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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [24]
西北高原生物研究所 [1]
武汉病毒研究所 [1]
中国科学院大学 [1]
上海营养与健康研究所 [1]
昆明动物研究所 [1]
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期刊论文 [28]
会议论文 [1]
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2023 [2]
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Gastroente... [1]
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浏览/检索结果:
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Oral Delivery of Gemcitabine-Loaded Glycocholic Acid-Modified Micelles for Cancer Therapy
期刊论文
OAI收割
ACS NANO, 2023, 卷号: 17, 期号: 18, 页码: 18074-18088
作者:
Zang, Wenqing
;
Gao, Duo
;
Yu, Miaorong
;
Long, Manmei
;
Zhang, Zhuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
oral delivery
gemcitabine
micelles
glycocholic acid
chemotherapy
Saikosaponins regulate bile acid excretion in mice liver and ileum by activating farnesoid X receptor and bile acid transporter
期刊论文
OAI收割
PHYTOTHERAPY RESEARCH, 2023, 页码: 15
作者:
Wang, YuKun
;
Li, Jing
;
Wu, Li
;
Qin, XueMei
;
Xie, Cen
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
bile acids
enterohepatic circulation
FXR-related genes
saikosaponins
Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22
作者:
Xie, Ningjie
;
Wang, Hong
;
Qin, Hua
;
Guo, Zitao
;
Xue, Hao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
hepatic impairment
ezetimibe
active metabolites
phase II enzymes
transporters
first-pass metabolism
inhibitory bile acids
FEK self-assembled peptide hydrogels facilitate primary hepatocytes culture and pharmacokinetics screening
期刊论文
OAI收割
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2022, 页码: 13
作者:
He, Ting
;
Qiao, Shida
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/06/15
biliary excretion index
FEFEFKFK self-assembling peptide hydrogel
metabolic enzymes
rat primary hepatocytes
sandwich culture
transporters
Metabolic Activation of Retrorsine may Disrupt Bile Acid Homeostasis in Mice through the Nrf2 Pathway
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 11, 页码: 870-881
作者:
Pang, Xiaoyan
;
Tang, Chongzhuang
;
Cao, Peng
;
Zhou, Lei
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/06/15
Retrorsine
bile acid
oxidative stress
reactive metabolite
transporter
Nrf2
HgS and Zuotai differ from HgCl2 and methyl mercury in intestinal Hg absorption, transporter expression and gut microbiome in mice
期刊论文
OAI收割
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 379
作者:
Zhang, Bin-Bin
;
Liu, Yong-Mei
;
Hu, An-Ling
;
Xu, Shang-Fu
;
Fan, Li-Da
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/11/26
HgS
Zuotai
HgCl2
MeHg
Gut microbiome
Gut transporter
Intestinal Transporter-Associated Drug Absorption and Toxicity
期刊论文
OAI收割
DRUG TRANSPORTERS IN DRUG DISPOSITION, EFFECTS AND TOXICITY, 2019, 卷号: 1141, 页码: 361-405
作者:
Xue, Yaru
;
Ma, Chenhui
;
Hanna, Imad
;
Pan, Guoyu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Intestinal transporter
Drug absorption
Bile acid transport
BDDCS
Drug-induced toxicity
Trimethylamine N-oxide attenuates high-fat high-cholesterol diet-induced steatohepatitis by reducing hepatic cholesterol overload in rats
期刊论文
OAI收割
WORLD JOURNAL OF GASTROENTEROLOGY, 2019, 卷号: 25, 期号: 20, 页码: 2450-2462
作者:
Zhao, Ze-Hua
;
Xin, Feng-Zhi
;
Zhou, Da
;
Liu, Xiao-Lin
;
Yang, Rui-Xu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/09
Gut microbiota
Trimethylamine N-oxide
Nonalcoholic steatohepatitis
Endoplasmic reticulum stress
Cholesterol
18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
OAI收割
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-Yan
;
Cui, Shi-Chao
  |  
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2019/01/08
18 beta-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-yan
;
Cui, Shi-chao
;
Wang, Le
;
Zhang, Yi-ying
;
Yan, Xiao-xia
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
hepatoprotective effect
cholestatic liver injury
18 beta-glycyrrhetinic acid (18b-GA)
FXR
Sirt1
bile acid transporters