中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [23]
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期刊论文 [49]
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Targeting ST8SIA6-AS1 counteracts KRAS
G12C
inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:
Wang, Yafang
;
Yao, Mingyue
;
Li, Cheng
;
Yang, Kexin
;
Qin, Xiaolong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/01/26
KRAS(G12C)
c-Myc
PLK1
LncRNA
ST8SIA6-AS1
Drug resistance
Structure-based discovery of potent USP28 inhibitors derived from Vismodegib
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Zhou, Di
;
Xu, Zhuo
;
Huang, Yaodong
;
Wang, Hui
;
Zhu, Xiaoli
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
USP28
Structure-based
Vismodegib derivatives
Structure-activity relationships
c-Myc
Discovery of new small molecule inhibitors of the BPTF bromodomain
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 134, 页码: 106453
作者:
Liang, Xiaochen
;
Cao, Yu
;
Duan, Zhe
;
Wang, Mingchen
;
Zhang, Naixia
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/27
BPTF bromodomain
BPTF inhibitors
HTRF
c-Myc
BPTF inhibition antagonizes colorectal cancer progression by transcriptionally inactivating Cdc25A
期刊论文
OAI收割
REDOX BIOLOGY, 2022, 卷号: 55, 页码: 16
作者:
Guo, Ping
;
Zu, Shijia
;
Han, Shilong
;
Yu, Wendan
;
Xue, Guoqing
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/12/13
Colorectal cancer
BPTF
Cdc25A
c-Myc
Cell cycle
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
Carbon ion irradiation-induced DNA damage evokes cell cycle arrest and apoptosis via the pRb/E2F1/c-Myc signaling pathway in p53-deficient prostate cancer PC-3 cells
期刊论文
OAI收割
NUCLEAR SCIENCE AND TECHNIQUES, 2021, 卷号: 32, 期号: 3, 页码: 12
作者:
Wang, Fang
;
Xiao, Yi
;
Yan, Jun-Fang
;
Huang, Guo-Min
;
Zhang, Jin-Hua
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/12/10
Carbon ion irradiation
DNA damage
Cell cycle arrest
Apoptosis
C-Myc
Prostate cancer
NEK2 promotes proliferation, migration and tumor growth of gastric cancer cells via regulating KDM5B/H3K4me3
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2019, 卷号: 9, 期号: 11, 页码: 2364-2378
作者:
Li, Yiwei
;
Chen, Lijuan
;
Feng, Lixing
;
Zhu, Mengli
;
Shen, Qiang
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Gastric cancer
NEK2
KDM5B
beta-catenin
c-Myc
Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 页码: 156-175
作者:
Hu, Jianping
;
Wang, Yingqing
;
Li, Yanlian
;
Cao, Danyan
;
Xu, Lin
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
BRD4
BI2536
Indoline
WPF binders
c-Myc
PD-L1
Opposing roles of miR-294 and MBNL1/2 in shaping the gene regulatory network of embryonic stem cells
期刊论文
OAI收割
EMBO REPORTS, 2018, 卷号: 19, 期号: 6, 页码: -
作者:
Wu, Da-Ren
;
Gu, Kai-Li
;
Wang, Xi-Wen
;
Guo, Wen-Ting
;
Liao, Le-Qi
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2019/04/28
Rna-binding Proteins
Splicing Factors
Self-renewal
C-myc
Mechanisms
Promote
Differentiation
Pluripotency
Family
Expression