中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海应用物理研究所 [5]
上海药物研究所 [3]
长春应用化学研究所 [2]
长春光学精密机械与物... [1]
化学研究所 [1]
西北高原生物研究所 [1]
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OAI收割 [15]
内容类型
期刊论文 [13]
CNKI期刊论文 [1]
会议论文 [1]
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2023 [1]
2020 [2]
2019 [1]
2018 [5]
2017 [1]
2016 [2]
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学科主题
分析化学与药物化学 [1]
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The new direction of drug development: Degradation of undruggable targets through targeting chimera technology
期刊论文
OAI收割
MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54
作者:
Liang, Xuewu
;
Ren, Hairu
;
Han, Fengyang
;
Liang, Renwen
;
Zhao, Jiayan
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2024/01/16
chimeric design
degradation System
PROTAC
targeted degradation technology
undruggable targets
Increasingly important role of numerical modeling in oceanic observation design strategy: A review
CNKI期刊论文
OAI收割
2020
作者:
Kun ZHANG
;
Mu MU
;
Qiang WANG
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/12/18
Observation design
Numerical modeling
Targeted observation
CNOP
A smart bioresponsive nanosystem with dual-modal imaging for drug visual loading and targeted delivery
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2020, 卷号: 391
作者:
Peng, Jingyi
;
Gong, Peiwei
;
Li, Shuohan
;
Kong, Fei
;
Ge, Xingxing
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/11/25
Structure design
FRET
Drug visual loading
Targeted delivery
Programming chain-growth copolymerization of DNA hairpin tiles for in-vitro hierarchical supramolecular organization
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2019, 卷号: 10, 期号: -, 页码: —
作者:
Zhang, HL
;
Wang, Y
;
Zhang, H
;
Liu, XG
;
Lee, A
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/12/30
TARGETED TRANSPORT
ACCURATE DESIGN
NANOTECHNOLOGY
NANOTUBES
POLYMERIZATION
NANOPARTICLES
HYDROGELS
DELIVERY
TUBE
Current Strategies and Applications for Precision Drug Design
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Wang, Chen
;
Xu, Pan
;
Zhang, Luyu
;
Huang, Jing
;
Zhu, Kongkai
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/01/08
precision medicine
precision drug design
computational modeling
deep learning
antibody-drug conjugates
ligand-targeted conjugates
Concept and Development of Framework Nucleic Acids
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 卷号: 140, 期号: 51, 页码: 17808-17819
作者:
Ge, ZL
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/17
DNA ORIGAMI NANOSTRUCTURES
TARGETED TRANSPORT
BUILDING-BLOCKS
FOLDING DNA
RNA
DESIGN
ARRAYS
GROWTH
NANOPARTICLES
COMPLEXES
Stimuli-Responsive DNA-Switchable Biointerfaces
期刊论文
OAI收割
LANGMUIR, 2018, 卷号: 34, 期号: 49, 页码: 15055-15068
作者:
Yin, FF
;
Mao, XH
;
Li, M
;
Zuo, XL
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/12/17
TARGETED TRANSPORT
NUCLEIC-ACIDS
NANOSTRUCTURES
NANOPARTICLES
NANOFLOWERS
MODULATION
PRINCIPLES
MOLECULES
DNAZYMES
DESIGN
Orally Administrated Small Molecule Drugs with Intestine Targeted Profile: Recent Development and Prospects
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2017, 卷号: 24, 期号: 35, 页码: 3921-3937
作者:
Cao, Hua
;
Wang, Kai
;
Ye, Yang-Liang
;
Shen, Jian-Hua
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Intestine targeted drugs
design strategies
lipophilicity
aqueous solubility
molecular weight
soft drugs
prodrugs
efflux transporters