机构

• 上海药物研究所 [7]
• 新疆理化技术研究所 [1]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2021 [3]
• 2016 [1]
• 2014 [2]
• 2011 [1]
• 2008 [1]

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides 期刊论文  OAI收割 CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12 作者:  Xue, Haitao;  Guo, Shuang;  Hu, Tianwen;  Wei, Daibao;  Xie, Yuanchao   |  收藏  |  浏览/下载：55/0  |  提交时间：2022/01/18 2 '-deoxy carbocyclic nucleoside  antiviral activity  hepatitis B virus  Mitsunobu reaction   Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and beta-d-N-4-hydroxycytidine 期刊论文  OAI收割 VIROLOGICA SINICA, 2021, 页码: 9 作者:  Xie, Yuanchao;  Guo, Xiaozhen;  Hu, Tianwen;  Wei, Daibao;  Ma, Xiuli   |  收藏  |  浏览/下载：45/0  |  提交时间：2021/05/24 Porcine epidemic diarrhea virus (PEDV)  Nucleoside analog  RNA dependent RNA polymerase (RdRp)  Antiviral activity   Potency and pharmacokinetics of GS-441524 derivatives against SARS-CoV-2 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 46, 期号: 9, 页码: 1-12 作者:  Wei, DB (Wei, Daibao);  Hu, TW (Hu, Tianwen);  Zhang, YM (Zhang, Yumin);  Zheng, W (Zheng, Wei);  Xue, HT (Xue, Haitao)   |  收藏  |  浏览/下载：97/0  |  提交时间：2021/10/14 Covid-19  SARS-CoV-2  GS-441524  Antiviral  Nucleoside  Prodrug  Isobutyrate   Structure-based optimization and derivatization of 2-substituted quinolone-based non-nucleoside HCV NS5B inhibitors with submicromolar cellular replicon potency 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 12, 页码: 2900-2906 作者:  Cheng, Yu;  Shen, Jian;  Peng, Run-Ze;  Wang, Gui-Feng;  Zuo, Jian-Ping   |  收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 HCV NS5B polymerase  2-Alkyl quinolone  1,6-Naphthyridine-4,5-dione  Non-nucleoside inhibitor  Direct acting antiviral  Allosteric site   2-Aryl-3-carbonylquinolones: Design, Synthesis and Biological Evaluation of Novel HCV NS5B Polymerase Inhibitors 期刊论文  OAI收割 ACTA CHIMICA SINICA, 2014, 卷号: 72, 期号: 8, 页码: 906-913 作者:  Wang Shenfeng;  Lin Jianping;  He Peilan;  Zuo Jianping;  Long Yaqiu   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 HCV NS5B polymerase  2-substituted quinolone-3-carboxylic acid  non-nucleoside inhibitor  direct acting antiviral  allosteric site   2芳基3羰基喹诺酮新型hcvns5b多聚酶抑制剂的设计合成和活性评估 期刊论文  OAI收割 化学学报, 2014, 卷号: 72, 期号: 8, 页码: 906 作者:  王沈丰;  林建平;  何佩岚;  左建平;  龙亚秋   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 HEPATITIS-C VIRUS  HIV-1 INTEGRASE INHIBITORS  INFECTION  NUCLEOTIDE  SCAFFOLD  SOFOSBUVIR  DISCOVERY  LEDGF/P75  ACIDS  HCV NS5B polymerase  2-substituted quinolone-3-carboxylic acid  non-nucleoside inhibitor  direct acting antiviral  allosteric site   Determination of lamivudine in human plasma by hydrophilic interaction chromatography(HILIC)tandem mass spectrometry 期刊论文  OAI收割 Chinese Journal of Pharmaceutical Analysis, 2011, 卷号: 31, 期号: 8, 页码: 1448-1452 作者:  SHI Rongwei;  LIU Ke;  CHEN Xiaoyan;  ZHANG Yifan;  ZHONG Dafang   |  收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 nucleoside antiviral  lamivudine  HPLC  mass spectrometry(MS)  plasma concentration   Rational design and synthesis of 2,2-bisheterocycle tandem derivatives as non-nucleoside hepatitis B virus inhibitors 期刊论文  OAI收割 CHEMMEDCHEM, 2008, 卷号: 3, 期号: 9, 页码: 1316-1321 作者:  Chen, Hai-Jun;  Wang, Wen-Long;  Wang, Gui-Feng;  Shi, Li-Ping;  Gu, Min   |  收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 antiviral agents  leucamide A  2,2-bisheterocycle tandem  hepatitis B virus  non-nucleoside inhibitors