中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [326]
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浏览/检索结果: 共326条,第1-10条 帮助

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Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with Gs proteins 期刊论文  OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13
作者:  
Cong, Zhaotong;  Zhao, Fenghui;  Li, Yang;  Luo, Gan;  Mai, Yiting
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An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG 期刊论文  OAI收割
BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14
作者:  
Liu, Zhipei;  Wang, Feng;  Yuan, Hui;  Tian, Fuyun;  Yang, Chuanyan
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Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10
作者:  
Chen, Guofeng;  Xie, Hang;  Liu, Jiayuan;  Shao, Qiang;  Li, Minjun
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The new direction of drug development: Degradation of undruggable targets through targeting chimera technology 期刊论文  OAI收割
MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54
作者:  
Liang, Xuewu;  Ren, Hairu;  Han, Fengyang;  Liang, Renwen;  Zhao, Jiayan
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An inulin-type fructan isolated from Serratula chinensis alleviated the dextran sulfate sodium-induced colitis in mice through regulation of intestinal barrier and gut microbiota 期刊论文  OAI收割
CARBOHYDRATE POLYMERS, 2023, 卷号: 320, 页码: 12
作者:  
Li, Zhenwei;  Wen, Qiuyi;  Pi, Jiaju;  Zhang, Daidi;  Nie, Jinchun
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Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 22, 页码: 15269-15287
作者:  
Hu, Linghao;  Li, Huiyun;  Qin, Junlin;  Yang, Dan;  Liu, Jieming
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Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:  
Li, Cuixia;  Wu, Yiran;  Wang, Wenli;  Xu, Lu;  Zhou, Yan
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Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes 期刊论文  OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9
作者:  
Sun, Zengchao;  Wang, Lu;  Li, Lingyun;  Sun, Yili;  Zhang, Daizhou
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Structural insights into the interaction of three Y- shaped ligands with PI3Kα 期刊论文  OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 34, 页码: 9
作者:  
Zhou, Qingtong;  Liu, Xiao;  Neri, Dario;  Li, Wenxin;  Favalli, Nicholas
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Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:  
Rao, Danni;  Yang, Tao;  Feng, Huixu;  An, Qi;  Zhang, Shaofeng
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