中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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Sorafenib resistance and therapeutic strategies in hepatocellular carcinoma
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2025, 卷号: 1880, 期号: 3, 页码: 17
作者:
Zhang, Weijing
;
Hong, Xuechuan
;
Xiao, Yuling
;
Wang, Hongbo
;
Zeng, Xiaodong
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/06/23
Hepatocellular carcinoma
Sorafenib
Drug resistance
Therapeutic strategy
Design, synthesis, and activity evaluation of indole derivatives as potential stabilizers for p53 Y220C
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 121, 页码: 9
作者:
Li, Linquan
;
Gu, Xi
;
Meng, Jingyi
;
Wen, Yiming
;
Yi, Jing
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/05/27
p53 Y220C
Synthesis
Structural modification
Drug design
Nanobody-based drug delivery systems for cancer therapy
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2025, 卷号: 381, 页码: 29
作者:
Liu, Lin
;
Tu, Bin
;
Sun, Yao
;
Liao, Lingling
;
Lu, Xiaoling
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/04/24
Nanobody
VHH
Cancer therapy
Targeted drug delivery systems
Nanobody modification
A Hybrid-Targeting Nanoparticle for Penetrable Delivery of Temozolomide to Enhance Glioblastoma Therapy
期刊论文
OAI收割
NANO LETTERS, 2025, 卷号: 25, 期号: 19, 页码: 7989-7997
作者:
Wang, Guanru
;
Guo, Hao
;
Wei, Mengxin
;
Wang, Ying
;
Jin, Zengcai
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
glioblastoma
chemotherapy
drug delivery
tumor-specific drugaccumulation
tumor-suppressiveeffects
Screening of botanical drugs reveals the potential anti-human adenovirus activity of berberine
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2025, 卷号: 237, 页码: 9
作者:
Cao, Junyuan
;
Zhang, Hao
;
Zhang, Jixiang
;
Wang, Jinlin
;
Li, Chen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/04/24
Human adenovirus
Antiviral drug
Berberine
High-throughput screening
Applications of innovative synthetic strategies in anticancer drug discovery: The driving force of new chemical reactions
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 119, 页码: 36
作者:
Wang, Han
;
Ma, Xiaolong
;
Sun, Longkang
;
Bi, Tongyu
;
Yang, Weibo
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2025/04/01
Synthetic methodologies
Medicinal chemistry
New chemical reactions
Anticancer drug discovery
Synthesis and Evaluation of Optical Properties, SHP2 Inhibitory Activity, and Cellular Imaging for Novel 2-Quinolone Derivatives
期刊论文
OAI收割
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2025, 页码: 10
作者:
Zhang, Chun
;
Yang, Yuting
;
Gao, Li-Xin
;
Gan, Suya
;
Li, Jia
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/05/27
Fluorescent inhibitors
SHP2
2-quinolone derivatives
optical properties
drug tracing
medical diagnosis
Current landscape of metal-organic framework-mediated nucleic acid delivery and therapeutics
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2025, 卷号: 672, 页码: 21
作者:
Feng, Shiwei
;
Li, Yan
;
Tan, Zheng
;
Shen, Shiyang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
Metal-organic frameworks
Nucleic acids
Nanocarrier
Drug delivery
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Wang, Ze-chen
;
Zeng, Yue
;
Sun, Jin-yuan
;
Chen, Xue-qin
;
Wu, Hao-chen
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery
Development of a bispecific antibody-drug conjugate targeting EpCAM and CLDN3 for the treatment of multiple solid tumors
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 16
作者:
Luo, Meiying
;
Wang, Xiaohuan
;
Yu, Guoji
;
Ji, Jing
;
Li, Long
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/04/07
EpCAM
CLDN3
Antibody-drug conjugate
Dxd
Solid tumor