中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [43]
化学研究所 [2]
大连化学物理研究所 [2]
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期刊论文 [56]
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Chemistry [2]
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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:
Dai,Manyun
;
Peng,Wan
;
Lin,Lisha
;
Wu,Zhanxuan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/07/17
Intestinal bleeding
Triptolide
Celastrol
Intestinal FXR
Tripterygium wilfordii
FARNESOID-X-RECEPTOR
BACTERIAL TRANSLOCATION
ACTIVATION
INFLAMMATION
DYSFUNCTION
TRIPTOLIDE
MICROBIOTA
PREVENTS
OBESITY
MICE
Triptolide analog LLDT-8 ameliorates psoriasis-like dermatitis in BALB/c mice via suppressing the IL-36 alpha signaling pathway
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Qi, Qing
;
Li, Qian
;
Zhu, Hongwen
;
Lu, Huimin
;
Yang, Xiaoqian
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/08/17
Triptolide
LLDT-8
Psoriasis
IL-36 alpha
IL-36 alpha pathway
Inflammation
Polyamine metabolism links gut microbiota and testicular dysfunction
期刊论文
OAI收割
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
作者:
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/04/02
Testicular dysfunction
Gut microbiota
Polyamine metabolism
Metabolomics
SMALL-MOLECULE INHIBITOR
ORNITHINE-DECARBOXYLASE
TRIPTOLIDE
SPERMINE
ACTIVATION
DISRUPTION
MECHANISMS
EXPRESSION
APOPTOSIS
TRANSPORT
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice
期刊论文
OAI收割
TOXICOLOGY LETTERS, 2020, 卷号: 333, 页码: 290-302
作者:
Zhao, Jie
;
Xie, Cen
;
Wang, Kanglong
;
Takahashi, Shogo
;
Krausz, Kristopher W.
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/12/21
Triptolide
Transcriptomics
Metabolomics
Apoptosis
Acylcarnitine
Injectable peptide hydrogel as intraperitoneal triptolide depot for the treatment of orthotopic hepatocellular carcinoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 5, 页码: 1050-1060
作者:
Zhao, Xiyue
;
Liu, Xiaoyu
;
Zhang, Pengcheng
;
Liu, Yiran
;
Ran, Wei
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
Self-assembly
Hydrogel
Peptide amphiphile
Triptolide
Hepatocellular carcinoma
Differential expression of the TwHMGS gene and its effect on triptolide biosynthesis in Tripterygium wilfordii
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 8, 页码: 575-584
作者:
Tong YuRu
;
Zhang YiFeng
;
Zhao YuJun
;
Hu TianYuan
;
Wang JiaDian
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/02/02
ENCODING 3-HYDROXY-3-METHYLGLUTARYL-COA SYNTHASE
HMG-COA SYNTHASE
METHYLERYTHRITOL PHOSPHATE
ISOPRENOID BIOSYNTHESIS
MOLECULAR-CLONING
CROSS-TALK
WILD-TYPE
PATHWAYS
OVEREXPRESSION
INTERMEDIATE
Overexpression
RNAi
HMGS
Triptolide
Acetyl-CoA
CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1386-1392
作者:
Xu, Ye
;
Zhang, Yi-fan
;
Chen, Xiao-yan
;
Zhong, Da-fang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
triptolide
(5R)-5-hydroxytriptolide
CYP3A4
ritonavir
dexamethasone
pharmacokinetics
immunosuppressant
traditional Chinese medicine
(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fc gamma receptor signaling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 1, 页码: 107-116
作者:
Qi, Qing
;
Li, Heng
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
triptolide
(5R)-5-hydroxytriptolide (LLDT-8)
prednisolone
glomerulonephritis
immune complexes
inflammation
Fc gamma receptor signaling
5r5hydroxytriptolideamelioratesantiglomerularbasementmembraneglomerulonephritisinnzwmicebyregulatingfcyreceptorsignaling
期刊论文
OAI收割
actapharmacologicasinica, 2018, 卷号: 39, 期号: 1, 页码: 107
作者:
Qi Qing
;
Li Heng
;
Lin Zemin
;
Yang Xiaoqian
;
Zhu Fenghua
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
triptolide
(5R)-5-hydroxytriptolide (LLDT-8)
prednisolone
glomerulonephritis
immune complexes
inflammation
Fcy receptor signaling
(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcy receptor signaling
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2018, 卷号: 39, 期号: 1, 页码: 107
作者:
Qi Qing
;
Li Heng
;
Lin Zemin
;
Yang Xiaoqian
;
Zhu Fenghua
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/24
triptolide
(5R)-5-hydroxytriptolide (LLDT-8)
prednisolone
glomerulonephritis
immune complexes
inflammation
Fcy receptor signaling