中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [69]
采集方式
OAI收割 [69]
内容类型
期刊论文 [68]
会议论文 [1]
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2024 [4]
2023 [6]
2022 [11]
2021 [2]
2020 [4]
2019 [4]
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Pharmacolo... [2]
Cell Biolo... [1]
Chemistry [1]
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浏览/检索结果:
共69条,第1-10条
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专题:上海药物研究所
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In vitro inhibition of six active sesquiterpenoids in zedoary turmeric oil on human liver cytochrome P450 enzymes
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 322, 页码: 10
作者:
Liu, Suyan
;
Zhao, Yong
;
Tang, Xuan
;
Yang, Junling
;
Pan, Chen
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
Sesquiterpenoids
Inhibition
CYP450s
Drug-drug interactions
Mechanism
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG
期刊论文
OAI收割
BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14
作者:
Liu, Zhipei
;
Wang, Feng
;
Yuan, Hui
;
Tian, Fuyun
;
Yang, Chuanyan
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/13
hERG
K525N
Gating Polarity
Voltage-Sensing Domain
LQT2
Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11
作者:
Wang, Weiqiang
;
Chen, Chong
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/01/16
LN005
Metabolism
Peptide -drug conjugates
UHPLC-HRMS
Doxorubicin
Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS
期刊论文
OAI收割
XENOBIOTICA, 2024, 页码: 9
作者:
Yuan, Yali
;
Wang, Weiqiang
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/19
peptide-drug conjugate
PDC
LN005
metabolite identification
liver S9s
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10
作者:
Zhang, Yumin
;
Sun, Yuan
;
Xie, Yuanchao
;
Shang, Weijuan
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Building Block Extractor: An MS/MS Data Mining Tool for Targeted Discovery of Natural Products with Specified Features
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2023, 页码: 8
作者:
Zhu, Dafu
;
Yuan, Jie
;
Yue, Quanqi
;
Zhao, Yinggong
;
Yu, Shan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
Small molecule drugs promote repopulation of transplanted hepatocytes by stimulating cell dedifferentiation
期刊论文
OAI收割
JHEP REPORTS, 2023, 卷号: 5, 期号: 4, 页码: 11
作者:
Jiang, Mengmeng
;
Guo, Ren
;
Ai, Yan
;
Wang, Gang
;
Tang, Peilan
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/10/17
Hepatocyte transplantation
Hepatocyte expansion
Dedifferentiation
Hepatocyte progenitor cells
Small molecule compounds
A RIPK3-independent role of MLKL in suppressing parthanatos promotes immune evasion in hepatocellular carcinoma
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15
作者:
Jiang, Xifei
;
Deng, Wenjia
;
Tao, Siyao
;
Tang, Zheng
;
Chen, Yuehong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/04/10
Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 21
作者:
Gao, Dingding
;
Tang, Shuai
;
Cen, Yixin
;
Yuan, Liang
;
Lan, Xiaojing
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10