中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [109]
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OAI收割 [109]
内容类型
期刊论文 [107]
会议论文 [2]
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2024 [4]
2023 [12]
2022 [12]
2021 [6]
2020 [7]
2019 [10]
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Chemistry [3]
Pharmacolo... [3]
Biochemist... [1]
Oncology [1]
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浏览/检索结果:
共109条,第1-10条
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专题:上海药物研究所
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Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
期刊论文
OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:
Bian, Yi-cong
;
Meng, Jian
;
Hu, Tao
;
Ma, Sheng
;
Huang, Chen-rong
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
HSK7653
long-acting dipeptidyl peptidase-4 inhibitor
mass balance
metabolism
pharmacokinetics
radiolabelled
Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in B-arrestin 1/2 signaling
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2024, 卷号: 968, 页码: 17
作者:
Lei, Saifei
;
Meng, Qian
;
Liu, Yanyun
;
Liu, Qiaofeng
;
Dai, Antao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/22
GLP-1R
B-arrestin 1/2
Biased agonism
Bioluminescence resonance energy transfer
Proteomics profiling
Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner
期刊论文
OAI收割
METABOLISM-CLINICAL AND EXPERIMENTAL, 2024, 卷号: 152, 页码: 12
作者:
Meng, Meiyao
;
Cao, Yuxiang
;
Qiu, Jin
;
Shan, Guangyu
;
Wang, Yingwen
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/25
Triglyceride metabolism
ZNF638
Adipose tissue
Angptl8
Lipoprotein lipase
Quantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting the PDGFRβ/PI3K/AKT pathway
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Meng, Qian
;
Zhu, Hongwen
;
Li, Yuanyuan
;
Peng, Xiaotian
;
Wang, Tianming
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Yinchenzhufu decoction
proteomics
cholestasis
liver fibrosis
PDGFR beta/PI3K/AKT
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14
作者:
Xu, Zhuo
;
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Zhu, Mengying
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Otilonium Bromide
Deubiquitinase
USP28
Selective inhibitor
Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Wen, Xin
;
Zhang, Minmin
;
Duan, Zhiqiang
;
Suo, Yanrui
;
Lu, Weiwei
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/10/17
Preparation and characterization of nanobodies targeting SARS-CoV-2 papain-like protease
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106267
作者:
Qiao, Huarui
;
Li, Lingyun
;
Wang, Lu
;
Yu, Haijun
;
Hu, Fangzheng
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
SARS-CoV-2
Papain like protease (PLpro)
Nanobody
PLpro inhibitor
A procedure for producing an anti-AXL nanobody in E. coli
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106268
作者:
Lan, Zhongyun
;
Li, Lingyun
;
Sun, Yili
;
Meng, Xiangjing
;
Shi, Zhenzhong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/27
AXL
Nanobody
Expression
Purification
Proteomics of adjacent-to-tumor samples uncovers clinically relevant biological events in hepatocellular carcinoma
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 8, 页码: 17
作者:
Zhu, Hongwen
;
Lin, Youpei
;
Lu, Dayun
;
Wang, Shisheng
;
Liu, Yuejia
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
proteomics
hepatocellular carcinoma
normal tissue adjacent to tumor
heterogeneity