机构

• 上海药物研究所 [43]

采集方式

• OAI收割 [43]

内容类型

• 期刊论文 [43]

发表日期

• 2023 [43]

学科主题

筛选

浏览/检索结果: 共43条，第1-10条 帮助 限定条件 发表日期：2023    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Autoimmune diseases: targets, biology, and drug discovery 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12 作者:  Li, Shu-jie;  Wu, Yan-li;  Chen, Juan-hua;  Shen, Shi-yi;  Duan, Jia   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/26 autoimmune disease  autoantigen  immunotherapy  type 1 diabetes  insulin  drug discovery   Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/19 Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells 期刊论文  OAI收割 MOLECULAR PLANT, 2023, 卷号: 16, 期号: 12, 页码: 1990-2003 作者:  Lin, Jia-Ling;  Chen, Longxian;  Wu, Wen-Kai;  Guo, Xiao-Xiang;  Yu, Cheng-Hui   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/01/26 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids 期刊论文  OAI收割 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2023, 卷号: 185, 页码: 13-25 作者:  Zhao, Chengcheng;  Jiang, Xiangrui;  Peng, Liyuan;  Zhang, Yan;  Li, Huihui   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/01/16 Heart failure  Hypertrophy  Epoxyeicosatrienoic acids  Soluble epoxide hydrolase   Indole-3-Propionic Acid, a Gut Microbiota Metabolite, Protects Against the Development of Postoperative Delirium 期刊论文  OAI收割 ANNALS OF SURGERY, 2023, 卷号: 278, 期号: 6, 页码: E1164-E1174 作者:  Zhou, Xue;  Wu, Xinbo;  Wu, Yan;  Yang, Liuyue;  Shi, Eleanor   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/04/09 gut microbiota  indole-3-propionic acid  anesthesia  surgery  postoperative delirium   Sterically demanding Csp2(ortho-substitution)-Csp3(tertiary) bond formation via carboxylate-directed Mizoroki-Heck reaction under extra-ligand-free conditions 期刊论文  OAI收割 ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 页码: 5 作者:  Zeng, Wei;  Chen, Ai-Wen;  Yan, Ming-Jie;  Wang, Jie   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/01/16 Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：59/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   Deubiquitylating Enzymes in Cancer and Immunity 期刊论文  OAI收割 ADVANCED SCIENCE, 2023, 页码: 37 作者:  Ren, Jiang;  Yu, Peng;  Liu, Sijia;  Li, Ran;  Niu, Xin   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 cancer  deubiquitylating enzymes (DUBs)  immunity  therapeutic approach