中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
海洋研究所 [3]
上海生物化学与细胞生... [3]
合肥物质科学研究院 [3]
昆明植物研究所 [2]
生态环境研究中心 [2]
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采集方式
OAI收割 [28]
内容类型
期刊论文 [28]
发表日期
2024 [5]
2023 [1]
2022 [5]
2021 [2]
2020 [1]
2019 [1]
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学科主题
Biochemist... [1]
Biochemist... [1]
Cell Biolo... [1]
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Oncology; ... [1]
Pharmacolo... [1]
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浏览/检索结果:
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The Evolution and Biological Activity of Metazoan Mixed Lineage Kinase Domain-Like Protein (MLKL)
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 卷号: 25, 期号: 19, 页码: 12
作者:
Wang, Qingyue
;
Yuan, Zihao
;
Xu, Hang
;
Chen, Yuan
;
Sun, Li
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/12/20
MLKL
necroptosis
evolution
Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 21
作者:
Lan, Yaohan
;
Ji, Yinchun
;
Peng, Xia
;
Duan, Wenhu
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/08/22
autoimmune disease
necroptosis inhibitor
pharmacokinetic profile
receptor interacting protein kinase 1 (RIPK1)
structural optimization
Editorial: Programmed cell death in aquatic animals
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 2
作者:
Wang, Qingchao
;
Yang, Dahai
;
Zhang, Linlin
;
Powell, Madison
;
Lin, Yu-Hung
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/09/02
programmed cell death
apoptosis
necroptosis
FAS/FASL
MLKL
Paralichthys olivaceus
MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11
作者:
Hao, Kangwei
;
Xu, Hang
;
Jiang, Shuai
;
Sun, Li
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/04/07
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1219362
作者:
Guo,Xiuping
;
Li,Rui
;
Cui,Jinjin
;
Hu,Chujuan
;
Yu,Haoyang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/09
Erigeron breviscapus injection
Dengzhanxixin
Erigeron breviscapus (Vant
) Hand
-Mazz
colorectal cancer
necroptosis
drug resistance
TUMOR-NECROSIS-FACTOR
COLORECTAL-CANCER
NATURAL COMPOUNDS
SCUTELLARIN
APOPTOSIS
PROLIFERATION
MACROPHAGES
MIGRATION
INVASION
THERAPY
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Wang, Zuo-wei
;
Zou, Feng-ming
;
Wang, Ao-li
;
Yang, Jing
;
Jin, Rui
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/12/22
AZD4547
RIPK1
inhibitors
SIRS model
anti-necroptosis
The pathogenesis of organ fibrosis: Focus on necroptosis
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2022
作者:
Hao, Min
;
Han, Xin
;
Yao, Zhouhui
;
Zhang, Han
;
Zhao, Mengting
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/12/22
liver fibrosis
lung fibrosis
MLKL
necroptosis
RIPK1
3
tissue fibrosis
Alteration of intestinal microecology by oral antibiotics promotes oral squamous cell carcinoma development
期刊论文
OAI收割
MOLECULAR IMMUNOLOGY, 2022, 卷号: 149, 期号: 0, 页码: 94-106
作者:
Wei, Wei
;
Li, Jia
;
Liu, Fan
;
Wu, Miaomiao
;
Xiong, Kaixin
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/11/09
CANCER
TYROSINE
METABOLISM
OPPORTUNITIES
NECROPTOSIS
MICROBIOME
DISEASE
VACCINE
HEAD
Necrosulfonamide Selectively Induces DNA Double-Strand Breaks in Acute Myeloid Leukemia Cells
期刊论文
OAI收割
CHEMICAL RESEARCH IN TOXICOLOGY, 2022, 卷号: 35, 期号: 3, 页码: 387-391
作者:
Chen, Shaokun
;
Lai, Weiyi
;
Li, Xiangjun
;
Wang, Hailin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/11/08
MIXED LINEAGE KINASE
INHIBITION
APOPTOSIS
PROTEIN
REPAIR
NECROPTOSIS
CANCER
DAMAGE
DEATH