中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
大连化学物理研究所 [6]
上海药物研究所 [5]
昆明植物研究所 [1]
过程工程研究所 [1]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2023 [1]
2022 [1]
2021 [1]
2015 [1]
2013 [1]
2011 [1]
更多
学科主题
Biochemist... [1]
Biophysics [1]
物理化学 [1]
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浏览/检索结果:
共13条,第1-10条
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A Mushroom P450-Monooxygenase Enables Regioand Stereoselective Biocatalytic Synthesis of Epoxycyclohexenones
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 49
作者:
Yang,Yan-Long
;
Zhou,Man
;
Yang,Lin
;
Gressler,Markus
;
Rassbach,Johannes
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/07/10
Biocatalysis
Biosynthesis
Cytochrome P450
Epoxycyclohexenone
Natural Products
OPPOSITE FACIAL SPECIFICITY
NATURAL-PRODUCTS
STREPTOMYCES LL-C10037
BIOSYNTHESIS
EPOXYQUINONE
CYTOCHROME-P450
FERMENTATION
PANEPOXYDONE
EPOXIDATION
INHIBITION
Liquorice Extract and 18 beta-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 14
作者:
Wang, Zhangting
;
Ma, Jiang
;
Yao, Sheng
;
He, Yisheng
;
Miu, Kai-Kei
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15
18 beta-glycyrrhetinic acid
pyrrolizidine alkaloid
cytochrome P450
metabolic activation
competitive inhibition
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
期刊论文
OAI收割
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:
Shackleford, David M.
;
Chiu, Francis C. K.
;
Katneni, Kasiram
;
Blundell, Scott
;
McLaren, Jenna
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
OZ439 (artefenomel)
malaria
metabolite identification
cytochrome P450 metabolism
cytochrome P450 inhibition
time-dependent inhibition
Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice
期刊论文
OAI收割
toxicology in vitro, 2015, 卷号: 29, 期号: 7, 页码: 1569-1576
作者:
He, Wei
;
Wu, Jing-Jing
;
Ning, Jing
;
Hou, Jie
;
Xin, Hong
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2015/11/17
Licochalcone A (LCA)
Human liver microsomes (HLMs)
Cytochrome P450 enzymes (CYPs)
Inhibition
Herb-drug interactions (HDIs)
Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes
期刊论文
OAI收割
food and chemical toxicology, 2013, 卷号: 56, 页码: 392-397
作者:
Qi, Xiao-Yi
;
Liang, Si-Cheng
;
Ge, Guang-Bo
;
Liu, Yong
;
Dong, Pei-Pei
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2014/09/11
Sanguinarine
Human liver microsomes
Cytochrome P450 enzyme
Drug-drug interaction
Time-dependent inhibition
Identification of Cytochrome P450 (CYP) Isoforms involved in the Metabolism of Corynoline, and Assessment of its Herb-Drug Interactions
期刊论文
OAI收割
phytotherapy research, 2011, 卷号: 25, 期号: 2, 页码: 256-263
作者:
Fang, Zhong-Ze
;
Zhang, Yan-Yan
;
Ge, Guang-Bo
;
Liang, Si-Cheng
;
Sun, Dong-Xue
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2015/11/12
corynoline
cytochrome P450 (CYP)
drug-herb interaction
time-dependent inhibition (TDI)
Inhibitory Effects of Curcumenol on Human Liver Cytochrome P450 Enzymes
期刊论文
OAI收割
phytotherapy research, 2010, 卷号: 24, 期号: 8, 页码: 1213-1216
作者:
Sun, Dong-Xue
;
Fang, Zhong-Ze
;
Zhang, Yan-Yan
;
Cao, Yun-Feng
;
Yang, Ling
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2010/11/30
cytochrome P450 (CYP)
curcumenol
drug-drug interaction
human liver microsomes
inhibition
enzyme kinetics
Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction
期刊论文
OAI收割
british journal of clinical pharmacology, 2010, 卷号: 69, 期号: 2, 页码: 193-199
作者:
Fang, Zhong-Ze
;
Zhang, Yan-Yan
;
Ge, Guang-Bo
;
Huo, Hong
;
Liang, Si-Cheng
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2015/11/12
cytochrome P450 (CYP)
drug-drug interaction
noscapine
time-dependent inhibition
warfarin
Interactions between human cytochrome P450 enzymes and steroids: physiological and pharmacological implications
期刊论文
OAI收割
expert opinion on drug metabolism & toxicology, 2009, 卷号: 5, 期号: 6, 页码: 621-629
作者:
Zhang, Yan-Yan
;
Yang, Ling
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2015/11/12
cytochrome P450
drug interactions
ginsenosides
inhibition
metabolic stability
microsomes
steroid
traditional Chinese medicine
The metabolism of CYP2C9 and CYP2C19 for gliclazide by homology modeling and docking study
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 卷号: 44, 期号: 2, 页码: 854-861
作者:
Yao, Yuan
;
Han, Wei-Wei
;
Zhou, Yi-Han
;
Li, Ze-Sheng
;
Li, Qiang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Cytochrome P450 protein
Gliclazide
Molecular docking
Substrate inhibition