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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [729]
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OAI收割 [729]
内容类型
期刊论文 [729]
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2024 [24]
2023 [67]
2022 [66]
2021 [58]
2020 [44]
2019 [51]
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Chemistry [5]
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共729条,第1-10条
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内容类型:期刊论文
专题:上海药物研究所
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A validated LC-MS/MS method for the quantitation of daratumumab in rat serum using rapid tryptic digestion without IgG purification and reduction
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 243, 页码: 8
作者:
Li, Weiqiang
;
Huang, Wensi
;
Yu, Xiong
;
Chen, Chong
;
Yuan, Yali
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Daratumumab
LC-MS/MS
Surrogate peptide
Pharmacokinetics
Mechanochemical aerobic oxidative Heck coupling by polymer-assisted grinding: cyclodextrin additive facilitating regioselectivity control
期刊论文
OAI收割
GREEN CHEMISTRY, 2024, 页码: 10
作者:
Xiang, Keyu
;
Shou, Haowen
;
Hu, Chenhui
;
Su, Weike
;
Yu, Jingbo
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 20
作者:
Niu, Pengpeng
;
Tao, Yanxin
;
Lin, Guohao
;
Xu, Huiqi
;
Meng, Qingyuan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 14
作者:
Liu, Zhihao
;
Lin, Min
;
Liu, Chenyu
;
Chen, Xin
;
Chen, Qian
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
A novel donor-acceptor fluorescent probe for the fluorogenic/ chromogenic detection and bioimaging of nitric oxide
期刊论文
OAI收割
ANALYTICA CHIMICA ACTA, 2024, 卷号: 1296, 页码: 12
作者:
Hu, Jingxin
;
Wang, Ruiya
;
Liao, Wantao
;
Hu, Jinhui
;
Li, Lanqing
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Fluorescent probe
Donor-acceptor type
Nitric oxide
Colorimetric detection
Bioimaging
Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4855-4869
作者:
Gu, Chenming
;
Liu, Jiayuan
;
Qian, Fei
;
Yu, Wenchao
;
Huang, Doudou
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Siteselective and Enantiocomplementary C(sp
3
)-H Oxyfunctionalization for Synthesis of α-Hydroxy Acids
期刊论文
OAI收割
ACS CATALYSIS, 2024, 卷号: 14, 期号: 7, 页码: 4463-4470
作者:
Lian, Xin
;
Mao, Yingle
;
Fu, Zunyun
;
Zhang, Weijie
;
Chen, Jiayan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
biocatalysis
C(sp(3))-H functionalization
dioxygenases
asymmetric synthesis
alpha-hydroxyacids
Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 19
作者:
Chen, Yuting
;
Wang, Zekun
;
Zhang, Junjie
;
Shi, Qiongyu
;
Yang, Hong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
PRMT5
Nucleoside derivatives
Methyltransferases
Structure -activity relationship
A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 11
作者:
Huang, Wen-si
;
Li, Wei-qiang
;
Yu, Xiong
;
Xue, Ming-zhen
;
Yuan, Ya-li
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/04/09
Anti -gastric cancer monoclonal antibody
Ramucirumab
LC -MS/MS
Method validation
Surrogate peptide
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/25