机构

• 上海药物研究所 [12]
• 高能物理研究所 [6]
• 金属研究所 [1]
• 大连化学物理研究所 [1]
• 水生生物研究所 [1]
• 上海应用物理研究所 [1]
• 更多

采集方式

• OAI收割 [22]
• iSwitch采集 [2]

内容类型

• 期刊论文 [24]

发表日期

• 2025 [1]
• 2024 [3]
• 2019 [2]
• 2018 [2]
• 2016 [3]
• 2015 [1]
• 更多

学科主题

• Biochemist... [1]
• Science & ... [1]
• 分析化学与药物化学 [1]

筛选

浏览/检索结果: 共24条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 PTM-centered therapy in malignant tumors: A new story of colchicine 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 4, 页码: 2295-2296 作者:  Huang, Min   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/08/20 Colchicine  SAE1  Post-translational modifications (PTM)-centered therapy  Malignant tumors   Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13 作者:  Zhai, Lin-hui;  Jia, Xing-long;  Chen, Yu-lu;  Liu, Mu-yin;  Zhang, Jing-dan   |  收藏  |  浏览/下载：95/0  |  提交时间：2024/12/25 colchicine  MLN4924  multi-omics analysis  phosphoproteomics  ubiquitinomics  kinase inhibitor   Target Identification and Mechanistic Characterization of Indole Terpenoid Mimics: Proper Spindle Microtubule Assembly Is Essential for Cdh1-Mediated Proteolysis of CENP-A 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 14 作者:     |  收藏  |  浏览/下载：51/0  |  提交时间：2024/07/12 Cdh1  CENP-A regulation  colchicine-binding site inhibitor  indole terpenoid  target identification   Colchicine-loaded transethosomes enhances transdermal permeability and therapeutic effects of acute gouty arthritis via vesicle extrusion and lipid perturbation 期刊论文  OAI收割 COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2024, 卷号: 687, 页码: 9 作者:  Zi, Miaomiao;  Ke, Jiming;  Jiang, Suping;  Cui, Xinge;  Zhang, Jing   |  收藏  |  浏览/下载：38/0  |  提交时间：2024/05/31 Transethosomes  Colchicine  Transdermal penetration mechanism  Acute gout   1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 448-456 作者:  Jiang, Junhang;  Zhang, Hao;  Wang, Chongqing;  Zhang, Qingsen;  Fang, Shaoyu   |  收藏  |  浏览/下载：48/0  |  提交时间：2020/07/01 Microtubule-targeting agents  Colchicine site inhibitors  Cis-trans photoisomerization  X-ray co-crystal structure  Water-soluble prodrug   The Structure of MT189-Tubulin Complex Provides Insights into Drug Design 期刊论文  OAI收割 LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 9, 页码: 1069-1073 作者:  Li, Zhongping;  Ma, Lingling;  Wu, Chengyong;  Meng, Tao;  Ma, Lanping   |  收藏  |  浏览/下载：50/0  |  提交时间：2020/07/01 Crystal structure  tubulin  colchicine binding site  inhibitor  MT189  drug design   Tc-99m-labeled dtpa-colchicine dimer with improved tumor uptake 期刊论文  iSwitch采集 Journal of labelled compounds & radiopharmaceuticals, 2018, 卷号: 61, 期号: 4, 页码: 395-401 作者:  Wang, Jianjun;  Ma, Junping;  Zhao, Qiuyu;  Yang, Wenjiang;  Xue, Jinquan 收藏  |  浏览/下载：60/0  |  提交时间：2019/04/23 Tc-99m  Dtpa-colchicine dimer  Label  Tumor uptake   Tc-99m-labeled DTPA-colchicine dimer with improved tumor uptake 期刊论文  OAI收割 JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2018, 卷号: 61, 期号: 4, 页码: 395-401 作者:  Zhao, QY;  Yang, WJ;  Zhang, YH;  Xue, JQ;  Liu, Y   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/09/24 Tc-99m  DTPA-colchicine dimer  label  tumor uptake   Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 112, 页码: 367-372 作者:  An, Weiteng;  Wang, Wei;  Yu, Ting;  Zhang, Yongliang;  Miao, Zehong   |  收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08 Anticancer agents  Tubulin inhibitor  Intra-molecular hydrogen bonding  Colchicine binding site   Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules 期刊论文  OAI收割 MOLECULAR PHARMACOLOGY, 2016, 卷号: 89, 期号: 2, 页码: 233—242 作者:  Wang, YX;  Benz, FW;  Wu, YP;  Wang, QS;  Chen, YF 收藏  |  浏览/下载：47/0  |  提交时间：2016/09/12 TUBULIN  CHEMOTHERAPY  COLCHICINE  AGENTS  LIGANDS