中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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机构
上海药物研究所 [10]
长春应用化学研究所 [8]
上海应用物理研究所 [4]
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OAI收割 [28]
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期刊论文 [28]
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2024 [1]
2022 [3]
2021 [2]
2020 [1]
2019 [1]
2018 [3]
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浏览/检索结果:
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In silico off-target profiling for enhanced drug safety assessment
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 2927-2941
作者:
Liu, Jin
;
Gui, Yike
;
Rao, Jingxin
;
Sun, Jingjing
;
Wang, Gang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/08/22
Drug safety
Off-target prediction
Adverse drug reactions
Toxicity
Molecular representation
Artificial intelligence
Smart drug delivery systems for precise cancer therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4098-4121
作者:
Wang, Xiaoyou
;
Li, Chong
;
Wang, Yiguang
;
Chen, Huabing
;
Zhang, Xinxin
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/04/10
Pharmaceutics
Smart drug delivery system
Stimuli-responsive
Receptor-ligand-based delivery
Nano-drug delivery systems
Precise therapy
Toxicity
Cancer
9.4 T static magnetic field ameliorates imatinib mesylate-induced toxicity and depression in mice
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022
作者:
Tian, Xiaofei
;
Wang, Chentai
;
Yu, Biao
;
Fan, Yixiang
;
Zhang, Lei
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/12/22
Static magnetic fields (SMFs)
Imatinib mesylate
Gastrointestinal stromal tumor (GIST)
Drug toxicity
Depression
Editorial: Oxidative stress related to cellular metabolism in lung health and diseases
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 1015423
作者:
Arunachalam, Karuppusamy
;
Anand, Krishnan
;
Palanisamy, Subramanian
;
Anathy, Vikas
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/08/21
reactive oxygen species
oxidative stress
lung disease
respiratory illness
drug toxicity and therapy
OBSTRUCTIVE PULMONARY-DISEASE
PREVALENCE
ASTHMA
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
OAI收割
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
p Metabolite Identification in the Preclinical and Clinical Phase of Drug Development
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 11, 页码: 838-857
作者:
Wu, Yali
;
Pan, Lulu
;
Chen, Zhendong
;
Zheng, Yuandong
;
Diao, Xingxing
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/06/15
Metabolite identification
drug toxicity
drug exposure
covalent-binding drug
drug safety
natural medicines
Blood exposure to graphene oxide may cause anaphylactic death in non-human primates
期刊论文
OAI收割
NANO TODAY, 2020, 卷号: 35, 页码: -
作者:
Lin, YF
;
Zhang, Y
;
Li, J
;
Kong, HT
;
Yan, QL
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收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/09/06
IN-VIVO
CARBON NANOTUBES
CHALLENGES
DRUG
NANOPARTICLES
NANOSHEETS
TOXICITY
DELIVERY
PROMISES
BIOLOGY
Intestinal Transporter-Associated Drug Absorption and Toxicity
期刊论文
OAI收割
DRUG TRANSPORTERS IN DRUG DISPOSITION, EFFECTS AND TOXICITY, 2019, 卷号: 1141, 页码: 361-405
作者:
Xue, Yaru
;
Ma, Chenhui
;
Hanna, Imad
;
Pan, Guoyu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Intestinal transporter
Drug absorption
Bile acid transport
BDDCS
Drug-induced toxicity
Structural and thermodynamic stability of uranyl-deferiprone complexes and the removal efficacy of U(vi) at the cellular level
期刊论文
OAI收割
DALTON TRANSACTIONS, 2018, 卷号: 47, 期号: 26, 页码: 8764-8770
作者:
Wang, XM
;
Ji, GX
;
Shi, C
;
Juan, DW
;
Chen, LH
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/17
IRON-CHELATION THERAPY
HYDROXYPYRIDINONATE LIGANDS
DECORPORATION AGENTS
DRUG DEFERIPRONE
ORAL DEFERIPRONE
TOXICITY
URANIUM
MICE
CATECHOLATE
MECHANISM