机构

• 上海药物研究所 [6]
• 昆明植物研究所 [1]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2019 [2]
• 2016 [1]
• 2015 [1]
• 2012 [2]
• 2006 [1]

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文  OAI收割 MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10 作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li   |  收藏  |  浏览/下载：81/0  |  提交时间：2019/07/29 aspidosperma-type  monoterpenoid indole alkaloids  antiproliferative activity  tubulin inhibitor  Bousigonia mekongensis   The Structure of MT189-Tubulin Complex Provides Insights into Drug Design 期刊论文  OAI收割 LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 9, 页码: 1069-1073 作者:  Li, Zhongping;  Ma, Lingling;  Wu, Chengyong;  Meng, Tao;  Ma, Lanping   |  收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01 Crystal structure  tubulin  colchicine binding site  inhibitor  MT189  drug design   Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 112, 页码: 367-372 作者:  An, Weiteng;  Wang, Wei;  Yu, Ting;  Zhang, Yongliang;  Miao, Zehong   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Anticancer agents  Tubulin inhibitor  Intra-molecular hydrogen bonding  Colchicine binding site   Design, synthesis and biological evaluation of colchicine derivatives as novel tubulin and histone deacetylase dual inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 95, 页码: 127-135 作者:  Zhang, Xuan;  Kong, Yannan;  Zhang, Jie;  Su, Mingbo;  Zhou, Yubo   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Colchicine  Dual inhibitor  HDAC  Tubulin  Hybrid   Synthesis and structure-activity relationship studies of cytotoxic vinorelbine amide analogues 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 24, 页码: 7547-7550 作者:  Hu, Lingjun;  Song, Weibin;  Meng, Yuhui;  Guo, Dean;  Liu, Xuan   |  收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 Vinorelbine  C-22 amide analogues  Tubulin inhibitor  Structure-activity relationship (SAR)  Cytotoxicity   Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G_2-M arrest and apoptosis in HeLa cells 期刊论文  OAI收割 Acta Pharmacologica Sinica, 2012, 卷号: 33, 期号: 3, 页码: 407 作者:  Ma Yiming;  Zhou Yubo;  Xie Chuanming;  Chen Dongmei;  Li Jia   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 ACTIVATED PROTEIN-KINASE  TUBULIN-BINDING AGENT  IN-VIVO  ANTIMICROBIAL ACTIVITY  ANTICANCER ACTIVITY  CYCLE ARREST  CANCER-CELLS  DERIVATIVES  INHIBITOR  RESISTANT  anticancer drug  6-chloro-4-(methoxyphenyl) coumarin  cell cycle arrest  microtubule depolymerization  apoptosis   4 '-Alkoxyl substitution enhancing the anti-mitotic effect of 5-(3 ',4 ',5 '-substituted)anilino-4-hydroxy-8-nitroquinazolines as a novel class of anti-microtubule agents 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 卷号: 16, 期号: 22, 页码: 5864-5869 作者:  Jin, Yi;  Zhou, Zu-Yu;  Tian, Wei;  Yu, Qiang;  Long, Ya-Qiu   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 quinazoline  mitosis inhibitor  tubulin polymerization  anti-microtubule agent  alkoxyl substitution  aniline  antiproliferative effect  cell cycle  tumor cells