中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
化学研究所 [3]
昆明植物研究所 [2]
长春应用化学研究所 [2]
南海海洋研究所 [1]
西北高原生物研究所 [1]
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OAI收割 [22]
内容类型
期刊论文 [22]
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2022 [3]
2020 [1]
2019 [3]
2018 [4]
2016 [2]
2015 [1]
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学科主题
Chemistry,... [1]
分析化学与药物化学 [1]
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Aberrant peribiliary gland niche exacerbates fibrosis in primary sclerosing cholangitis and a potential therapeutic strategy
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2022, 卷号: 153, 页码: 12
作者:
Wu, Shouyan
;
Cao, Yuhan
;
Lu, Henglei
;
Qi, Xinming
;
Sun, Jianhua
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/09/30
Primary sclerosing cholangitis (PSC)
Peribiliary gland niche
Ductular reaction
Fibrosis
Therapeutic strategy
18?-glycyrrhetinic acid (GA)
Nrf2-mediated liver protection by 18 beta-glycyrrhetinic acid against pyrrolizidine alkaloid-induced toxicity through PI3K/Akt/GSK3 beta pathway
期刊论文
OAI收割
PHYTOMEDICINE, 2022, 卷号: 102, 页码: 12
作者:
Wang, Zhangting
;
Ma, Jiang
;
He, Yisheng
;
Miu, Kai-Kei
;
Yao, Sheng
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2022/08/30
Pyrrolizidine alkaloids
Herb-induced liver injury
18 beta-glycyrrhetinic acid
Liquorice
Nuclear factor erythroid-2-related factor 2
PI3K/Akt/GSK3 beta
Liquorice Extract and 18 beta-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 14
作者:
Wang, Zhangting
;
Ma, Jiang
;
Yao, Sheng
;
He, Yisheng
;
Miu, Kai-Kei
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15
18 beta-glycyrrhetinic acid
pyrrolizidine alkaloid
cytochrome P450
metabolic activation
competitive inhibition
Research progress on the protective effects of licorice-derived 18 beta-glycyrrhetinic acid against liver injury
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Wu, Shou-yan
;
Wang, Wen-jie
;
Dou, Jin-hui
;
Gong, Li-kun
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
18 beta-glycyrrhetic acid
licorice preparation
liver injury
glycyrrhetinic acid target
Synthesis and structure-activity relationship studies of water-soluble beta-cyclodextrin-glycyrrhetinic acid conjugates as potential anti-influenza virus agents
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 328-338
作者:
Liang, Shuobin
;
Li, Man
;
Yu, Xiaojuan
;
Jin, Hongwei
;
Zhang, Yongmin
  |  
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2019/04/15
Glycyrrhetinic acid
Cyclodextrin
Click reaction
Influenza virus
Inhibitors
Efficient production of glycyrrhetinic acid in metabolically engineered Saccharomyces cerevisiae via an integrated strategy
期刊论文
OAI收割
MICROBIAL CELL FACTORIES, 2019, 卷号: 18
作者:
Wang, CX
;
Su, XY
;
Sun, MC
;
Zhang, MT
;
Wu, JJ
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2019/06/14
Glycyrrhetinic acid
BETA-AMYRIN SYNTHASE
Triterpene
HETEROLOGOUS PRODUCTION
Saccharomyces cerevisiae
BIOSYNTHETIC-PATHWAY
Metabolic engineering
CYTOCHROME-P450
LICORICE
GLYCYRRHIZIN
PROTOPANAXADIOL
OVERPRODUCTION
OPTIMIZATION
MILTIRADIENE
Mitochondria-targeted triphenylphosphonium conjugated glycyrrhetinic acid derivatives as potent anticancer drugs
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2019, 卷号: 85, 页码: 179, 190
作者:
Ji, Min
;
Wang, Hengshan
;
Jin, Le
;
Dai, Lumei
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/09/09
Glycyrrhetinic acid
Anti-tumor
Mitochondria
Apoptosis
18 beta-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-yan
;
Cui, Shi-chao
;
Wang, Le
;
Zhang, Yi-ying
;
Yan, Xiao-xia
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
hepatoprotective effect
cholestatic liver injury
18 beta-glycyrrhetinic acid (18b-GA)
FXR
Sirt1
bile acid transporters
18glycyrrhetinicacidprotectsagainstalphanaphthylisothiocyanateinducedcholestasisthroughactivationofthesirt1fxrsignalingpathway
期刊论文
OAI收割
中国药理学报英文版, 2018, 卷号: 039, 期号: 012, 页码: 1865
作者:
Shouyan Wu
;
Shichao Cui
;
Le Wang
;
Yiting Zhang
;
Xiaoxia Yan
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
hepatoprotective
effect
cholestatic
liver
injury
18β-glycyrrhetinic
acid
(18b-GA)
FXR
Sirt1
bile
acid
transporters
18β-Glycyrrhetinic acid protects against alphanaphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1865
作者:
Wu Shouyan
;
Cui Shichao
;
Wang Le
;
Zhang Yiting
;
Yan Xiaoxia
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/12/24
hepatoprotective effect
cholestatic liver injury
18β-glycyrrhetinic acid (18b-GA)
FXR
Sirt1
bile acid transporters