中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
大连化学物理研究所 [1]
采集方式
OAI收割 [11]
内容类型
期刊论文 [11]
发表日期
2023 [1]
2022 [1]
2021 [1]
2020 [2]
2017 [1]
2016 [1]
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化学干预N~6-甲基腺嘌呤修饰的研究进展
期刊论文
OAI收割
高等学校化学学报, 2023, 卷号: 44, 期号: 3
作者:
郇歆宇
;
赖淦强
;
黄悦
;
杨财广
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/07/18
N~6-Methyladenosine modification
Methyltransferase
Demethylase
Small molecule inhibitor
Small molecule agonist
N~6-甲基腺嘌呤修饰
甲基转移酶
去甲基化酶
小分子抑制剂
小分子激动剂
Inhibition of protein arginine methyltransferase 1 alleviates liver fibrosis by attenuating the activation of hepatic stellate cells in mice
期刊论文
OAI收割
FASEB JOURNAL, 2022, 卷号: 36, 期号: 9, 页码: 14
作者:
Yan, Fang-Zhi
;
Qian, Hui
;
Liu, Fang
;
Ding, Chen-Hong
;
Liu, Shu-Qing
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/09/30
hepatic stellate cell
inflammation
inhibitor
liver fibrosis
protein arginine methyltransferase 1
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10
作者:
Min, Wenjian
;
Hou, Zeng
;
Zhang, Fang
;
Xie, Shengnan
;
Yuan, Kai
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Histone methylation
Lysine methyltransferase
SET7
Small-molecule inhibitor
Virtual screening
The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein-Protein Interaction
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 33, 页码: 5530-5542
作者:
Ye, Xiaoqing
;
Chen, Gang
;
Jin, Jia
;
Zhang, Binzhong
;
Wang, Yinda
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
WDR5
MLL1
histone methyltransferase
small-molecular inhibitor
epigenetics
human acute leukemia
Cycloalkane analogues of sinefungin as EHMT1/2 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4579-4594
作者:
Liu, Qing
;
Cai, Xiaoqing
;
Yang, Dehua
;
Chen, Yi
;
Wang, Yafang
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Methyltransferase inhibitor
Cycloalkyl substituted analogue
Natural product
Sinefungin
Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 122, 页码: 382-393
作者:
Kondengaden, Shukkoor M.
;
Luo, Liu-fei
;
Huang, Kenneth
;
Zhu, Mengyuan
;
Zang, Lanlan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Lysine methyltransferase
G9a inhibitor
Leukemia
MALDI-TOF assay
Interaction Between DNA/histone Methyltransferases and their Inhibitors
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2015, 卷号: 22, 期号: 3, 页码: 360-372
作者:
Hu, J.
;
Chen, S.
;
Kong, X.
;
Zhu, K.
;
Cheng, S.
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
DNA methyltransferase
drug discovery
epigenetic therapy
histone methyltransferase
inhibitor
EZH2: biology, disease, and structure-based drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 2, 页码: 161-174
作者:
Tan, Jin-zhi
;
Yan, Yan
;
Wang, Xiao-xi
;
Jiang, Yi
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
EZH2
PRC2
transcriptional repression
gene activation
anticancer drug
crystal structure
SET domain
methyltransferase inhibitor
epigenetic therapy
ezh2biologydiseaseandstructurebaseddrugdiscovery
期刊论文
OAI收割
actapharmacologicasinica, 2014, 卷号: 35, 期号: 2, 页码: 161
作者:
Tan Jinzhi
;
Yan Yan
;
Wang Xiaoxi
;
Jiang Yi
;
Xu H Eric
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
EZH2
PRC2
transcriptional repression
gene activation
anticancer drug
crystal structure
SET domain
methyltransferase inhibitor
epigenetic therapy