机构

• 上海药物研究所 [9]
• 上海生物化学与细胞生... [4]
• 金属研究所 [2]
• 上海营养与健康研究所 [2]
• 水生生物研究所 [1]
• 中国科学院大学 [1]
• 更多

采集方式

• OAI收割 [19]
• iSwitch采集 [1]

内容类型

• 期刊论文 [20]

发表日期

• 2020 [2]
• 2019 [3]
• 2018 [3]
• 2017 [3]
• 2015 [2]
• 2013 [3]
• 更多

学科主题

• Science & ... [2]
• Biochemist... [1]
• Cell Biolo... [1]
• Chemistry [1]
• Materials ... [1]

筛选

浏览/检索结果: 共20条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10 作者:  Min, Wenjian;  Hou, Zeng;  Zhang, Fang;  Xie, Shengnan;  Yuan, Kai   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 Histone methylation  Lysine methyltransferase  SET7  Small-molecule inhibitor  Virtual screening   The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein-Protein Interaction 期刊论文  OAI收割 CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 33, 页码: 5530-5542 作者:  Ye, Xiaoqing;  Chen, Gang;  Jin, Jia;  Zhang, Binzhong;  Wang, Yinda   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/12/24 WDR5  MLL1  histone methyltransferase  small-molecular inhibitor  epigenetics  human acute leukemia   C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1457-1465 作者:  Shi, Yi;  Ma, Hong-lei;  Zhuang, You-wen;  Wang, Xiao-xi;  Jiang, Yi   |  收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 PRC2  C10ORF12  H3K27me3  histone methyltransferase  epigenetic regulation  histone modification   SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells Through Mediating the Transcriptional Activation of Key Mesendodermal Genes 期刊论文  OAI收割 STEM CELLS, 2019, 卷号: 37, 期号: 11, 页码: 1401-1415 作者:  Bai, Hua-Jun;  Zhang, Peng;  Liang, He;  Yang, Huang-Tian;  Ma, Li   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/12/09 Human embryonic stem cells  SET and MYND domain-containing protein 2  Histone methyltransferase  Mesendodermal differentiation  Brachyury  Eomesodermin  Mix paired-like homeobox  Goosecoid homeobox   c10orf12modulatesprc2histonemethyltransferaseactivityandh3k27me3levels 期刊论文  OAI收割 actapharmacologicasinica, 2019, 卷号: 40, 期号: 11, 页码: 1457 作者:  Shi Yi;  Ma Honglei;  Zhuang Youwen;  Wang Xiaoxi;  Jiang Yi   |  收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01 REPRESSIVE COMPLEX 2  GENOMIC TARGETS  POLYCOMB  PROTEIN  CHROMATIN  RECRUITMENT  JARID2  DIFFERENTIATION  BINDING  METHYLATION  PRC2  C10ORF12  H3K27me3  histone methyltransferase  epigenetic regulation  histone modification   Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2018, 卷号: 80, 页码: 649-654 作者:     |  收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08 Pyrimidylaminoquinoline  Nonnucleoside DOT1L inhibitors  Amino side chains  Mixed-linage leukemia  Histone lysine methyltransferase   Architecture and subunit arrangement of the complete Saccharomyces cerevisiae COMPASS complex 期刊论文  OAI收割 SCIENTIFIC REPORTS, 2018, 卷号: 8, 期号: 1, 页码: 17405 作者:  Wang, Yanxing;  Ding, Zhanyu;  Liu, Xiangyang;  Bao, Yu;  Huang, Min   |  收藏  |  浏览/下载：77/0  |  提交时间：2019/04/28 Histone H3k4 Methylases  Set Domain  Methyltransferase Complex  Structural Basis  Lysine 4  Protein  Family  Ubiquitination  Termination  Recruits   PRDM4 mediates YAP-induced cell invasion by activating leukocyte-specific integrin beta 2 expression 期刊论文  OAI收割 EMBO REPORTS, 2018, 卷号: 19, 期号: 6, 页码: - 作者:  Liu, Huan;  Dai, Xiaoming;  Cao, Xiaolei;  Yan, Huan;  Ji, Xinyan   |  收藏  |  浏览/下载：59/0  |  提交时间：2019/04/28 Yes-associated Protein  Histone Methyltransferase Complex  Hippo Signaling Pathway  Organ Size Control  Transcription Factor  Prostate-cancer  Tissue Homeostasis  Gene-expression  Growth-control  Myeloid Cells   Structure of the PRC2 complex and application to drug discovery 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 963-976 作者:  Shi, Yi;  Wang, Xiao-xi;  Zhuang, You-wen;  Jiang, Yi;  Melcher, Karsten   |  收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 PRC2  histone methyltransferase  H3K27me3  nucleosome  structure  drug discovery   structureoftheprc2complexandapplicationtodrugdiscovery 期刊论文  OAI收割 actapharmacologicasinica, 2017, 卷号: 38, 期号: 7, 页码: 963 作者:  Shi Yi;  Wang Xiaoxi;  Zhuang Youwen;  Jiang Yi;  Melcher Karsten   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 PRC2  histone methyltransferase  H3K27me3  nucleosome  structure  drug discovery