中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
上海营养与健康研究所 [2]
大连化学物理研究所 [1]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2024 [1]
2019 [2]
2018 [1]
2013 [2]
2012 [1]
学科主题
Endocrinol... [1]
Science & ... [1]
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Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
期刊论文
OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:
Bian, Yi-cong
;
Meng, Jian
;
Hu, Tao
;
Ma, Sheng
;
Huang, Chen-rong
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/05/22
HSK7653
long-acting dipeptidyl peptidase-4 inhibitor
mass balance
metabolism
pharmacokinetics
radiolabelled
Saxagliptin alters bile acid profiles and yields metabolic benefits in drug-naive overweight or obese type 2 diabetes patient
期刊论文
OAI收割
JOURNAL OF DIABETES, 2019, 页码: 11
作者:
Li, Wen
;
Liu, Ruixin
;
Li, Xuelin
;
Tao, Bei
;
Zhai, Nan
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2019/12/02
bile acids
dipeptidyl peptidase-4 inhibitor
obesity
saxagliptin
type 2 diabetes
Saxagliptin alters bile acid profiles and yields metabolic benefits in drug-naive overweight or obese type 2 diabetes patient
期刊论文
OAI收割
JOURNAL OF DIABETES, 2019, 卷号: 11, 期号: 12, 页码: 982-992
作者:
Li, Wen
;
Liu, Ruixin
;
Li, Xuelin
;
Tao, Bei
;
Zhai, Nan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/09
bile acids
dipeptidyl peptidase-4 inhibitor
obesity
saxagliptin
type 2 diabetes
Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y(1 )and P2Y(12) receptors
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2018, 卷号: 8, 期号: -, 页码: 8084
作者:
Liu, Xuyang
;
Wu, Yiran
;
Stevens, Raymond C.
;
Zhao, Suwen
;
Gao, Zhan-Guo
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/12/09
bile acids
dipeptidyl peptidase-4 inhibitor
obesity
saxagliptin
type 2 diabetes
Synthesis and biological evaluation of pyrrolidine-2-carbonitrile and 4-fluoropyrrolidine-2-carbonitrile derivatives as dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 23, 页码: 7418-7429
作者:
Wang, Jiang
;
Feng, Ying
;
Ji, Xun
;
Deng, Guanghui
;
Leng, Ying
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Pyrrolidine-2-carbonitrile
4-Fluoropyrrolidine-2-carbonitrile
Dipeptidyl peptidase-4 inhibitor
Oral glucose tolerance test
Type 2 diabetes
Design, Synthesis, Structure-Activity Relationships, and Docking Studies of 1-(gamma-1,2,3-Triazol Substituted Prolyl)-(S)-3,3-Difluoropyrrolidines as a Novel Series of Potent and Selective Dipeptidyl Peptidase-4 Inhibitors
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2013, 卷号: 81, 期号: 2, 页码: 198-207
作者:
Zhang, Lei
;
Su, Mingbo
;
Li, Jingya
;
Ji, Xun
;
Wang, Jiang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
dipeptidyl peptidase-4
inhibitor
molecular docking
triazole
type 2 diabetes
acuteandchronicadministrationofshr117887anovelandspecificdipeptidylpeptidase4inhibitorimprovesmetaboliccontrolindiabeticrodentmodels
期刊论文
OAI收割
actapharmacologicasinica, 2012, 卷号: 33, 期号: 8, 页码: 1013
作者:
Liu Xiao
;
Zhang Lina
;
Ying Feng
;
Zhang Lei
;
Qu Hui
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
GLUCAGON-LIKE PEPTIDE-1
IMPROVED GLUCOSE-TOLERANCE
DRUG-NAIVE PATIENTS
BETA-CELL FUNCTION
GLYCEMIC CONTROL
IV INHIBITOR
INSULIN-SECRETION
DOUBLE-BLIND
ZUCKER RATS
EFFICACY
SHR117887
vildagliptin (LAF237)
dipeptidyl peptidase-4 (DPP-4)
type 2 diabetes mellitus
glucagon-like peptide-1 (GLP-1)
insulin
beta-cells