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浏览/检索结果: 共356条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Lindenane sesquiterpenoid dimers from Chloranthus japonicus improve LDL uptake by regulating PCSK9 and LDLR 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 142, 页码: 13 作者:  Guo, Pengju;  Chen, Tong;  Hu, Xianggang;  Duan, Yelin;  Zheng, Liu   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/01/16 Chloranthus japonicas  Lindenane sesquiterpenoid dimers  PCSK9  LDLR   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L 期刊论文  OAI收割 CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28 作者:  Li, Xin;  Wu, Xiaowei;  Nie, Shenyou;  Zhao, Jidong;  Yao, Yuan   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/19 MLL-rearranged leukemia  super elongation complexes  small-molecule inhibitor  protein-protein interaction  cancer therapeutics   Discovery of novel cGAS inhibitors based on natural flavonoids 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 14 作者:  Li, Jiameng;  Xiong, Muya;  Liu, Jiayuan;  Zhang, Fengping;  Li, Minjun   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/08 Cyclic GMP-AMP synthase  Inhibitor  Flavonoids  Crystal structure  Virtual screening   Chemical Inhibitors Targeting the Oncogenic m6A Modifying Proteins 期刊论文  OAI收割 ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022 作者:  Huang, Yue;  Xia, Wenyang;  Dong, Ze;  Yang, Cai-Guang   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/11 Design, synthesis, and biological evaluation of novel spirocyclic compounds as potential anti-glioblastoma agents 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 22 作者:  Zhu, Heping;  Song, Xiaomin;  Pan, Yihui;  Li, Ming;  Chen, Liang   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Glioblastoma  Spirocyclic compounds  Drug design  Antiproliferation   Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 14, 期号: 8, 页码: 1073-1078 作者:  Seydimemet, Mengnisa;  Yang, Yixuan;  Lv, Yuhan;  Liu, Jiaxiang;  Yan, Ziqin   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 DNA-encoded library technology  Pyrimidine-focusedDNA-encodedlibrary  BRD4  Affinity screening  Inhibitor   Discovery of Novel SIRT1/2 Inhibitors with Effective Cytotoxicity against Human Leukemia Cells 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 页码: 11 作者:  Cai, Haiyan;  Wang, Yingying;  Zhang, Jing;  Wei, Zhenquan;  Yan, Teng   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/10/17 Sequence-based drug design as a concept in computational drug design 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21 作者:  Chen, Lifan;  Fan, Zisheng;  Chang, Jie;  Yang, Ruirui;  Hou, Hui   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/10/17 A comprehensive analysis of the Bencao (herbal) small RNA Atlas reveals novel RNA therapeutics for treating human diseases 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 19 作者:  Cao, Yinghao;  Lin, Yexuan;  Sun, Na;  Du, Xinyi;  Dong, Yixin   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 small RNA  herbal decoction  cross-kingdom regulation  traditional Chinese medicine  RNA oligonucleotide drug  RNA therapeutics  Bencao small RNA Atlas