机构

• 上海药物研究所 [11]
• 计算技术研究所 [2]
• 高能物理研究所 [2]
• 化学研究所 [1]
• 过程工程研究所 [1]
• 上海应用物理研究所 [1]
• 更多

采集方式

• OAI收割 [18]
• iSwitch采集 [1]

内容类型

• 期刊论文 [19]

发表日期

• 2022 [3]
• 2020 [1]
• 2019 [1]
• 2018 [1]
• 2017 [5]
• 2015 [1]
• 更多

学科主题

• Biochemist... [1]
• Biotechnol... [1]
• Mathematic... [1]

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 10 作者:  Hu, Hangchen;  Wang, Qian;  Su, Haixia;  Shao, Qiang   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/04/10 Allosteric Modulator  Cysteine 270  Drug Design  Papain-Like Protease  SARS-CoV-2   Shape-directed drug release and transport of erythrocyte-like nanodisks augment chemotherapy 期刊论文  OAI收割 JOURNAL OF CONTROLLED RELEASE, 2022, 卷号: 350, 页码: 886-897 作者:  Wang, Ning;  Li, Jingyi;  Wang, Jie;  Nie, Di;  Jiang, Xiaohe   |  收藏  |  浏览/下载：45/0  |  提交时间：2022/12/13 Erythrocyte -like nanoparticles  Shape effect  Drug release  Tumor penetration  Biological barriers   DeepBindBC: A practical deep learning method for identifying native-like protein-ligand complexes in virtual screening 期刊论文  OAI收割 METHODS, 2022, 卷号: 205, 页码: 247-262 作者:  Zhang, Haiping;  Zhang, Tingting;  Saravanan, Konda Mani;  Liao, Linbu;  Wu, Hao   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/07/12 Native like protein-ligand  Drug virtual screening  ResNet  Deep learning  Human pancreatic alpha amylase inhibitor   Deep Learning Based Drug Screening for Novel Coronavirus 2019-nCov 期刊论文  OAI收割 INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES, 2020, 页码: 9 作者:  Zhang, Haiping;  Saravanan, Konda Mani;  Yang, Yang;  Hossain, Md Tofazzal;  Li, Junxin   |  收藏  |  浏览/下载：47/0  |  提交时间：2020/12/10 Coronavirus  Deep learning  Drug screening  Homology modeling  3C-like protease   The immunostimulatory effects and pro-apoptotic activity of rhCNB against Lewis lung cancer is mediated by Toll-like receptor 4 期刊论文  OAI收割 CANCER MEDICINE, 2019, 卷号: 8, 期号: 9, 页码: 4441-4453 作者:  Yang, Jinju;  Zhang, Hongwei;  Zhu, Ziwei;  Gao, Yadan;  Xiang, Benqiong   |  收藏  |  浏览/下载：76/0  |  提交时间：2019/10/18 antitumor drug  antitumor immunity  innate immunity  rhCNB  Toll-like receptor 4   Nanoscale delivery systems for cancer immunotherapy 期刊论文  OAI收割 MATERIALS HORIZONS, 2018, 卷号: 5, 期号: 3, 页码: 344-362 作者:  Wang, ZJ;  Liu, WH;  Shi, JY;  Chen, N;  Fan, CH   |  收藏  |  浏览/下载：83/0  |  提交时间：2018/09/06 Car-t-cells  Antigen-presenting Cells  Tumor-infiltrating Lymphocytes  Membrane-coated Nanoparticles  Iron-oxide Nanoparticles  Enhanced Immune-response  Virus-like Particles  Drug-delivery  Photothermal Therapy  In-vivo   Cross-Dehydrogenative Coupling Reactions Applied in the Construction of Privileged Heterocycles 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 11, 页码: 2850-2858 作者:  Hu, Wei;  Long, Yaqiu   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 cross-dehydrogenative coupling  C-H functionalization  drug-like privileged scaffold   Near infrared light triggered nitric oxide releasing platform based on upconversion nanoparticles for synergistic therapy of cancer stem-like cells 期刊论文  iSwitch采集 Science bulletin, 2017, 卷号: 62, 期号: 14, 页码: 985-996 作者:  Zhang, Xiao;  Guo, Zhao;  Liu, Jing;  Tian, Gan;  Chen, Kui 收藏  |  浏览/下载：39/0  |  提交时间：2019/04/23 Upconversion nanoparticles  Nitric oxide  Cancer stem-like cells  Synergistic effect of no and chemotherapy  Drug resistance reversal   A pH-Responsive Yolk-Like Nanoplatform for Tumor Targeted Dual-Mode Magnetic Resonance Imaging and Chemotherapy 期刊论文  OAI收割 ACS NANO, 2017, 卷号: 11, 期号: 7, 页码: 7049-7059 作者:  Sun, Xiao;  Du, Ruohong;  Zhang, Li;  Zhang, Guilong;  Zheng, Xiaojia   |  收藏  |  浏览/下载：68/0  |  提交时间：2018/08/16 Yolk-like Fe3o4@gd2o3  Targeted  Dual-mode Mr Imaging Drug Delivery System  Cisplatin  Ph Responsive  Cancer Chemotherapy   Optimization and Synthesis of Pyridazinone Derivatives as Novel Inhibitors of Hepatitis B Virus by Inducing Genome-free Capsid Formation 期刊论文  OAI收割 ACS INFECTIOUS DISEASES, 2017, 卷号: 3, 期号: 3, 页码: 199-205 作者:  Lu, Dong;  Liu, Feifei;  Xing, Weiqiang;  Tong, Xiankun;  Wang, Lang   |  收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 pyridazinone  HBV DNA-free capsids  drug-like optimization  SAR study  lead candidate