中国科学院机构知识库网格
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Synergistic induction of immunogenic cell death and tumor microenvironment remodeling by biotinylated marine polysaccharide nanoparticles for enhanced colorectal cancer therapy
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2026, 卷号: 381, 页码: 20
作者:
Wang, Hui
;
Yu, Haoyu
;
Yang, Yan
;
Fu, Mengying
;
Geng, Lihua
  |  
收藏
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浏览/下载:0/0
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提交时间:2026/06/02
Chitosan
Fucoidan
Polysaccharide nanoparticles
Dual-targeting
Tumor microenvironment
Recent Advances in On-Tissue Chemical Derivatization Strategies for Enhancing MALDI-MSI
期刊论文
OAI收割
MASS SPECTROMETRY REVIEWS, 2025, 页码: 24
作者:
Huang, Meng
;
Qi, Xiaoyu
;
Zhu, Dafu
;
Zhou, Hao
;
Yuan, Jie
  |  
收藏
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浏览/下载:0/0
  |  
提交时间:2026/01/29
functional group targeting
ionization enhancement
MALDI mass spectrometry imaging
on-tissue chemical derivatization
spatial metabolomics
Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction-Associated Steatotic Liver Disease via a Galactose-Modified Supramolecular Near-Infrared Fluorescent Glycoprobe
期刊论文
OAI收割
ADVANCED FUNCTIONAL MATERIALS, 2025, 页码: 13
作者:
Wang, Han-Min
;
Dong, Lei
;
Hao, Qiu-Lian
;
Sun, Lu-Lu
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收藏
  |  
浏览/下载:0/0
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提交时间:2025/12/04
fluorescent glycoprobe
lipid droplets
liver targeting
metabolic dysfunction-associated steatotic liver disease (MASLD)
near-infrared
De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
;
Shan, Yiming
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收藏
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浏览/下载:30/0
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提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
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收藏
  |  
浏览/下载:49/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
A Mitochondrion-Targeted NIR-II Modulator for Synergistic Ferroptosis-Immunotherapy
期刊论文
OAI收割
SMALL, 2025, 页码: 13
作者:
Wang, Miao
;
Ding, Qihang
;
Su, Wuyue
;
Luo, Min
;
Yang, Runping
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收藏
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浏览/下载:36/0
  |  
提交时间:2025/06/23
antitumor immunity activity
ferroptosis
immunogenic cell death
mitochondria targeting
NIR-II modulator
Supramolecular cyclodextrin-based reservoir as nasal delivery vehicle for rivastigmine to brain
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2025, 卷号: 348, 页码: 14
作者:
Wang, Manli
;
Lv, Yuting
;
Xu, Huipeng
;
Zhao, Xiangyu
;
Zhang, Guoqing
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收藏
  |  
浏览/下载:59/0
  |  
提交时间:2024/12/11
Supramolecular reservoir
Intranasal administration
Rivastigmine
Cyclodextrin metal-organic framework
Borneol
Brain targeting
Advance on the effects of algal carotenoids on inflammatory signaling pathways
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 13
作者:
Wang, Yudi
;
Geng, Xinrong
;
Qin, Song
;
Che, Tuanjie
;
Yan, Libo
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收藏
  |  
浏览/下载:49/0
  |  
提交时间:2025/01/10
Algal carotenoids
Inflammatory signaling pathways
Targeting effect
Liver-targeted degradation of BRD4 reverses hepatic fibrosis and enhances metabolism in murine models
期刊论文
OAI收割
THERANOSTICS, 2025, 卷号: 15, 期号: 15, 页码: 7270-7290
作者:
Yuan, Shengjie
;
Nisar, Ayesha
;
Chen, Chuanjie
;
Dong, Xin
;
Pan, Yongzhang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/12/04
asialoglycoprotein receptor
BRD4 degradation
liver fibrosis
liver-targeting chimera
proteolysis-targeting chimera
Enhanced Gut-to-Liver Oral Drug Delivery via Ligand-Modified Nanoparticles by Attenuating Protein Corona Adsorption
期刊论文
OAI收割
ACS NANO, 2024, 卷号: 18, 期号: 52, 页码: 35310-35324
作者:
Wang, Jie
;
Zhang, Zilong
;
Zhang, Zhuan
;
Zou, Zhiwen
;
Zhuo, Yan
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2025/02/28
protein corona
ligand-modified nanoparticles
oral delivery
liver targeting
mucus