中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [115]
采集方式
OAI收割 [115]
内容类型
期刊论文 [113]
会议论文 [2]
发表日期
2024 [3]
2023 [11]
2022 [14]
2021 [8]
2020 [12]
2019 [7]
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Biochemist... [1]
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浏览/检索结果:
共115条,第1-10条
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专题:上海药物研究所
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PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 12
作者:
Zhang, Shunan
;
Lai, Yi
;
Pan, Jiaxing
;
Saeed, Madiha
;
Li, Shiqin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/04/09
active tumor targeting
nanosensitizer
PROTAC prodrug
radiation therapy
tumor microenvironment
Palladium-Catalyzed Deuteration of Arylketone Oxime Ethers
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 页码: 7
作者:
Wang, Zhen-Yu
;
Zhang, Xu
;
Chen, Wen-Qing
;
Sun, Guo-Dong
;
Wang, Xing
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/13
C-C Bond Cleavage
Deacylation
Regioselective Deuteration
Difunctionalization
Palladium Catalysis
Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Liu, Min -Min
;
Yang, Yu-Ting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Imidazo[124] triazole derivatives
Fluorescence property
SHP1
Bioactivity
Cellular imaging
Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study
期刊论文
OAI收割
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12
作者:
Zhao, Tian-Tian
;
Hu, Hao-Jie
;
Gao, Li-Xin
;
Zhou, Yu-Bo
;
Zhu, Yun-Long
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Protein tyrosine phosphatases inhibitors
PTP1B inhibitors
Mechanism study
Molecular dynamics
Addition of a-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 16
作者:
Yang, Ze-xian
;
Zhang, Yu
;
Wang, Qing
;
Zhang, Lei
;
Liu, Yi-fei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Parkinson's disease
gut-brain axis
a-Synuclein
inflammation
microbiota
intestinal mouse coloclysis model
Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Wen, Xin
;
Zhang, Minmin
;
Duan, Zhiqiang
;
Suo, Yanrui
;
Lu, Weiwei
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/10/17
Photophysical Exploration of Alectinib and Rilpivirine: Insights from Theory and Experiment
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 16, 页码: 16
作者:
Zhang, Chun
;
Yang, Yuting
;
Gan, Suya
;
Ren, Aimin
;
Zhou, Yu-Bo
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
fluorescence imaging
Alectinib
Rilpivirine
quantum chemistry
Design, Synthesis and Evaluation of Fluorescent Properties of Benzothiazole Derivatives
期刊论文
OAI收割
CHEMPHYSCHEM, 2023, 页码: 13
作者:
Sun, Yi-Tao
;
Zhang, Chun
;
Gao, Li-Xin
;
Liu, Min-Min
;
Yang, Yuting
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
Construction of Indole-Fused Seven- and Eight-Membered Azaheterocycles via a Tandem Pd/NBE-Catalyzed Decarbonylation and Dual C-H Activation Sequence
期刊论文
OAI收割
ORGANIC LETTERS, 2023, 卷号: 25, 期号: 29, 页码: 5406-5410
作者:
Liu, Yu-Wen
;
Wang, Meng-Meng
;
Zhang, Yun-Qian
;
Xu, Hui
;
Dai, Hui-Xiong
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 23
作者:
Wang, Xin
;
Lin, Di-Hang
;
Yan, Yue
;
Wang, An-Hui
;
Liao, Jiaoyang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
PIWI
piRNAs
PIWI-Ins
translational activation
spermatid development
male fertility