中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [27]
心理研究所 [4]
昆明动物研究所 [3]
深圳先进技术研究院 [2]
新疆理化技术研究所 [1]
大连化学物理研究所 [1]
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OAI收割 [41]
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期刊论文 [40]
会议论文 [1]
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2023 [1]
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2019 [3]
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浏览/检索结果:
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Discovery of orally effective and safe GPR40 agonists by incorporating a chiral, rigid and polar sulfoxide into 8-position to the carboxylic acid
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115267
作者:
Chen, Cheng
;
Guo, Shi-Meng
;
Sun, Yuanjun
;
Li, He
;
Hu, Nan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
GPR40
Glucose-stimulated insulin secretion
Type 2 diabetes mellitus
Lipophilicity
Liver safety
Three-in-one pharmacophore
2-(phenylsulfinyl)acetic acid
The prevalence and clinical characteristics of diabetes mellitus in Chinese inpatients with chronic schizophrenia: a multicenter cross-sectional study
期刊论文
OAI收割
PEERJ, 2021, 卷号: 9, 页码: 12
作者:
Wang, Yanni
;
Zeng, Lingyun
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/01/07
Schizophrenia
Diabetes mellitus
Prevalence
China
Clinical characteristics
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation
期刊论文
OAI收割
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:
Yang, Liu
;
Lei, Xian-Tao
;
Huang, Qi
;
Wang, Ting
;
Sun, Hong-Bin
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/05/24
GPR120 agonist
Insulin secretion
Anti-inflammation
Insulin resistance
Type 2 diabetes mellitus
Plasma level of peroxiredoxin 3 in patients with polycystic ovarian syndrome
期刊论文
OAI收割
BMC ENDOCRINE DISORDERS, 2019, 卷号: 19, 页码: 6
作者:
Liu, Hou-Li
;
Li, Tian-Tian
;
Yu, Ai-Qun
;
Li, Jingmin
;
Li, Xiaoyan
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/04/15
Peroxiredoxin
Reactive oxygen species
Oxidative stress
Polycystic ovarian syndrome
Insulin resistance
Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:
Tian, Xiaoting
;
Liu, Fang
;
Li, Zhixiong
;
Lin, Yunfei
;
Liu, Huan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
berberine
timosaponin B2
diabetes
combination treatments
drug-drug interaction
metabolites
hepatic metabolism
intestinal absorption
The association of plasma peroxiredoxin 3 with insulin in pregnant women
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 508, 期号: 3, 页码: 805-810
作者:
Wang, Li
;
Hao, Jun-Mei
;
Yu, Ai-Qun
;
Li, Tian-Tian
;
Liu, Ran-Ran
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/03/01
Peroxiredoxin
Oxidative Stress
Gestational Diabetes Mellitus
Insulin Resistance
Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 22, 页码: 5780-5791
作者:
Guo, Bin
;
Guo, Shimeng
;
Huang, Jing
;
Li, Jingya
;
Li, Jia
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
GPR40 agonist
2,3-Dihydrobenzo[b][1,4]dioxine
Insulin secretion
Type 2 diabetes mellitus
Anti-diabetic Effect of Punica granatum Flower Polyphenols Extract in Type 2 Diabetic Rats: Activation of Akt/GSK-3 beta and Inhibition of IRE1 alpha-XBP1 Pathways
期刊论文
OAI收割
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:
Tang, Dan
;
Liu, Liu
;
Ajiakber, Dildar
;
Ye, Jianping
;
Xu, Jianjun
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/01/08
type 2 diabetes mellitus
Punica granatum L. flower
anti-diabetic herb
oral glucose tolerance test
endoplasmic reticulum stress
insulin resistance
Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 15, 页码: 2599-2604
作者:
Sheng, Ren
;
Yang, Liu
;
Zhang, Yanchun
;
Xing, Enming
;
Shi, Rui
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
GPR120
Agonist biphenyl derivatives
OGTT
Type 2 diabetes
Effect of Medium-chain Fatty Acid-sensing Receptor GPR84 on Glucose and Lipid Metabolism in Mice
期刊论文
OAI收割
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 45, 期号: 8, 页码: 853-864
作者:
Fang You-Chen
;
Zheng Yang
;
Zheng Qing
;
Li Jing
;
Xie Xin
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
GPR84
medium-chain fatty acid-sensing receptor
obesity
lipid metabolism
hypercholesterolemia