机构

• 上海药物研究所 [7]
• 上海生物化学与细胞生... [2]

采集方式

• OAI收割 [9]

内容类型

• 期刊论文 [9]

发表日期

• 2021 [1]
• 2018 [1]
• 2017 [1]
• 2012 [2]
• 2009 [4]

学科主题

• Neuroscien... [1]
• Research &... [1]

筛选

浏览/检索结果: 共9条，第1-9条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Zhang, Yong-Mei;  Ye, Lu-Yu;  Li, Tian-Yu;  Guo, Fan;  Guo, Fei   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/01/04 YL-0919  medial prefrontal cortex  GABAergic neurons  5-HT1A receptor  GAD67-GFP transgenic mice  disinhibition  fluoxetine  electrophysiological recording   Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3117-3125 作者:  Liu, Wenwen;  Wang, Huan;  Li, Xiaokang;  Xu, Yixiang;  Zhang, Jian   |  收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 Depression  Cognitive impairment  Multitarget-directed ligand  5-HT1A agonist  5-HT reuptake inhibition  ChE inhibition   Novel Vilazodone Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 2708-2721 作者:  Li, Xiaokang;  Wang, Huan;  Xu, Yixiang;  Liu, Wenwen;  Gong, Qi   |  收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 Alzheimer's disease  depression  multitarget-directed ligand  ChE inhibition  5-HT1A agonist  5-HT reuptake inhibition   Synthesis and antidepressant activity of arylalkanol-piperidine derivatives as triple reuptake inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 123-136 作者:  Zheng, Yong-Yong;  Guo, Lin;  Zhen, Xue-Chu;  Li, Jian-Qi   |  收藏  |  浏览/下载：9/0  |  提交时间：2019/01/08 Arylalkanol-piperidine derivatives  Triple reuptake inhibitor  Antidepressant   Design,synthesis and bioactivity of aryl piperazine benzo[b]oxazine derivatives 期刊论文  OAI收割 Acta Pharmaceutica Sinica, 2012, 卷号: 47, 期号: 6, 页码: 755-763 作者:  Zheng Yongyong;  Xie Peng;  Zhang Jin;  Li Jianqi;  Guo Lin   |  收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 5-HT_(1A)  aryl piperazine benzo [b] oxazine derivatives  pharmacophore model  5-HT reuptake  5-HT_(1A)   A novel compound N-1, N-5-(Z)-N-10-(E)-tri-p-coumaroylspermidine isolated from Carthamus tinctorius L. and acting by serotonin transporter inhibition 期刊论文  OAI收割 EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2009, 卷号: 19, 期号: 10, 页码: 749-758 作者:  Zhao, Gang;  Gai, Yue;  Chu, Wen-Jing;  Qin, Guo-Wei;  Guo, Li-He   |  收藏  |  浏览/下载：9/0  |  提交时间：2019/01/08 Safflower  N-1,N-5-(Z)-N-10-(E)-tri-p-coumaroylspermidine  Serotonin transporter  Reuptake  Inhibitor   Caulis Sinomenii Extracts Activate DA/NE Transporter and Inhibit 5HT Transporter 期刊论文  OAI收割 EXPERIMENTAL BIOLOGY AND MEDICINE, 2009, 卷号: 234, 期号: 8, 页码: 976-985 作者:  Zhao, Gang;  Bi, Cheng;  Qin, Guo-Wei;  Guo, Li-He   |  收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Caulis Sinomenii  dopamine  norepinephrine  serotonin  reuptake modulator  transporter   A novel compound N-1, N-5-(Z)-N-10-(E)-tri-p-coumaroylspermidine isolated from Carthamus tinctorius L. and acting by serotonin transporter inhibition 期刊论文  OAI收割 EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2009, 卷号: 19, 期号: 10, 页码: 749-758 作者:  Zhao, G;  Gai, Y;  Chu, WJ;  Qin, GW;  Guo, LH 收藏  |  浏览/下载：13/0  |  提交时间：2015/07/22 Safflower  N-1  Serotonin transporter  Reuptake  Inhibitor  N-5-(Z)-N-10-(E)-tri-p-coumaroylspermidine   Caulis Sinomenii Extracts Activate DA/NE Transporter and Inhibit 5HT Transporter 期刊论文  OAI收割 EXPERIMENTAL BIOLOGY AND MEDICINE, 2009, 卷号: 234, 期号: 8, 页码: 976-985 作者:  Zhao, G;  Bi, C;  Qin, GW;  Guo, LH 收藏  |  浏览/下载：25/0  |  提交时间：2015/07/22 Caulis Sinomenii  dopamine  norepinephrine  serotonin  reuptake modulator  transporter