sheng, Li
;
Li, Jing-Ya
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
3-aryl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene derivatives
inhibitors
one-pot synthesis
protein tyrosine phosphatase 1B
structure-activity relationships
DCLAK11, a multi-tyrosine kinase inhibitor, exhibits potent antitumor and antiangiogenic activity in vitro
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 10, 页码: 1266-1276
作者:
Guo, Xiao-bin
;
Zhu, Wei
;
Chen, Xian-jie
;
Tong, Lin-jiang
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
DCLAK11
substituted pyridin-3-amine derivatives
tyrosine kinase
EGFR
HER2
VEGFR2
anticancer
anti-angiogenesis
Discovery of Novel Tricyclic 5H-Pyridazino4,5-bindoles as Potent Antitumor Agents: Design, Synthesis and Biological Evaluation
期刊论文
OAI收割
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2015, 卷号: 31, 期号: 3, 页码: 372-380
作者:
Zhai Xin
;
Wang Limei
;
Shi Jiyue
;
Gong Ping
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/02/02
TYROSINE KINASE INHIBITORS
GROWTH-FACTOR RECEPTOR
ANALOGS
DERIVATIVES
BINDING
HARMINE
1-Anilino-5H-pyridazino4,5-bindole
EGFR inhibitor
Cytotoxicity
Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 8, 页码: 2827-2832
作者:
Shi, Dayong
;
Li, Jing
;
Jiang, Bo
;
Guo, Shuju
;
Su, Hua
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2013/09/24
Bromophenol derivatives
Protein tyrosine phosphatase 1B
Diarylmethane
Antidiabetic activities